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A randomized, placebo-controlled experimental medicine study of RIPK1 inhibitor GSK2982772 in patients with moderate to severe rheumatoid arthritis
Author / Creator:Weisel, Kathleen ; Berger, Scott ; Thorn, Katie ; Taylor, Peter C ; Peterfy, Charles ; Siddall, Hilary ; Tompson, Debra ; Wang, Susanne ; Quattrocchi, Emilia ; Burriss, Susan W ; Walter, Jochen ; Tak, Paul Peter
Publisher:England: BioMed Central Ltd
Journal title:Arthritis research & therapy, 2021-03, Vol.23 (1), p.85-12, Article 85
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Development of a Prototype, Once-Daily, Modified-Release Formulation for the Short Half-Life RIPK1 Inhibitor GSK2982772
Author / Creator:Tompson, Debra J. ; Whitaker, Mark ; Pan, Rennan ; Johnson, Geoffrey ; Fuller, Teresa ; McKenzie, Litza ; Zann, Vanessa ; Powell, Marcy ; Abbott-Banner, Kathy ; Hawkins, Simon
Publisher:New York: Springer US
Journal title:Pharmaceutical research, 2021-07, Vol.38 (7), p.1235-1245
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A randomised, placebo-controlled study of RIPK1 inhibitor GSK2982772 in patients with active ulcerative colitis
Author / Creator:Weisel, Kathy ; Scott, Nicola ; Berger, Scott ; Wang, Susanne ; Brown, Kurt ; Powell, Marcy ; Broer, Matthijs ; Watts, Clarissa ; Tompson, Debra J ; Burriss, Susan W ; Hawkins, Simon ; Abbott-Banner, Kathy ; Tak, Paul Peter
Publisher:England: BMJ Publishing Group Ltd
Journal title:BMJ open gastroenterology, 2021-08, Vol.8 (1), p.e000680
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Steady-state pharmacokinetic properties of a 24-hour prolonged-release formulation of ropinirole: Results of two randomized studies in patients with Parkinson's disease
Author / Creator:Tompson, Debra J., MSc ; Vearer, Deborah, MSc
Publisher:Belle Mead, NJ: EM Inc USA
Journal title:Clinical therapeutics, 2007-12, Vol.29 (12), p.2654-2666
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Randomized clinical study of safety, pharmacokinetics, and pharmacodynamics of RIPK1 inhibitor GSK2982772 in healthy volunteers
Author / Creator:Weisel, Kathleen ; Scott, Nicola E. ; Tompson, Debra J. ; Votta, Bartholomew J. ; Madhavan, Sujith ; Povey, Kat ; Wolstenholme, Allen ; Simeoni, Monica ; Rudo, Todd ; Richards‐Peterson, Lauren ; Sahota, Tarjinder ; Wang, J. Gene ; Lich, John ; Finger, Joshua ; Verticelli, Adeline ; Reilly, Michael ; Gough, Peter J. ; Harris, Philip A. ; Bertin, John ; Wang, Mei‐Lun
Publisher:United States: John Wiley and Sons Inc
Journal title:Pharmacology research & perspectives, 2017-12, Vol.5 (6), p.n/a
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Physiologically based pharmacokinetic modeling for development and applications of a virtual celiac disease population using felodipine as a model drug
Author / Creator:Salem, Farzaneh ; Nimavardi, Ali ; Mudunuru, Jennypher ; Tompson, Debra ; Bloomer, Jackie ; Turner, David B. ; Taskar, Kunal S.
Publisher:United States: John Wiley & Sons, Inc
Journal title:CPT: pharmacometrics and systems pharmacology, 2023-06, Vol.12 (6), p.808-820
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The Effects of Ethanol on the Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Ezogabine (Retigabine)
Author / Creator:Crean, Christopher S., MS, RAC ; Tompson, Debra J., MSc
Publisher:Bridgewater, NJ: EM Inc USA
Journal title:Clinical therapeutics, 2013, Vol.35 (1), p.87-93
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Inhibition of Receptor-Interacting Protein Kinase 1 in Chronic Plaque Psoriasis: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study
Author / Creator:Ludbrook, Valerie J. ; Budd, David C. ; Thorn, Katie ; Tompson, Debra ; Votta, Bartholomew J. ; Walker, Lucy ; Lee, Amy ; Chen, Xin ; Peppercorn, Amanda ; Loo, Wei Jing
Publisher:Cheshire: Springer Healthcare
Journal title:Dermatology and therapy, 2024-02, Vol.14 (2), p.489-504
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Efficacy and Tolerability Exposure–Response Relationship of Retigabine (Ezogabine) Immediate-Release Tablets in Patients With Partial-Onset Seizures
Author / Creator:Tompson, Debra J., MSc ; Crean, Christopher S., MS ; Reeve, Russell, PhD ; Berry, N. Seth, PharmD
Publisher:Bridgewater, NJ: EM Inc USA
Journal title:Clinical therapeutics, 2013-08, Vol.35 (8), p.1174-1185.e4
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Single and Multiple Dose Pharmacokinetics, Pharmacodynamics and Safety of the Novel Lipoprotein-Associated Phospholipase A2 Enzyme Inhibitor Darapladib in Healthy Chinese Subjects: An Open Label Phase...
Author / Creator:Hu, Chaoying ; Tompson, Debra ; Magee, Mindy ; Chen, Qian ; Liu, Yan Mei ; Zhu, Wenjing ; Zhao, Hongxin ; Gross, Annette S ; Liu, Yun
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-10, Vol.10 (10), p.e0139862-e0139862
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Lack of effect of ezogabine/retigabine on the pharmacokinetics of digoxin in healthy individuals: results from a drug-drug interaction study
Author / Creator:Tompson, Debra J ; Crean, Christopher S ; Buraglio, Mauro ; Arumugham, Thangam
Publisher:New Zealand: Dove Medical Press Limited
Journal title:Clinical pharmacology: advances and applications, 2014-01, Vol.6 (default), p.149-159
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ArticlesPeer ReviewedFull Text
Randomized clinical study of safety, pharmacokinetics, and pharmacodynamics of RIPK 1 inhibitor GSK 2982772 in healthy volunteers
Author / Creator:Weisel, Kathleen ; Scott, Nicola E. ; Tompson, Debra J. ; Votta, Bartholomew J. ; Madhavan, Sujith ; Povey, Kat ; Wolstenholme, Allen ; Simeoni, Monica ; Rudo, Todd ; Richards‐Peterson, Lauren ; Sahota, Tarjinder ; Wang, J. Gene ; Lich, John ; Finger, Joshua ; Verticelli, Adeline ; Reilly, Michael ; Gough, Peter J. ; Harris, Philip A. ; Bertin, John ; Wang, Mei‐Lun
Publisher:Bognor Regis: John Wiley & Sons, Inc
Journal title:Pharmacology research & perspectives, 2017-12, Vol.5 (6)
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Lesion remyelinating activity of GSK239512 versus placebo in patients with relapsing-remitting multiple sclerosis: a randomised, single-blind, phase II study
Author / Creator:Schwartzbach, Caryl J. ; Grove, Richard A. ; Brown, Robert ; Tompson, Debra ; Then Bergh, Florian ; Arnold, Douglas L.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Journal of neurology, 2017-02, Vol.264 (2), p.304-315
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ArticlesPeer ReviewedFull Text
Development of a Once-Daily Modified-Release Formulation for the Short Half-Life RIPK1 Inhibitor GSK2982772 using DiffCORE Technology
Author / Creator:Tompson, Debra ; Whitaker, Mark ; Pan, Rennan ; Johnson, Geoffrey ; Fuller, Teresa ; Zann, Vanessa ; McKenzie, Litza ; Abbott-Banner, Kathy ; Hawkins, Simon ; Powell, Marcy
Publisher:New York: Springer US
Journal title:Pharmaceutical research, 2022-01, Vol.39 (1), p.153-165
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ArticlesPeer ReviewedFull Text
Single and Multiple Dose Pharmacokinetics, Pharmacodynamics and Safety of the Novel Lipoprotein-Associated Phospholipase A.sub.2 Enzyme Inhibitor Darapladib in Healthy Chinese Subjects: An Open Label...
Author / Creator:Hu, Chaoying ; Tompson, Debra ; Magee, Mindy ; Chen, Qian ; Liu, Yan Mei ; Zhu, Wenjing ; Zhao, Hongxin ; Gross, Annette S ; Liu, Yun
Publisher:Public Library of Science
Journal title:PloS one, 2015-10, Vol.10 (10)
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ReportsFull Text
A randomized, placebo-controlled experimental medicine study of RIPK1 inhibitor GSK2982772 in patients with moderate to severe rheumatoid arthritis
Author / Creator:Weisel, Kathleen ; Berger, Scott ; Thorn, Katie ; Taylor, Peter C ; Peterfy, Charles ; Siddall, Hilary ; Tompson, Debra ; Wang, Susanne ; Quattrocchi, Emilia ; Burriss, Susan W ; Walter, Jochen ; Tak, Paul Peter
Publisher:BioMed Central Ltd
Journal title:Arthritis Research & Therapy, 2021, Vol.23 (1)
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ReportsFull Text
Lack of effect of ezogabine/retigabine on the pharmacokinetics of digoxin in healthy individuals: results from a drug--drug interaction study
Author / Creator:Tompson, Debra J ; Crean, Christopher S ; Buraglio, Mauro ; Arumugham, Thangam
Publisher:Dove Medical Press Limited
Journal title:Clinical Pharmacology: Advances and Applications, 2014, Vol.6, p.149
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ReportsFull Text
Single and Multiple Dose Pharmacokinetics, Pharmacodynamics and Safety of the Novel Lipoprotein-Associated Phospholipase A.sub.2 Enzyme Inhibitor Darapladib in Healthy Chinese Subjects: An Open Label...
Author / Creator:Hu, Chaoying ; Tompson, Debra ; Magee, Mindy ; Chen, Qian ; Liu, Yan Mei ; Zhu, Wenjing ; Zhao, Hongxin ; Gross, Annette S ; Liu, Yun
Publisher:Public Library of Science
Journal title:PLoS ONE, 2015, Vol.10 (10)
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A randomized, placebo-controlled experimental medicine study of RIPK1 inhibitor GSK2982772 in patients with moderate to severe rheumatoid arthritis

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Development of a Prototype, Once-Daily, Modified-Release Formulation for the Short Half-Life RIPK1 Inhibitor GSK2982772

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A randomised, placebo-controlled study of RIPK1 inhibitor GSK2982772 in patients with active ulcerative colitis

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Steady-state pharmacokinetic properties of a 24-hour prolonged-release formulation of ropinirole: Results of two randomized studies in patients with Parkinson's disease

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Randomized clinical study of safety, pharmacokinetics, and pharmacodynamics of RIPK1 inhibitor GSK2982772 in healthy volunteers

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Physiologically based pharmacokinetic modeling for development and applications of a virtual celiac disease population using felodipine as a model drug

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The Effects of Ethanol on the Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Ezogabine (Retigabine)

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Inhibition of Receptor-Interacting Protein Kinase 1 in Chronic Plaque Psoriasis: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study

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Efficacy and Tolerability Exposure–Response Relationship of Retigabine (Ezogabine) Immediate-Release Tablets in Patients With Partial-Onset Seizures

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Single and Multiple Dose Pharmacokinetics, Pharmacodynamics and Safety of the Novel Lipoprotein-Associated Phospholipase A2 Enzyme Inhibitor Darapladib in Healthy Chinese Subjects: An Open Label Phase...

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Lack of effect of ezogabine/retigabine on the pharmacokinetics of digoxin in healthy individuals: results from a drug-drug interaction study

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Randomized clinical study of safety, pharmacokinetics, and pharmacodynamics of RIPK 1 inhibitor GSK 2982772 in healthy volunteers

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Lesion remyelinating activity of GSK239512 versus placebo in patients with relapsing-remitting multiple sclerosis: a randomised, single-blind, phase II study

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Development of a Once-Daily Modified-Release Formulation for the Short Half-Life RIPK1 Inhibitor GSK2982772 using DiffCORE Technology

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Single and Multiple Dose Pharmacokinetics, Pharmacodynamics and Safety of the Novel Lipoprotein-Associated Phospholipase A.sub.2 Enzyme Inhibitor Darapladib in Healthy Chinese Subjects: An Open Label...

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A randomized, placebo-controlled experimental medicine study of RIPK1 inhibitor GSK2982772 in patients with moderate to severe rheumatoid arthritis

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Lack of effect of ezogabine/retigabine on the pharmacokinetics of digoxin in healthy individuals: results from a drug--drug interaction study

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Single and Multiple Dose Pharmacokinetics, Pharmacodynamics and Safety of the Novel Lipoprotein-Associated Phospholipase A.sub.2 Enzyme Inhibitor Darapladib in Healthy Chinese Subjects: An Open Label...

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