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Allosteric networks in thrombin distinguish procoagulant vs. anticoagulant activities
Author / Creator:Gasper, Paul M. ; Fuglestad, Brian ; Komives, Elizabeth A. ; Markwick, Phineus R. L. ; McCammon, J. Andrew
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2012-12, Vol.109 (52), p.21216-21222
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Recombinant human soluble thrombomodulin is associated with attenuation of sepsis-induced renal impairment by inhibition of extracellular histone release
Author / Creator:Akatsuka, Masayuki ; Masuda, Yoshiki ; Tatsumi, Hiroomi ; Yamakage, Michiaki
Publisher:United States: Public Library of Science
Journal title:PloS one, 2020-01, Vol.15 (1), p.e0228093-e0228093
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The fifth epidermal growth factor-like region of thrombomodulin exerts cytoprotective function and prevents SOS in a murine model
Author / Creator:Ikezoe, T ; Yang, J ; Nishioka, C ; Pan, B ; Xu, K ; Furihata, M ; Nakamura, K ; Yurimoto, H ; Sakai, Y ; Honda, G ; Yokoyama, A
Publisher:London: Nature Publishing Group UK
Journal title:Bone marrow transplantation (Basingstoke), 2017-01, Vol.52 (1), p.73-79
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Pathogenesis of disseminated intravascular coagulation in patients with acute promyelocytic leukemia, and its treatment using recombinant human soluble thrombomodulin
Author / Creator:Ikezoe, Takayuki
Publisher:Tokyo: Springer Japan
Journal title:International journal of hematology, 2014-07, Vol.100 (1), p.27-37
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Vascular immunotargeting to endothelial determinant ICAM-1 enables optimal partnering of recombinant scFv-thrombomodulin fusion with endogenous cofactor
Author / Creator:Greineder, Colin F ; Chacko, Ann-Marie ; Zaytsev, Sergei ; Zern, Blaine J ; Carnemolla, Ronald ; Hood, Elizabeth D ; Han, Jingyan ; Ding, Bi-Sen ; Esmon, Charles T ; Muzykantov, Vladimir R
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-11, Vol.8 (11), p.e80110
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Levels of protein C and soluble thrombomodulin in critically ill patients with acute kidney injury: a multicenter prospective observational study
Author / Creator:Bouchard, Josée ; Malhotra, Rakesh ; Shah, Shamik ; Kao, Yu-Ting ; Vaida, Florin ; Gupta, Akanksha ; Berg, David T ; Grinnell, Brian W ; Stofan, Brenda ; Tolwani, Ashita J ; Mehta, Ravindra L
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-03, Vol.10 (3), p.e0120770-e0120770
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Amino-Terminal Fusion of Epidermal Growth Factor 4,5,6 Domains of Human Thrombomodulin on Streptokinase Confers Anti-Reocclusion Characteristics along with Plasmin-Mediated Clot Specificity
Author / Creator:Maheshwari, Neeraj ; Kantipudi, Satish ; Maheshwari, Anand ; Arora, Kashika ; Vandana ; Kwatra, Neha ; Sahni, Girish
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-03, Vol.11 (3), p.e0150315-e0150315
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Rational Design of Protein C Activators
Author / Creator:Barranco-Medina, Sergio ; Murphy, Mary ; Pelc, Leslie ; Chen, Zhiwei ; Di Cera, Enrico ; Pozzi, Nicola
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-03, Vol.7 (1), p.44596-44596, Article 44596
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Dengue virus enhances thrombomodulin and ICAM-1 expression through the macrophage migration inhibitory factor induction of the MAPK and PI3K signaling pathways
Author / Creator:Yeh, Trai-Ming ; Liu, Shu-Hsiang ; Lin, Kao-Chang ; Kuo, Chieh ; Kuo, Shu-Yun ; Huang, Tzuu-Yuan ; Yen, Yong-Ren ; Wen, Rong-Kun ; Chen, Lien-Cheng ; Fu, Tsai-Feng
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-01, Vol.8 (1), p.e55018-e55018
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Recombinant Human Soluble Thrombomodulin Suppresses Monocyte Adhesion by Reducing Lipopolysaccharide-Induced Endothelial Cellular Stiffening
Author / Creator:Okamoto, Takayuki ; Kawamoto, Eiji ; Usuda, Haruki ; Tanaka, Tetsuya ; Nikai, Tetsuro ; Asanuma, Kunihiro ; Suzuki, Koji ; Shimaoka, Motomu ; Wada, Koichiro
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2020-07, Vol.9 (8), p.1811
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Structural basis for the anticoagulant activity of the thrombin–thrombomodulin complex
Author / Creator:Fuentes-Prior, Pablo ; Iwanaga, Yoriko ; Huber, Robert ; Pagila, Rene ; Rumennik, Galina ; Seto, Marian ; Morser, John ; Light, David R. ; Bode, Wolfram
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2000-03, Vol.404 (6777), p.518-525
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Activation of Protein C by the Thrombin-Thrombomodulin Complex: Cooperative Roles of Arg-35 of Thrombin and Arg-67 of Protein C
Author / Creator:Yang, Likui ; Manithody, Chandrashekhara ; Rezaie, Alireza R.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2006-01, Vol.103 (4), p.879-884
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Molecular mechanisms of thrombin function
Author / Creator:Di Cera, E ; Dang, Q D ; Ayala, Y M
Publisher:Switzerland: Springer Nature B.V
Journal title:Cellular and molecular life sciences : CMLS, 1997-09, Vol.53 (9), p.701-730
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Thrombin-Activatable Fibrinolysis Inhibitor
Author / Creator:Marx, Pauline F
Publisher:United Arab Emirates: Bentham Science Publishers Ltd
Journal title:Current medicinal chemistry, 2004-09, Vol.11 (17), p.2335-2348
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The effect of cigarette smoke extract on thrombomodulin- thrombin binding： an atomic force microscopy study
Author / Creator:Wei, YuJie ; Zhang, XueJie ; Xu, Li ; Yi, ShaoQiong ; Li, Yi ; Fang, XiaoHong ; Liu, HuiLiang
Publisher:Beijing: Science China Press
Journal title:Science China. Life sciences, 2012-10, Vol.55 (10), p.891-897
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Production of large quantities of isotopically labeled protein in Pichia pastoris by fermentation
Author / Creator:Wood, M.J ; Komives, E.A
Publisher:Netherlands: Springer Nature B.V
Journal title:Journal of biomolecular NMR, 1999-02, Vol.13 (2), p.149-159
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Solution structure of the smallest cofactor-active fragment of thrombomodulin
Author / Creator:Wood, Matthew J. ; Sampoli Benitez, Benedetta A. ; Komives, Elizabeth A.
Publisher:New York: Nature Publishing Group US
Journal title:Nature Structural Biology, 2000-03, Vol.7 (3), p.200-204
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The plot thickens: How thrombin modulates blood clotting
Author / Creator:Overduin, Michael ; de Beer, Tonny
Publisher:New York: Nature Publishing Group US
Journal title:Nature Structural Biology, 2000-04, Vol.7 (4), p.267-269
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The Fifth Epidermal Growth Factor-Like Domain of Thrombomodulin does not have an Epidermal Growth Factor-Like Disulfide Bonding Pattern
Author / Creator:White, Christopher E. ; Hunter, Michael J. ; Meininger, David P. ; Garrod, Siv ; Komives, Elizabeth A.
Publisher:United States: National Academy of Sciences of the United States of America
Journal title:Proceedings of the National Academy of Sciences - PNAS, 1996-09, Vol.93 (19), p.10177-10182
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Thrombomodulin Ala455Val Dimorphism Is Not Associated with Pre-Eclampsia in Australian and New Zealand Women
Author / Creator:Borg, Anthony J. ; Higgins, John R. ; Brennecke, Shaun P. ; Moses, Eric K.
Publisher:Basel, Switzerland: Karger
Journal title:Gynecologic and obstetric investigation, 2002-01, Vol.54 (1), p.43-45
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Showing 1 to 20 of 20 results

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Allosteric networks in thrombin distinguish procoagulant vs. anticoagulant activities

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Recombinant human soluble thrombomodulin is associated with attenuation of sepsis-induced renal impairment by inhibition of extracellular histone release

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The fifth epidermal growth factor-like region of thrombomodulin exerts cytoprotective function and prevents SOS in a murine model

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Pathogenesis of disseminated intravascular coagulation in patients with acute promyelocytic leukemia, and its treatment using recombinant human soluble thrombomodulin

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Vascular immunotargeting to endothelial determinant ICAM-1 enables optimal partnering of recombinant scFv-thrombomodulin fusion with endogenous cofactor

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Levels of protein C and soluble thrombomodulin in critically ill patients with acute kidney injury: a multicenter prospective observational study

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Amino-Terminal Fusion of Epidermal Growth Factor 4,5,6 Domains of Human Thrombomodulin on Streptokinase Confers Anti-Reocclusion Characteristics along with Plasmin-Mediated Clot Specificity

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Rational Design of Protein C Activators

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Dengue virus enhances thrombomodulin and ICAM-1 expression through the macrophage migration inhibitory factor induction of the MAPK and PI3K signaling pathways

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Recombinant Human Soluble Thrombomodulin Suppresses Monocyte Adhesion by Reducing Lipopolysaccharide-Induced Endothelial Cellular Stiffening

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Structural basis for the anticoagulant activity of the thrombin–thrombomodulin complex

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Activation of Protein C by the Thrombin-Thrombomodulin Complex: Cooperative Roles of Arg-35 of Thrombin and Arg-67 of Protein C

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Molecular mechanisms of thrombin function

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Thrombin-Activatable Fibrinolysis Inhibitor

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The effect of cigarette smoke extract on thrombomodulin- thrombin binding： an atomic force microscopy study

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Production of large quantities of isotopically labeled protein in Pichia pastoris by fermentation

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Solution structure of the smallest cofactor-active fragment of thrombomodulin

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The plot thickens: How thrombin modulates blood clotting

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The Fifth Epidermal Growth Factor-Like Domain of Thrombomodulin does not have an Epidermal Growth Factor-Like Disulfide Bonding Pattern

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Thrombomodulin Ala455Val Dimorphism Is Not Associated with Pre-Eclampsia in Australian and New Zealand Women

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