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18 results for Tolvaptan+-+pharmacology

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ArticlesPeer ReviewedFull Text
Inactive structures of the vasopressin V2 receptor reveal distinct binding modes for Tolvaptan and Mambaquaretin toxin
Author / Creator:Fouillen, Aurélien ; Bous, Julien ; Couvineau, Pierre ; Orcel, Hélène ; Mary, Charline ; Lafleur, Lucie ; Pierre, Timothé ; Mendre, Christiane ; Gilles, Nicolas ; Schulte, Gunnar ; Granier, Sébastien ; Mouillac, Bernard
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-04, Vol.16 (1), p.3899-15, Article 3899
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Sensory primary cilium is a responsive cAMP microdomain in renal epithelia
Author / Creator:Sherpa, Rinzhin T. ; Mohieldin, Ashraf M. ; Pala, Rajasekharreddy ; Wachten, Dagmar ; Ostrom, Rennolds S. ; Nauli, Surya M.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-04, Vol.9 (1), p.6523-6523, Article 6523
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A Role for Both V1a and V2 Receptors in Renal Heat Stress Injury Amplified by Rehydration with Fructose
Author / Creator:García-Arroyo, Fernando E. ; Muñoz-Jiménez, Itzel ; Gonzaga, Guillermo ; Tapia, Edilia ; Osorio-Alonso, Horacio ; Roncal-Jiménez, Carlos A ; Iroz, Alison ; Vecchio, Mariacristina ; Reyes-García, Juan G. ; Johnson, Richard J ; Sánchez-Lozada, L Gabriela
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2019-11, Vol.20 (22), p.5764
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Tolvaptan activates the Nrf2/HO-1 antioxidant pathway through PERK phosphorylation
Author / Creator:Fujiki, Tamami ; Ando, Fumiaki ; Murakami, Kana ; Isobe, Kiyoshi ; Mori, Takayasu ; Susa, Koichiro ; Nomura, Naohiro ; Sohara, Eisei ; Rai, Tatemitsu ; Uchida, Shinichi
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-06, Vol.9 (1), p.9245-10, Article 9245
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Long-Term Effects of Tolvaptan in Autosomal Dominant Polycystic Kidney Disease: Predictors of Treatment Response and Safety over 6 Years of Continuous Therapy
Author / Creator:Yamazaki, Mai ; Kawano, Haruna ; Miyoshi, Miho ; Kimura, Tomoki ; Takahashi, Keiji ; Muto, Satoru ; Horie, Shigeo
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2024-02, Vol.25 (4), p.2088
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Autosomal-dominant polycystic kidney disease: tolvaptan use in adolescents and young adults with rapid progression
Author / Creator:Raina, Rupesh ; Chakraborty, Ronith ; DeCoy, Meredith E. ; Kline, Timothy
Publisher:New York: Nature Publishing Group US
Journal title:Pediatric research, 2021-03, Vol.89 (4), p.894-899
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Targeting the vasopressin type-2 receptor for renal cell carcinoma therapy
Author / Creator:Sinha, Sonali ; Dwivedi, Nidhi ; Tao, Shixin ; Jamadar, Abeda ; Kakade, Vijayakumar R. ; Neil, Maura O’ ; Weiss, Robert H. ; Enders, Jonathan ; Calvet, James P. ; Thomas, Sufi M. ; Rao, Reena
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2020-02, Vol.39 (6), p.1231-1245
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A metabolically stable apelin-17 analog decreases AVP-induced antidiuresis and improves hyponatremia
Author / Creator:Flahault, Adrien ; Girault-Sotias, Pierre-Emmanuel ; Keck, Mathilde ; Alvear-Perez, Rodrigo ; De Mota, Nadia ; Estéoulle, Lucie ; Ramanoudjame, Sridévi M. ; Iturrioz, Xavier ; Bonnet, Dominique ; Llorens-Cortes, Catherine
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-01, Vol.12 (1), p.305-14, Article 305
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The Vasopressin Receptor Antagonist Tolvaptan Counteracts Tumor Growth in a Murine Xenograft Model of Small Cell Lung Cancer
Author / Creator:Naldi, Laura ; Fibbi, Benedetta ; Polvani, Simone ; Cirillo, Chiara ; Pasella, Francesca ; Bartolini, Francesca ; Romano, Francesca ; Fanelli, Alessandra ; Peri, Alessandro ; Marroncini, Giada
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2024-08, Vol.25 (15), p.8402
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Prioritized polycystic kidney disease drug targets and repurposing candidates from pre-cystic and cystic mouse Pkd2 model gene expression reversion
Author / Creator:Wilk, Elizabeth J. ; Howton, Timothy C. ; Fisher, Jennifer L. ; Oza, Vishal H. ; Brownlee, Ryan T. ; McPherson, Kasi C. ; Cleary, Hannah L. ; Yoder, Bradley K. ; George, James F. ; Mrug, Michal ; Lasseigne, Brittany N.
Publisher:England: BioMed Central
Journal title:Molecular medicine (Cambridge, Mass.), 2023-05, Vol.29 (1), p.67-21, Article 67
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Risk factors for sodium overcorrection in non-hypovolemic hyponatremia patients treated with tolvaptan
Author / Creator:Kim, Yukyung ; Lee, Nari ; Lee, Kyung Eun ; Gwak, Hye Sun
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:European journal of clinical pharmacology, 2020-05, Vol.76 (5), p.723-729
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Characterization of five novel vasopressin V2 receptor mutants causing nephrogenic diabetes insipidus reveals a role of tolvaptan for M272R-V2R mutation
Author / Creator:Prosperi, Federica ; Suzumoto, Yoko ; Marzuillo, Pierluigi ; Costanzo, Vincenzo ; Jelen, Sabina ; Iervolino, Anna ; Guarino, Stefano ; La Manna, Angela ; Miraglia Del Giudice, Emanuele ; Perna, Alessandra F. ; Zacchia, Miriam ; Cordat, Emmanuelle ; Capasso, Giovambattista ; Trepiccione, Francesco
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-10, Vol.10 (1), p.16383, Article 16383
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Renal cyst growth is attenuated by a combination treatment of tolvaptan and pioglitazone, while pioglitazone treatment alone is not effective
Author / Creator:Kanhai, Anish A. ; Bange, Hester ; Verburg, Lotte ; Dijkstra, Kyra L. ; Price, Leo S. ; Peters, Dorien J. M. ; Leonhard, Wouter N.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-02, Vol.10 (1), p.1672-1672, Article 1672
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Response criteria of tolvaptan for the treatment of hepatic edema
Author / Creator:Hiramine, Yasunari ; Uojima, Haruki ; Nakanishi, Hiroyuki ; Hiramatsu, Akira ; Iwamoto, Takuya ; Kimura, Mutsuumi ; Kawaratani, Hideto ; Terai, Shuji ; Yoshiji, Hitoshi ; Uto, Hirofumi ; Sakaida, Isao ; Izumi, Namiki ; Okita, Kiwamu ; Koike, Kazuhiko
Publisher:Tokyo: Springer Japan
Journal title:Journal of gastroenterology, 2018-02, Vol.53 (2), p.258-268
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Impact of serum albumin levels on the body fluid response to tolvaptan in chronic kidney disease patients
Author / Creator:Masuda, Takahiro ; Ohara, Ken ; Nagayama, Izumi ; Matsuoka, Ryo ; Murakami, Takuya ; Nakagawa, Saki ; Oka, Kentanro ; Asakura, Maki ; Igarashi, Yusuke ; Fukaya, Yukimura ; Miyazawa, Yasuharu ; Maeshima, Akito ; Akimoto, Tetsu ; Saito, Osamu ; Nagata, Daisuke
Publisher:Dordrecht: Springer Netherlands
Journal title:International urology and nephrology, 2019-09, Vol.51 (9), p.1623-1629
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Regulatory guidelines do not accurately predict tolvaptan and metabolite interactions at BCRP, OATP1B1, and OAT3 transporters
Author / Creator:Shoaf, Susan E. ; Bricmont, Patricia ; Repella Gordon, Jennifer
Publisher:United States: John Wiley & Sons, Inc
Journal title:Clinical and translational science, 2021-07, Vol.14 (4), p.1535-1542
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Protective effect of tolvaptan against cyclophosphamide‐induced nephrotoxicity in rat models
Author / Creator:El‐Shabrawy, Mohamed ; Mishriki, Amal ; Attia, Hisham ; Emad Aboulhoda, Basma ; Emam, Mohamed ; Wanas, Hanaa
Publisher:United States: John Wiley & Sons, Inc
Journal title:Pharmacology research & perspectives, 2020-10, Vol.8 (5), p.e00659-n/a
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Elevation of the serum liver enzyme levels during tolvaptan treatment in patients with autosomal dominant polycystic kidney disease (ADPKD)
Author / Creator:Makabe, Shiho ; Mochizuki, Toshio ; Mitobe, Michihiro ; Aoyama, Yumi ; Kataoka, Hiroshi ; Tsuchiya, Ken ; Nitta, Kosaku
Publisher:Singapore: Springer Singapore
Journal title:Clinical and experimental nephrology, 2018-10, Vol.22 (5), p.1079-1087
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Inactive structures of the vasopressin V2 receptor reveal distinct binding modes for Tolvaptan and Mambaquaretin toxin

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Sensory primary cilium is a responsive cAMP microdomain in renal epithelia

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A Role for Both V1a and V2 Receptors in Renal Heat Stress Injury Amplified by Rehydration with Fructose

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Tolvaptan activates the Nrf2/HO-1 antioxidant pathway through PERK phosphorylation

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Long-Term Effects of Tolvaptan in Autosomal Dominant Polycystic Kidney Disease: Predictors of Treatment Response and Safety over 6 Years of Continuous Therapy

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Autosomal-dominant polycystic kidney disease: tolvaptan use in adolescents and young adults with rapid progression

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Targeting the vasopressin type-2 receptor for renal cell carcinoma therapy

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A metabolically stable apelin-17 analog decreases AVP-induced antidiuresis and improves hyponatremia

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The Vasopressin Receptor Antagonist Tolvaptan Counteracts Tumor Growth in a Murine Xenograft Model of Small Cell Lung Cancer

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Prioritized polycystic kidney disease drug targets and repurposing candidates from pre-cystic and cystic mouse Pkd2 model gene expression reversion

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Risk factors for sodium overcorrection in non-hypovolemic hyponatremia patients treated with tolvaptan

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Characterization of five novel vasopressin V2 receptor mutants causing nephrogenic diabetes insipidus reveals a role of tolvaptan for M272R-V2R mutation

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Renal cyst growth is attenuated by a combination treatment of tolvaptan and pioglitazone, while pioglitazone treatment alone is not effective

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Response criteria of tolvaptan for the treatment of hepatic edema

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Impact of serum albumin levels on the body fluid response to tolvaptan in chronic kidney disease patients

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Regulatory guidelines do not accurately predict tolvaptan and metabolite interactions at BCRP, OATP1B1, and OAT3 transporters

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Protective effect of tolvaptan against cyclophosphamide‐induced nephrotoxicity in rat models

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Elevation of the serum liver enzyme levels during tolvaptan treatment in patients with autosomal dominant polycystic kidney disease (ADPKD)

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