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ArticlesPeer ReviewedFull Text
Targeting EZH2 with tazemetostat
Author / Creator:Makita, Shinichi ; Tobinai, Kensei
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2018-05, Vol.19 (5), p.586-587
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Rituximab plus Lenalidomide in Advanced Untreated Follicular Lymphoma
Author / Creator:Morschhauser, Franck ; Fowler, Nathan H ; Feugier, Pierre ; Bouabdallah, Reda ; Tilly, Hervé ; Palomba, M. Lia ; Fruchart, Christophe ; Libby, Edward N ; Casasnovas, Rene-Olivier ; Flinn, Ian W ; Haioun, Corinne ; Maisonneuve, Hervé ; Ysebaert, Loic ; Bartlett, Nancy L ; Bouabdallah, Kamal ; Brice, Pauline ; Ribrag, Vincent ; Daguindau, Nicolas ; Le Gouill, Steven ; Pica, Gian M ; Martin Garcia-Sancho, Alejandro ; López-Guillermo, Armando ; Larouche, Jean-François ; Ando, Kiyoshi ; Gomes da Silva, Maria ; André, Marc ; Zachée, Pierre ; Sehn, Laurie H ; Tobinai, Kensei ; Cartron, Guillaume ; Liu, David ; Wang, Jianming ; Xerri, Luc ; Salles, Gilles A
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2018-09, Vol.379 (10), p.934-947
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Mogamulizumab versus vorinostat in previously treated cutaneous T-cell lymphoma (MAVORIC): an international, open-label, randomised, controlled phase 3 trial
Author / Creator:Kim, Youn H, Prof ; Bagot, Martine, Prof ; Pinter-Brown, Lauren, MD ; Rook, Alain H, MD ; Porcu, Pierluigi, MD ; Horwitz, Steven M, MD ; Whittaker, Sean, Prof ; Tokura, Yoshiki, MD ; Vermeer, Maarten, MD ; Zinzani, Pier Luigi, Prof ; Sokol, Lubomir, MD ; Morris, Stephen, MD ; Kim, Ellen J, Prof ; Ortiz-Romero, Pablo L, Prof ; Eradat, Herbert, MD ; Scarisbrick, Julia, MD ; Tsianakas, Athanasios, MD ; Elmets, Craig, MD ; Dalle, Stephane, Prof ; Fisher, David C, MD ; Halwani, Ahmad, MD ; Poligone, Brian, MD ; Greer, John, Prof ; Fierro, Maria Teresa, MD ; Khot, Amit, MD ; Moskowitz, Alison J, MD ; Musiek, Amy, MD ; Shustov, Andrei, MD ; Pro, Barbara, Prof ; Geskin, Larisa J, MD ; Dwyer, Karen, BA ; Moriya, Junji, MS ; Leoni, Mollie, MD ; Humphrey, Jeffrey S, MD ; Hudgens, Stacie, MA ; Grebennik, Dmitri O, MD ; Tobinai, Kensei, MD ; Duvic, Madeleine, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2018-09, Vol.19 (9), p.1192-1204
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ArticlesPeer ReviewedFull Text
Clinical development of anti‐CD19 chimeric antigen receptor T‐cell therapy for B‐cell non‐Hodgkin lymphoma
Author / Creator:Makita, Shinichi ; Yoshimura, Kiyoshi ; Tobinai, Kensei
Publisher:England: John Wiley and Sons Inc
Journal title:Cancer science, 2017-06, Vol.108 (6), p.1109-1118
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ArticlesPeer ReviewedFull Text
Brentuximab vedotin with chemotherapy for CD30-positive peripheral T-cell lymphoma (ECHELON-2): a global, double-blind, randomised, phase 3 trial
Author / Creator:Horwitz, Steven ; O'Connor, Owen A ; Advani, Ranjana ; Rossi, Giuseppe ; Kim, Won Seog ; Illés, Árpád ; Tobinai, Kensei ; Yeh, Su-Peng ; Shustov, Andrei ; Yuen, Sam ; Iyer, Swaminathan ; Hua, Zhaowei ; Little, Meredith ; Rao, Shangbang ; Woolery, Joseph ; Manley, Thomas ; Aboulafia, David ; Bartlett, Nancy ; Belada, David ; Yehuda, Dina Ben ; Benedetti, Fabio ; Bordessoule, Dominique ; Chang, Hung ; Cheong, June Weon ; Choi, Ilseung ; Colita, Andrei ; Congui, Angela Giovanna ; Dang, Nam ; Davison, Kelly ; de Guibert, Sophie ; Delwail, Vincent ; di Raimondo, Francesco ; Do, Young Rok ; Domingo, Eva ; Douvas, Michael ; Dreyling, Martin ; Fay, Keith ; Ferrero, Silvia Fernandez ; Flinn, Ian Winchester ; Forero-Torres, Andres ; Friedberg, Jonathan ; Fukuhara, Noriko ; Garcia-Marco, Jose ; Cruz, Jorge Gayoso ; Gurion, Ronit ; Christensen, Jacob Haaber ; Hajek, Roman ; Hatake, Kiyohiko ; Horowitz, Netanel ; Illes, Arpad ; Illidge, Tim ; Ishizawa, Kenichi ; Islas-Ohlmayer, Miguel ; Jacobsen, Eric ; Janakiram, Murali ; Jurczak, Wojciech ; Kaminski, Mark ; Kato, Koji ; Kim, Won Seog ; Iyer, Swaminathan ; Kuo, Ching-Yuan ; Lazaroiu, Mihaela Cornelia ; Lee, Jong-Seok ; Lennard, Anne ; LaRosee, Paul ; Levi, Itai ; Link, Brian ; Maisonneuve, Herve ; Maruyama, Dai ; Mayer, Jiri ; Mocikova, Heidi ; Morra, Enrica ; Morschhauser, Franck ; Munoz, Javier ; Nagai, Hirokazu ; Opat, Stephen ; Pettengell, Ruth ; Pezzutto, Antonio ; Pfreundschuh, Michael ; Pro, Barbara ; Reyes, Ruben ; Izquierdo, Antonia Rodriguez ; Rossi, Giuseppe ; Ruan, Jia ; Salles, Gilles ; Sarriera, Jose ; Shibayama, Hirohiko ; Shustov, Andrei ; Suh, Cheolwon ; Sureda, Anna ; Tanimoto, Mitsune ; Taniwaki, Masafumi ; Tilly, Herve ; Tsukamoto, Norifumi ; Wilhelm, Martin ; Yamamoto, Kazuhito ; Yeh, Su-Peng ; Yun, Hwan Jung ; Zain, Jasmine ; Zinzani, Pier Luigi
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2019-01, Vol.393 (10168), p.229-240
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ArticlesPeer ReviewedFull Text
Nationwide claims database analysis of treatment patterns, costs and survival of Japanese patients with diffuse large B-cell lymphoma
Author / Creator:Tsutsué, Saaya ; Tobinai, Kensei ; Yi, Jingbo ; Crawford, Bruce
Publisher:San Francisco: Public Library of Science
Journal title:PloS one, 2020-08, Vol.15 (8), p.e0237509-e0237509
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ArticlesPeer ReviewedFull Text
Oral histone deacetylase inhibitor tucidinostat (HBI‐8000) in patients with relapsed or refractory adult T‐cell leukemia/lymphoma: Phase IIb results
Author / Creator:Utsunomiya, Atae ; Izutsu, Koji ; Jo, Tatsuro ; Yoshida, Shinichiro ; Tsukasaki, Kunihiro ; Ando, Kiyoshi ; Choi, Ilseung ; Imaizumi, Yoshitaka ; Kato, Koji ; Kurosawa, Mitsutoshi ; Kusumoto, Shigeru ; Miyagi, Takashi ; Ohtsuka, Eiichi ; Sasaki, Osamu ; Shibayama, Hirohiko ; Shimoda, Kazuya ; Takamatsu, Yasushi ; Takano, Kuniko ; Yonekura, Kentaro ; Makita, Shinichi ; Taguchi, Jun ; Gillings, Mireille ; Onogi, Hiroshi ; Tobinai, Kensei
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2022-08, Vol.113 (8), p.2778-2787
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ArticlesPeer ReviewedFull Text
Phase I study of tirabrutinib (ONO‐4059/GS‐4059) in patients with relapsed or refractory B‐cell malignancies in Japan
Author / Creator:Munakata, Wataru ; Ando, Kiyoshi ; Hatake, Kiyohiko ; Fukuhara, Noriko ; Kinoshita, Tomohiro ; Fukuhara, Suguru ; Shirasugi, Yukari ; Yokoyama, Masahiro ; Ichikawa, Satoshi ; Ohmachi, Ken ; Gion, Naokazu ; Aoi, Arata ; Tobinai, Kensei
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2019-05, Vol.110 (5), p.1686-1694
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ArticlesPeer ReviewedFull Text
Mogamulizumab for relapsed adult T‐cell leukemia–lymphoma: Updated follow‐up analysis of phase I and II studies
Author / Creator:Ishida, Takashi ; Utsunomiya, Atae ; Jo, Tatsuro ; Yamamoto, Kazuhito ; Kato, Koji ; Yoshida, Shinichiro ; Takemoto, Shigeki ; Suzushima, Hitoshi ; Kobayashi, Yukio ; Imaizumi, Yoshitaka ; Yoshimura, Kenichi ; Kawamura, Kouichi ; Takahashi, Takeshi ; Tobinai, Kensei ; Ueda, Ryuzo
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2017-10, Vol.108 (10), p.2022-2029
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ArticlesPeer ReviewedFull Text
Phase 1 study of tazemetostat in Japanese patients with relapsed or refractory B‐cell lymphoma
Author / Creator:Munakata, Wataru ; Shirasugi, Yukari ; Tobinai, Kensei ; Onizuka, Makoto ; Makita, Shinichi ; Suzuki, Rikio ; Maruyama, Dai ; Kawai, Hidetsugu ; Izutsu, Koji ; Nakanishi, Tadashi ; Shiba, Sari ; Hojo, Seichiro ; Ando, Kiyoshi
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2021-03, Vol.112 (3), p.1123-1131
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ArticlesPeer ReviewedFull Text
Phase I study of OPB‐51602, an oral inhibitor of signal transducer and activator of transcription 3, in patients with relapsed/refractory hematological malignancies
Author / Creator:Ogura, Michinori ; Uchida, Toshiki ; Terui, Yasuhito ; Hayakawa, Fumihiko ; Kobayashi, Yukio ; Taniwaki, Masafumi ; Takamatsu, Yasushi ; Naoe, Tomoki ; Tobinai, Kensei ; Munakata, Wataru ; Yamauchi, Takeshi ; Kageyama, Akiko ; Yuasa, Miyuki ; Motoyama, Masaaki ; Tsunoda, Takeshi ; Hatake, Kiyohiko
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2015-07, Vol.106 (7), p.896-901
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ArticlesPeer ReviewedFull Text
Fulminant type I diabetes mellitus associated with nivolumab in a patient with relapsed classical Hodgkin lymphoma
Author / Creator:Munakata, Wataru ; Ohashi, Ken ; Yamauchi, Nobuhiko ; Tobinai, Kensei
Publisher:Tokyo: Springer Japan
Journal title:International journal of hematology, 2017-03, Vol.105 (3), p.383-386
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Epidemiological and clinical features of adult T‐cell leukemia–lymphoma in Japan, 2010–2011: A nationwide survey
Author / Creator:Nosaka, Kisato ; Iwanaga, Masako ; Imaizumi, Yoshitaka ; Ishitsuka, Kenji ; Ishizawa, Kenichi ; Ishida, Yoji ; Amano, Masahiro ; Ishida, Takashi ; Uike, Naokuni ; Utsunomiya, Atae ; Ohshima, Koichi ; Kawai, Kazuhiro ; Tanaka, Junji ; Tokura, Yoshiki ; Tobinai, Kensei ; Watanabe, Toshiki ; Uchimaru, Kaoru ; Tsukasaki, Kunihiro
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2017-12, Vol.108 (12), p.2478-2486
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Phase II study of E7777 in Japanese patients with relapsed/refractory peripheral and cutaneous T‐cell lymphoma
Author / Creator:Kawai, Hidetsugu ; Ando, Kiyoshi ; Maruyama, Dai ; Yamamoto, Kazuhito ; Kiyohara, Eiji ; Terui, Yasuhito ; Fukuhara, Noriko ; Miyagaki, Tomomitsu ; Tokura, Yoshiki ; Sakata‐Yanagimoto, Mamiko ; Igarashi, Tadahiko ; Kuroda, Junya ; Fujita, Jiro ; Uchida, Toshiki ; Ishikawa, Takayuki ; Yonekura, Kentaro ; Kato, Koji ; Nakanishi, Tadashi ; Nakai, Kenya ; Matsunaga, Risa ; Tobinai, Kensei
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2021-06, Vol.112 (6), p.2426-2435
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Prognosis of patients with adult T‐cell leukemia/lymphoma in Japan: A nationwide hospital‐based study
Author / Creator:Imaizumi, Yoshitaka ; Iwanaga, Masako ; Nosaka, Kisato ; Ishitsuka, Kenji ; Ito, Shigeki ; Amano, Masahiro ; Ishida, Takashi ; Uike, Naokuni ; Ohshima, Koichi ; Tanaka, Junji ; Tokura, Yoshiki ; Tobinai, Kensei ; Watanabe, Toshiki ; Uchimaru, Kaoru ; Tsukasaki, Kunihiro ; Takaori, Akifumi ; Hishizawa, Masakatsu ; Kitanaka, Akira ; Takami, Akiyoshi ; Ito, Asahi ; Yonekura, Kentaro ; Mugitani, Atsuko ; Kato, Chiaki ; Ogawa, Daisuke ; Tsuruta, Daisuke ; Ohtsuka, Eiichi ; Saburi, Yoshio ; Kazuyasu, Fujii ; Yoshimitsu, Makoto ; Matsubara, Fujio ; Nakamura, Fumihiko ; Sugaya, Makoto ; Kobayashi, Hajime ; Heizan, Hideho ; Fuse, Hiroe ; Shibayama, Hirohiko ; Yamaguchi, Hiroki ; Ishikawa, Hiroshi ; Yoshida, Shinichiro ; Kawano, Hiroshi ; Kazama, Hiroshi ; Yamasaki, Hiroshi ; Kuroda, Hiroyuki ; Yamada, Michiko ; Choi, Ilseung ; Uike, Naokuni ; Miyashita, Kaname ; Saigo, Katsuyasu ; Ohshiro, Kazuiku ; Tatsuno, Kazuki ; Ono, Takaaki ; Sugimoto, Keiji ; Etoh, Kenichiro ; Koga, Monji ; Narukawa, Kensuke ; Uozumi, Kimiharu ; Nagai, Koichi ; Adachi, Koji ; Motokura, Toru ; Izutsu, Koji ; Kato, Koji ; Nagafuji, Koji ; Yuge, Masaaki ; Miyahara, Masaharu ; Higuchi, Masakazu ; Hayashi, Masaki ; Iino, Masaki ; Makita, Masanori ; Shibano, Masaru ; Ito, Masato ; Saito, Masato ; Koike, Michiaki ; Hidaka, Michihiro ; Kurosawa, Mitsutoshi ; Fukazawa, Motoharu ; Shindo, Motohiro ; Takenaka, Motoi ; Kobayashi, Naoki ; Tominaga, Nobuhiko ; Fukuhara, Noriko ; Sakai, Rika ; Nawata, Ryohei ; Iyama, Satoshi ; Yamasaki, Satoshi ; Nakachi, Sawako ; Chiba, Shigeru ; Rai, Shinya ; Okada, Takahiro ; Inozume, Takashi ; Ikezoe, Takayuki ; Fujimoto, Takeshi ; Kaji, Tatsuya ; Myojo, Tomohiro ; Takahashi, Toru ; Nakayama, Toshiyuki ; Kato, Yoshiyasu ; Kobayashi, Yukio ; Moriuchi, Yukiyoshi ; Ogata, Yuko ; Katayama, Yuta
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2020-12, Vol.111 (12), p.4567-4580
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Multicenter phase II study of nivolumab in Japanese patients with relapsed or refractory classical Hodgkin lymphoma
Author / Creator:Maruyama, Dai ; Hatake, Kiyohiko ; Kinoshita, Tomohiro ; Fukuhara, Noriko ; Choi, Ilseung ; Taniwaki, Masafumi ; Ando, Kiyoshi ; Terui, Yasuhito ; Higuchi, Yusuke ; Onishi, Yasushi ; Abe, Yasunobu ; Kobayashi, Tsutomu ; Shirasugi, Yukari ; Tobinai, Kensei
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2017-05, Vol.108 (5), p.1007-1012
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E7777 in Japanese patients with relapsed/refractory peripheral and cutaneous T‐cell lymphoma: A phase I study
Author / Creator:Ohmachi, Ken ; Ando, Kiyoshi ; Ogura, Michinori ; Uchida, Toshiki ; Tobinai, Kensei ; Maruyama, Dai ; Namiki, Masayuki ; Nakanishi, Tadashi
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2018-03, Vol.109 (3), p.794-802
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Frontline bortezomib, rituximab, cyclophosphamide, doxorubicin, and prednisone (VR-CAP) versus rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) in transplantation-ineligi...
Author / Creator:Robak, Tadeusz, Prof ; Jin, Jie, MD ; Pylypenko, Halyna, MD ; Verhoef, Gregor, Prof ; Siritanaratkul, Noppadol, MD ; Drach, Johannes, MD ; Raderer, Markus, MD ; Mayer, Jiri, MD ; Pereira, Juliana, MD ; Tumyan, Gayane, MD ; Okamoto, Rumiko, MD ; Nakahara, Susumu, MD ; Hu, Peter, PhD ; Appiani, Carlos, MD ; Nemat, Sepideh, MD ; Cavalli, Franco, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2018-11, Vol.19 (11), p.1449-1458
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CDKN1C‐mediated growth inhibition by an EZH1/2 dual inhibitor overcomes resistance of mantle cell lymphoma to ibrutinib
Author / Creator:Kagiyama, Yuki ; Fujita, Shuhei ; Shima, Yutaka ; Yamagata, Kazutsune ; Katsumoto, Takuo ; Nakagawa, Makoto ; Honma, Daisuke ; Adachi, Nobuaki ; Araki, Kazushi ; Kato, Ayako ; Inaki, Koichiro ; Ono, Yoshimasa ; Fukuhara, Suguru ; Kobayashi, Yukio ; Tobinai, Kensei ; Kitabayashi, Issay
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2021-06, Vol.112 (6), p.2314-2324
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Valemetostat monotherapy in patients with relapsed or refractory non-Hodgkin lymphoma: a first-in-human, multicentre, open-label, single-arm, phase 1 study
Author / Creator:Maruyama, Dai, MD ; Jacobsen, Eric, MD ; Porcu, Pierluigi, Prof ; Allen, Pamela, MD ; Ishitsuka, Kenji, Prof ; Kusumoto, Shigeru, MD ; Narita, Tomoko, MD ; Tobinai, Kensei, MD ; Foss, Francine, Prof ; Tsukasaki, Kunihiro, Prof ; Feldman, Tatyana, MD ; Imaizumi, Yoshitaka, MD ; Izutsu, Koji, MD ; Morishima, Satoko, MD ; Yamauchi, Nobuhiko, MD ; Yuda, Junichiro, MD ; Brammer, Jonathan E, MD ; Kawamata, Toyotaka, MD ; Ruan, Jia, Prof ; Nosaka, Kisato, MD ; Utsunomiya, Atae, MD ; Wang, Jie, MD ; Zain, Jasmine, Prof ; Kakurai, Yasuyuki, PhD ; Yamauchi, Hideyuki, MSc ; Hizukuri, Yoshiyuki, PhD ; Biserna, Noha, MSc ; Tachibana, Masaya, PhD ; Inoue, Ai, MD ; Horwitz, Steven M, MD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2024-12, Vol.25 (12), p.1589-1601
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Showing 1 to 20 of 185 results

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Targeting EZH2 with tazemetostat

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Rituximab plus Lenalidomide in Advanced Untreated Follicular Lymphoma

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Mogamulizumab versus vorinostat in previously treated cutaneous T-cell lymphoma (MAVORIC): an international, open-label, randomised, controlled phase 3 trial

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Clinical development of anti‐CD19 chimeric antigen receptor T‐cell therapy for B‐cell non‐Hodgkin lymphoma

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Brentuximab vedotin with chemotherapy for CD30-positive peripheral T-cell lymphoma (ECHELON-2): a global, double-blind, randomised, phase 3 trial

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Nationwide claims database analysis of treatment patterns, costs and survival of Japanese patients with diffuse large B-cell lymphoma

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Oral histone deacetylase inhibitor tucidinostat (HBI‐8000) in patients with relapsed or refractory adult T‐cell leukemia/lymphoma: Phase IIb results

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Phase I study of tirabrutinib (ONO‐4059/GS‐4059) in patients with relapsed or refractory B‐cell malignancies in Japan

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Mogamulizumab for relapsed adult T‐cell leukemia–lymphoma: Updated follow‐up analysis of phase I and II studies

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Phase 1 study of tazemetostat in Japanese patients with relapsed or refractory B‐cell lymphoma

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Phase I study of OPB‐51602, an oral inhibitor of signal transducer and activator of transcription 3, in patients with relapsed/refractory hematological malignancies

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Fulminant type I diabetes mellitus associated with nivolumab in a patient with relapsed classical Hodgkin lymphoma

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Epidemiological and clinical features of adult T‐cell leukemia–lymphoma in Japan, 2010–2011: A nationwide survey

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Phase II study of E7777 in Japanese patients with relapsed/refractory peripheral and cutaneous T‐cell lymphoma

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Prognosis of patients with adult T‐cell leukemia/lymphoma in Japan: A nationwide hospital‐based study

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Multicenter phase II study of nivolumab in Japanese patients with relapsed or refractory classical Hodgkin lymphoma

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E7777 in Japanese patients with relapsed/refractory peripheral and cutaneous T‐cell lymphoma: A phase I study

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Frontline bortezomib, rituximab, cyclophosphamide, doxorubicin, and prednisone (VR-CAP) versus rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) in transplantation-ineligi...

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CDKN1C‐mediated growth inhibition by an EZH1/2 dual inhibitor overcomes resistance of mantle cell lymphoma to ibrutinib

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Valemetostat monotherapy in patients with relapsed or refractory non-Hodgkin lymphoma: a first-in-human, multicentre, open-label, single-arm, phase 1 study

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