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ArticlesPeer ReviewedFull Text
NK-92: an ‘off-the-shelf therapeutic’ for adoptive natural killer cell-based cancer immunotherapy
Author / Creator:Suck, Garnet ; Odendahl, Marcus ; Nowakowska, Paulina ; Seidl, Christian ; Wels, Winfried S. ; Klingemann, Hans G. ; Tonn, Torsten
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Cancer Immunology, Immunotherapy, 2016-04, Vol.65 (4), p.485-492
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Epitopes of MUC1 Tandem Repeats in Cancer as Revealed by Antibody Crystallography: Toward Glycopeptide Signature-Guided Therapy
Author / Creator:Zhou, Dapeng ; Xu, Lan ; Huang, Wei ; Tonn, Torsten
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2018-05, Vol.23 (6), p.1326
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CD19‐CAR engineered NK‐92 cells are sufficient to overcome NK cell resistance in B‐cell malignancies
Author / Creator:Romanski, Annette ; Uherek, Christoph ; Bug, Gesine ; Seifried, Erhard ; Klingemann, Hans ; Wels, Winfried S. ; Ottmann, Oliver G. ; Tonn, Torsten
Publisher:England: John Wiley and Sons Inc
Journal title:Journal of cellular and molecular medicine, 2016-07, Vol.20 (7), p.1287-1294
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Clinical grade manufacturing of genetically modified, CAR-expressing NK-92 cells for the treatment of ErbB2-positive malignancies
Author / Creator:Nowakowska, Paulina ; Romanski, Annette ; Miller, Nicole ; Odendahl, Marcus ; Bonig, Halvard ; Zhang, Congcong ; Seifried, Erhard ; Wels, Winfried S ; Tonn, Torsten
Publisher:Heidelberg: Springer Nature B.V
Journal title:Cancer immunology, immunotherapy, 2018-01, Vol.67 (1), p.25-38
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Selection and expansion of natural killer cells for NK cell-based immunotherapy
Author / Creator:Becker, Petra S. A. ; Suck, Garnet ; Nowakowska, Paulina ; Ullrich, Evelyn ; Seifried, Erhard ; Bader, Peter ; Tonn, Torsten ; Seidl, Christian
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Cancer Immunology, Immunotherapy, 2016-04, Vol.65 (4), p.477-484
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Selective Inhibition of Tumor Growth by Clonal NK Cells Expressing an ErbB2/HER2-Specific Chimeric Antigen Receptor
Author / Creator:Schönfeld, Kurt ; Sahm, Christiane ; Zhang, Congcong ; Naundorf, Sonja ; Brendel, Christian ; Odendahl, Marcus ; Nowakowska, Paulina ; Bönig, Halvard ; Köhl, Ulrike ; Kloess, Stephan ; Köhler, Sylvia ; Holtgreve-Grez, Heidi ; Jauch, Anna ; Schmidt, Manfred ; Schubert, Ralf ; Kühlcke, Klaus ; Seifried, Erhard ; Klingemann, Hans G ; Rieger, Michael A ; Tonn, Torsten ; Grez, Manuel ; Wels, Winfried S
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2015-02, Vol.23 (2), p.330-338
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“UniCAR”-modified off-the-shelf NK-92 cells for targeting of GD2-expressing tumour cells
Author / Creator:Mitwasi Nicola ; Feldmann Anja ; Arndt, Claudia ; Koristka Stefanie ; Berndt, Nicole ; Jureczek Justyna ; Loureiro, Liliana R ; Bergmann Ralf ; Domokos, Máthé ; Hegedüs Nikolett ; Kovács Tibor ; Zhang Congcong ; Oberoi Pranav ; Jäger Elke ; Seliger, Barbara ; Rössig Claudia ; Temme Achim ; Eitler Jiri ; Tonn Torsten ; Schmitz, Marc ; Hassel, Jessica C ; Jäger, Dirk ; Wels, Winfried S ; Bachmann, Michael
Publisher:London: Nature Publishing Group
Journal title:Scientific reports, 2020-02, Vol.10 (1)
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C/EBPβ-dependent autophagy inhibition hinders NK cell function in cancer
Author / Creator:Portale, Federica ; Carriero, Roberta ; Iovino, Marta ; Kunderfranco, Paolo ; Pandini, Marta ; Marelli, Giulia ; Morina, Nicolò ; Lazzeri, Massimo ; Casale, Paolo ; Colombo, Piergiuseppe ; De Simone, Gabriele ; Camisaschi, Chiara ; Lugli, Enrico ; Basso, Gianluca ; Cibella, Javier ; Marchini, Sergio ; Bordi, Matteo ; Meregalli, Greta ; Garbin, Anna ; Dambra, Monica ; Magrini, Elena ; Rackwitz, Wiebke ; Cecconi, Francesco ; Corbelli, Alessandro ; Fiordaliso, Fabio ; Eitler, Jiri ; Tonn, Torsten ; Di Mitri, Diletta
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-11, Vol.15 (1), p.10343-21, Article 10343
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Transcoronary Transplantation of Progenitor Cells after Myocardial Infarction
Author / Creator:Assmus, Birgit ; Honold, Jörg ; Schächinger, Volker ; Britten, Martina B ; Fischer-Rasokat, Ulrich ; Lehmann, Ralf ; Teupe, Claudius ; Pistorius, Katrin ; Martin, Hans ; Abolmaali, Nasreddin D ; Tonn, Torsten ; Dimmeler, Stefanie ; Zeiher, Andreas M
Publisher:Boston, MA: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2006-09, Vol.355 (12), p.1222-1232
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ArticlesPeer ReviewedFull Text
Intracoronary Bone Marrow–Derived Progenitor Cells in Acute Myocardial Infarction
Author / Creator:Schächinger, Volker ; Erbs, Sandra ; Elsässer, Albrecht ; Haberbosch, Werner ; Hambrecht, Rainer ; Hölschermann, Hans ; Yu, Jiangtao ; Corti, Roberto ; Mathey, Detlef G ; Hamm, Christian W ; Süselbeck, Tim ; Assmus, Birgit ; Tonn, Torsten ; Dimmeler, Stefanie ; Zeiher, Andreas M
Publisher:Boston, MA: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2006-09, Vol.355 (12), p.1210-1221
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ArticlesPeer ReviewedFull Text
Inability of granule polarization by NK cells defines tumor resistance and can be overcome by CAR or ADCC mediated targeting
Author / Creator:Eitler, Jiri ; Wotschel, Natalie ; Miller, Nicole ; Boissel, Laurent ; Klingemann, Hans G ; Wels, Winfried ; Tonn, Torsten
Publisher:England: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2021-01, Vol.9 (1), p.e001334
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Blood-based detection of MMP11 as a marker of prostate cancer progression regulated by the ALDH1A1-TGF-β1 signaling mechanism
Author / Creator:Gorodetska, Ielizaveta ; Lukiyanchuk, Vasyl ; Gawin, Marta ; Sliusar, Myroslava ; Linge, Annett ; Lohaus, Fabian ; Hölscher, Tobias ; Erdmann, Kati ; Fuessel, Susanne ; Borkowetz, Angelika ; Wojakowska, Anna ; Fochtman, Daniel ; Reardon, Mark ; Choudhury, Ananya ; Antonelli, Yasmin ; Leal-Egaña, Aldo ; Köseer, Ayse Sedef ; Kahya, Uğur ; Püschel, Jakob ; Petzold, Andrea ; Klusa, Daria ; Peitzsch, Claudia ; Kronstein-Wiedemann, Romy ; Tonn, Torsten ; Marczak, Lukasz ; Thomas, Christian ; Widłak, Piotr ; Pietrowska, Monika ; Krause, Mechthild ; Dubrovska, Anna
Publisher:England: BioMed Central
Journal title:Journal of experimental & clinical cancer research, 2025-03, Vol.44 (1), p.105-25, Article 105
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ArticlesPeer ReviewedFull Text
Expression of a CD20-specific chimeric antigen receptor enhances cytotoxic activity of NK cells and overcomes NK-resistance of lymphoma and leukemia cells
Author / Creator:Müller, Tina ; Uherek, Christoph ; Maki, Guitta ; Chow, Kai Uwe ; Schimpf, Annemarie ; Klingemann, Hans-Georg ; Tonn, Torsten ; Wels, Winfried S.
Publisher:Berlin/Heidelberg: Springer-Verlag
Journal title:Cancer Immunology, Immunotherapy, 2008-03, Vol.57 (3), p.411-423
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CAR-mediated targeting of NK cells overcomes tumor immune escape caused by ICAM-1 downregulation
Author / Creator:Eitler, Jiri ; Rackwitz, Wiebke ; Wotschel, Natalie ; Gudipati, Venugopal ; Murali Shankar, Nivedha ; Sidorenkova, Anastasia ; Huppa, Johannes B ; Ortiz-Montero, Paola ; Opitz, Corinna ; Künzel, Stephan R ; Michen, Susanne ; Temme, Achim ; Loureiro, Liliana Rodrigues ; Feldmann, Anja ; Bachmann, Michael ; Boissel, Laurent ; Klingemann, Hans ; Wels, Winfried S ; Tonn, Torsten
Publisher:England: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2024-02, Vol.12 (2), p.e008155
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EV-3, an endogenous human erythropoietin isoform with distinct functional relevance
Author / Creator:Bonnas, Christel ; Wüstefeld, Liane ; Winkler, Daniela ; Kronstein-Wiedemann, Romy ; Dere, Ekrem ; Specht, Katja ; Boxberg, Melanie ; Tonn, Torsten ; Ehrenreich, Hannelore ; Stadler, Herbert ; Sillaber, Inge
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-06, Vol.7 (1), p.3684-15, Article 3684
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Serum immune checkpoint profiling identifies soluble CD40 as a biomarker for pancreatic cancer
Author / Creator:Digomann, David ; Heiduk, Max ; Reiche, Charlotte ; Glück, Jessica ; Kahlert, Christoph ; Mirtschink, Peter ; Klimova, Anna ; Bösch, Florian ; Tonn, Torsten ; Gaedcke, Jochen ; Ghadimi, Michael ; Weitz, Jürgen ; Seifert, Lena ; Seifert, Adrian M.
Publisher:London: Nature Publishing Group UK
Journal title:NPJ precision oncology, 2023-10, Vol.7 (1), p.104-9, Article 104
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442-Q CAR-mediated targeting of NK cells overcomes tumor immune escape caused by ICAM-1 downregulation
Author / Creator:Eitler, Jiri ; Rackwitz, Wiebke ; Wotschel, Natalie ; Gudipati, Venugopal ; Huppa, Johannes ; Montero, Paola Ortiz ; Boissel, Laurent ; Klingemann, Hans ; Wels, Winfried ; Tonn, Torsten
Publisher:London: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 2), p.A1801-A1801
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Chemical Chaperones Improve Protein Secretion and Rescue Mutant Factor VIII in Mice with Hemophilia A
Author / Creator:Roth, Stefanie D. ; Schüttrumpf, Jörg ; Milanov, Peter ; Abriss, Daniela ; Ungerer, Christopher ; Quade-Lyssy, Patricia ; Simpson, Jeremy C. ; Pepperkok, Rainer ; Seifried, Erhard ; Tonn, Torsten
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-09, Vol.7 (9), p.e44505
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Quality of life and metabolic outcomes after total pancreatectomy and simultaneous islet autotransplantation
Author / Creator:Ludwig, Stefan ; Distler, Marius ; Schubert, Undine ; Schmid, Janine ; Thies, Henriette ; Welsch, Thilo ; Hempel, Sebastian ; Tonn, Torsten ; Weitz, Jürgen ; Bornstein, Stefan R. ; Ludwig, Barbara
Publisher:London: Nature Publishing Group UK
Journal title:Communications medicine, 2022-03, Vol.2 (1), p.24-7, Article 24
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Hybrid Immunity Protects against Antibody Fading after SARS-CoV-2mRNA Vaccination in Kidney Transplant Recipients, Dialysis Patients, and Medical Personnel: 9 Months Data from the Prospective, Observa...
Author / Creator:Stumpf, Julian ; Siepmann, Torsten ; Schwöbel, Jörg ; Karger, Claudia ; Lindner, Tom H. ; Faulhaber-Walter, Robert ; Langer, Torsten ; Escher, Katja ; Anding-Rost, Kirsten ; Seidel, Harald ; Hüther, Jan ; Pistrosch, Frank ; Martin, Heike ; Schewe, Jens ; Stehr, Thomas ; Meistring, Frank ; Paliege, Alexander ; Schneider, Daniel ; Steglich, Anne ; Gembardt, Florian ; Kessel, Friederike ; Kröger, Hannah ; Arndt, Patrick ; Sradnick, Jan ; Frank, Kerstin ; Klimova, Anna ; Mauer, René ; Roeder, Ingo ; Tonn, Torsten ; Hugo, Christian
Publisher:Switzerland: MDPI AG
Journal title:Vaccines (Basel), 2024-07, Vol.12 (7), p.801
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NK-92: an ‘off-the-shelf therapeutic’ for adoptive natural killer cell-based cancer immunotherapy

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Epitopes of MUC1 Tandem Repeats in Cancer as Revealed by Antibody Crystallography: Toward Glycopeptide Signature-Guided Therapy

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CD19‐CAR engineered NK‐92 cells are sufficient to overcome NK cell resistance in B‐cell malignancies

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Clinical grade manufacturing of genetically modified, CAR-expressing NK-92 cells for the treatment of ErbB2-positive malignancies

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Selection and expansion of natural killer cells for NK cell-based immunotherapy

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Selective Inhibition of Tumor Growth by Clonal NK Cells Expressing an ErbB2/HER2-Specific Chimeric Antigen Receptor

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“UniCAR”-modified off-the-shelf NK-92 cells for targeting of GD2-expressing tumour cells

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C/EBPβ-dependent autophagy inhibition hinders NK cell function in cancer

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Transcoronary Transplantation of Progenitor Cells after Myocardial Infarction

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Intracoronary Bone Marrow–Derived Progenitor Cells in Acute Myocardial Infarction

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Inability of granule polarization by NK cells defines tumor resistance and can be overcome by CAR or ADCC mediated targeting

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Blood-based detection of MMP11 as a marker of prostate cancer progression regulated by the ALDH1A1-TGF-β1 signaling mechanism

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Expression of a CD20-specific chimeric antigen receptor enhances cytotoxic activity of NK cells and overcomes NK-resistance of lymphoma and leukemia cells

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CAR-mediated targeting of NK cells overcomes tumor immune escape caused by ICAM-1 downregulation

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EV-3, an endogenous human erythropoietin isoform with distinct functional relevance

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Serum immune checkpoint profiling identifies soluble CD40 as a biomarker for pancreatic cancer

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442-Q CAR-mediated targeting of NK cells overcomes tumor immune escape caused by ICAM-1 downregulation

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Chemical Chaperones Improve Protein Secretion and Rescue Mutant Factor VIII in Mice with Hemophilia A

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Quality of life and metabolic outcomes after total pancreatectomy and simultaneous islet autotransplantation

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Hybrid Immunity Protects against Antibody Fading after SARS-CoV-2mRNA Vaccination in Kidney Transplant Recipients, Dialysis Patients, and Medical Personnel: 9 Months Data from the Prospective, Observa...

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