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ArticlesPeer ReviewedFull Text
Apparent latent structure within the UK Biobank sample has implications for epidemiological analysis
Author / Creator:Haworth, Simon ; Mitchell, Ruth ; Corbin, Laura ; Wade, Kaitlin H. ; Dudding, Tom ; Budu-Aggrey, Ashley ; Carslake, David ; Hemani, Gibran ; Paternoster, Lavinia ; Smith, George Davey ; Davies, Neil ; Lawson, Daniel J. ; J. Timpson, Nicholas
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-01, Vol.10 (1), p.333-9, Article 333
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Therapeutic potential of IL6R blockade for the treatment of sepsis and sepsis-related death: A Mendelian randomisation study
Author / Creator:Hamilton, Fergus W. ; Thomas, Matt ; Arnold, David ; Palmer, Tom ; Moran, Ed ; Mentzer, Alexander J. ; Maskell, Nick ; Baillie, Kenneth ; Summers, Charlotte ; Hingorani, Aroon ; MacGowan, Alasdair ; Khandaker, Golam M. ; Mitchell, Ruth ; Davey Smith, George ; Ghazal, Peter ; Timpson, Nicholas J.
Publisher:United States: Public Library of Science
Journal title:PLoS medicine, 2023-01, Vol.20 (1), p.e1004174
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ArticlesPeer ReviewedFull Text
Obesity and Multiple Sclerosis: A Mendelian Randomization Study
Author / Creator:Mokry, Lauren E. ; Ross, Stephanie ; Timpson, Nicholas J. ; Sawcer, Stephen ; Davey Smith, George ; Richards, J. Brent
Publisher:United States: Public Library of Science
Journal title:PLoS medicine, 2016-06, Vol.13 (6), p.e1002053-e1002053
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ArticlesPeer ReviewedFull Text
Genetic architecture: the shape of the genetic contribution to human traits and disease
Author / Creator:Timpson, Nicholas J. ; Greenwood, Celia M. T. ; Soranzo, Nicole ; Lawson, Daniel J. ; Richards, J. Brent
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Genetics, 2018-02, Vol.19 (2), p.110-124
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ArticlesPeer ReviewedFull Text
Using published data in Mendelian randomization: a blueprint for efficient identification of causal risk factors
Author / Creator:Burgess, Stephen ; Scott, Robert A. ; Timpson, Nicholas J. ; Smith, George Davey ; Thompson, Simon G.
Publisher:Dordrecht: Springer
Journal title:European journal of epidemiology, 2015-07, Vol.30 (7), p.543-552
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ArticlesPeer ReviewedFull Text
Mental health before and during the COVID-19 pandemic in two longitudinal UK population cohorts
Author / Creator:Kwong, Alex S. F. ; Pearson, Rebecca M. ; Adams, Mark J. ; Northstone, Kate ; Tilling, Kate ; Smith, Daniel ; Fawns-Ritchie, Chloe ; Bould, Helen ; Warne, Naomi ; Zammit, Stanley ; Gunnell, David J. ; Moran, Paul A. ; Micali, Nadia ; Reichenberg, Abraham ; Hickman, Matthew ; Rai, Dheeraj ; Haworth, Simon ; Campbell, Archie ; Altschul, Drew ; Flaig, Robin ; McIntosh, Andrew M. ; Lawlor, Deborah A. ; Porteous, David ; Timpson, Nicholas J.
Publisher:Cambridge, UK: Cambridge University Press
Journal title:British journal of psychiatry, 2021-06, Vol.218 (6), p.334-343
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The MR-Base platform supports systematic causal inference across the human phenome
Author / Creator:Hemani, Gibran ; Zheng, Jie ; Elsworth, Benjamin ; Wade, Kaitlin H ; Haberland, Valeriia ; Baird, Denis ; Laurin, Charles ; Burgess, Stephen ; Bowden, Jack ; Langdon, Ryan ; Tan, Vanessa Y ; Yarmolinsky, James ; Shihab, Hashem A ; Timpson, Nicholas J ; Evans, David M ; Relton, Caroline ; Martin, Richard M ; Davey Smith, George ; Gaunt, Tom R ; Haycock, Philip C
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2018-05, Vol.7
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ArticlesPeer ReviewedFull Text
Vitamin D levels and risk of type 1 diabetes: A Mendelian randomization study
Author / Creator:Manousaki, Despoina ; Harroud, Adil ; Mitchell, Ruth E. ; Ross, Stephanie ; Forgetta, Vince ; Timpson, Nicholas J. ; Smith, George Davey ; Polychronakos, Constantin ; Richards, J Brent
Publisher:United States: Public Library of Science
Journal title:PLoS medicine, 2021-02, Vol.18 (2), p.e1003536-e1003536
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ArticlesPeer ReviewedFull Text
Assessing Causality in the Association between Child Adiposity and Physical Activity Levels: A Mendelian Randomization Analysis
Author / Creator:Richmond, Rebecca C. ; Davey Smith, George ; Ness, Andy R. ; den Hoed, Marcel ; McMahon, George ; Timpson, Nicholas J.
Publisher:United States: Public Library of Science
Journal title:PLoS medicine, 2014-03, Vol.11 (3), p.e1001618-e1001618
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ArticlesPeer ReviewedFull Text
An observational and Mendelian randomisation study on iron status and sepsis
Author / Creator:Hamilton, Fergus ; Mitchell, Ruth ; Ahmed, Haroon ; Ghazal, Peter ; Timpson, Nicholas J.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2023-02, Vol.13 (1), p.2867-2867, Article 2867
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ArticlesPeer ReviewedFull Text
Identifying Critical Points of Trajectories of Depressive Symptoms from Childhood to Young Adulthood
Author / Creator:Kwong, Alex S. F. ; Manley, David ; Timpson, Nicholas J. ; Pearson, Rebecca M. ; Heron, Jon ; Sallis, Hannah ; Stergiakouli, Evie ; Davis, Oliver S. P. ; Leckie, George
Publisher:New York: Springer US
Journal title:Journal of youth and adolescence, 2019-04, Vol.48 (4), p.815-827
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ArticlesPeer ReviewedFull Text
Large-scale GWAS of food liking reveals genetic determinants and genetic correlations with distinct neurophysiological traits
Author / Creator:May-Wilson, Sebastian ; Matoba, Nana ; Wade, Kaitlin H. ; Hottenga, Jouke-Jan ; Concas, Maria Pina ; Mangino, Massimo ; Grzeszkowiak, Eryk J. ; Menni, Cristina ; Gasparini, Paolo ; Timpson, Nicholas J. ; Veldhuizen, Maria G. ; de Geus, Eco ; Wilson, James F. ; Pirastu, Nicola
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-05, Vol.13 (1), p.2743-2743, Article 2743
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ArticlesPeer ReviewedFull Text
A comparison of the genes and genesets identified by GWAS and EWAS of fifteen complex traits
Author / Creator:Battram, Thomas ; Gaunt, Tom R. ; Relton, Caroline L. ; Timpson, Nicholas J. ; Hemani, Gibran
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-12, Vol.13 (1), p.7816-7816, Article 7816
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ArticlesPeer ReviewedFull Text
Author Correction: An observational and Mendelian randomisation study on iron status and sepsis
Author / Creator:Hamilton, Fergus ; Mitchell, Ruth ; Ahmed, Haroon ; Ghazal, Peter ; Timpson, Nicholas J.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-03, Vol.14 (1), p.6033-1, Article 6033
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ArticlesPeer ReviewedFull Text
Influence of puberty timing on adiposity and cardiometabolic traits: A Mendelian randomisation study
Author / Creator:Bell, Joshua A. ; Carslake, David ; Wade, Kaitlin H. ; Richmond, Rebecca C. ; Langdon, Ryan J. ; Vincent, Emma E. ; Holmes, Michael V. ; Timpson, Nicholas J. ; Davey Smith, George
Publisher:United States: Public Library of Science
Journal title:PLoS medicine, 2018-08, Vol.15 (8), p.e1002641-e1002641
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ArticlesPeer ReviewedFull Text
Using multiple genetic variants as instrumental variables for modifiable risk factors
Author / Creator:Palmer, Tom M ; Lawlor, Debbie A ; Harbord, Roger M ; Sheehan, Nuala A ; Tobias, Jon H ; Timpson, Nicholas J ; Smith, George Davey ; Sterne, Jonathan AC
Publisher:London, England: SAGE Publications
Journal title:Statistical methods in medical research, 2012-06, Vol.21 (3), p.223-242
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ArticlesPeer ReviewedFull Text
The Effect of Elevated Body Mass Index on Ischemic Heart Disease Risk: Causal Estimates from a Mendelian Randomisation Approach
Author / Creator:Nordestgaard, Børge G. ; Palmer, Tom M. ; Benn, Marianne ; Zacho, Jeppe ; Tybjærg-Hansen, Anne ; Davey Smith, George ; Timpson, Nicholas J.
Publisher:United States: Public Library of Science
Journal title:PLoS medicine, 2012-05, Vol.9 (5), p.e1001212-e1001212
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ArticlesPeer ReviewedFull Text
A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci
Author / Creator:Hinds, David A ; McMahon, George ; Kiefer, Amy K ; Do, Chuong B ; Eriksson, Nicholas ; Evans, David M ; St Pourcain, Beate ; Ring, Susan M ; Mountain, Joanna L ; Francke, Uta ; Davey-Smith, George ; Timpson, Nicholas J ; Tung, Joyce Y
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2013-08, Vol.45 (8), p.907-911
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ArticlesPeer ReviewedFull Text
Extreme heat impacts on daily life and adaptive behaviours captured through lived experience
Author / Creator:Godwin, Joanne L ; Lo, Y T Eunice ; Maude, Ulrika ; Timpson, Nicholas J ; Northstone, Kate
Publisher:Bristol: IOP Publishing
Journal title:Environmental research letters, 2025-05, Vol.20 (5), p.54077
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ArticlesPeer ReviewedFull Text
HMOX1 genetic polymorphisms and outcomes in infectious disease: A systematic review
Author / Creator:Hamilton, Fergus W. ; Somers, Julia ; Mitchell, Ruth E. ; Ghazal, Peter ; Timpson, Nicholas J.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2022-05, Vol.17 (5), p.e0267399
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Showing 1 to 20 of 267 results

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Apparent latent structure within the UK Biobank sample has implications for epidemiological analysis

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Therapeutic potential of IL6R blockade for the treatment of sepsis and sepsis-related death: A Mendelian randomisation study

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Obesity and Multiple Sclerosis: A Mendelian Randomization Study

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Genetic architecture: the shape of the genetic contribution to human traits and disease

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Using published data in Mendelian randomization: a blueprint for efficient identification of causal risk factors

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Mental health before and during the COVID-19 pandemic in two longitudinal UK population cohorts

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The MR-Base platform supports systematic causal inference across the human phenome

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Vitamin D levels and risk of type 1 diabetes: A Mendelian randomization study

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Assessing Causality in the Association between Child Adiposity and Physical Activity Levels: A Mendelian Randomization Analysis

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An observational and Mendelian randomisation study on iron status and sepsis

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Identifying Critical Points of Trajectories of Depressive Symptoms from Childhood to Young Adulthood

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Large-scale GWAS of food liking reveals genetic determinants and genetic correlations with distinct neurophysiological traits

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A comparison of the genes and genesets identified by GWAS and EWAS of fifteen complex traits

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Author Correction: An observational and Mendelian randomisation study on iron status and sepsis

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Influence of puberty timing on adiposity and cardiometabolic traits: A Mendelian randomisation study

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Using multiple genetic variants as instrumental variables for modifiable risk factors

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The Effect of Elevated Body Mass Index on Ischemic Heart Disease Risk: Causal Estimates from a Mendelian Randomisation Approach

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A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci

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Extreme heat impacts on daily life and adaptive behaviours captured through lived experience

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HMOX1 genetic polymorphisms and outcomes in infectious disease: A systematic review

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