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Metabolic rewiring of macrophages by CpG potentiates clearance of cancer cells and overcomes tumor-expressed CD47−mediated ‘don’t-eat-me’ signal
Author / Creator:Liu, Mingen ; O’Connor, Roddy S. ; Trefely, Sophie ; Graham, Kathleen ; Snyder, Nathaniel W. ; Beatty, Gregory L.
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2019-03, Vol.20 (3), p.265-275
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Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate
Author / Creator:Zhao, Steven ; Jang, Cholsoon ; Liu, Joyce ; Uehara, Kahealani ; Gilbert, Michael ; Izzo, Luke ; Zeng, Xianfeng ; Trefely, Sophie ; Fernandez, Sully ; Carrer, Alessandro ; Miller, Katelyn D. ; Schug, Zachary T. ; Snyder, Nathaniel W. ; Gade, Terence P. ; Titchenell, Paul M. ; Rabinowitz, Joshua D. ; Wellen, Kathryn E.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2020-03, Vol.579 (7800), p.586-591
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FluxFix: automatic isotopologue normalization for metabolic tracer analysis
Author / Creator:Trefely, Sophie ; Ashwell, Peter ; Snyder, Nathaniel W.
Publisher:England: BioMed Central Ltd
Journal title:BMC bioinformatics, 2016-11, Vol.17 (1), p.485, Article 485
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Metabolite regulates differentiation
Author / Creator:Trefely, Sophie ; Wellen, Kathryn E.
Publisher:United States: The American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2018-05, Vol.360 (6389), p.603-604
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Glutamine deprivation triggers NAGK-dependent hexosamine salvage
Author / Creator:Campbell, Sydney ; Mesaros, Clementina ; Izzo, Luke ; Affronti, Hayley ; Noji, Michael ; Schaffer, Bethany E ; Tsang, Tiffany ; Sun, Kathryn ; Trefely, Sophie ; Kruijning, Salisa ; Blenis, John ; Blair, Ian A ; Wellen, Kathryn E
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2021-11, Vol.10
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Regulation of nuclear epigenome by mitochondrial DNA heteroplasmy
Author / Creator:Kopinski, Piotr K. ; Janssen, Kevin A. ; Schaefer, Patrick M. ; Trefely, Sophie ; Perry, Caroline E. ; Potluri, Prasanth ; Tintos-Hernandez, Jesus A. ; Singh, Larry N. ; Karch, Kelly R. ; Campbell, Sydney L. ; Doan, Mary T. ; Jiang, Helen ; Nissim, Itzhak ; Nakamaru-Ogiso, Eiko ; Wellen, Kathryn E. ; Snyder, Nathaniel W. ; Garcia, Benjamin A. ; Wallace, Douglas C.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2019-08, Vol.116 (32), p.16028-16035
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The CPT1a inhibitor, etomoxir induces severe oxidative stress at commonly used concentrations
Author / Creator:O’Connor, Roddy S. ; Guo, Lili ; Ghassemi, Saba ; Snyder, Nathaniel W. ; Worth, Andrew J. ; Weng, Liwei ; Kam, Yoonseok ; Philipson, Benjamin ; Trefely, Sophie ; Nunez-Cruz, Selene ; Blair, Ian A. ; June, Carl H. ; Milone, Michael C.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2018-04, Vol.8 (1), p.6289-9, Article 6289
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O-GlcNAc transferase regulates glioblastoma acetate metabolism via regulation of CDK5-dependent ACSS2 phosphorylation
Author / Creator:Lorela, Ciraku ; Bacigalupa, Zachary A ; Ju, Jing ; Moeller, Rebecca A ; Giang, Le Minh ; Lee, Rusia H ; Smith, Michael D ; Ferrer, Christina M ; Trefely Sophie ; Izzo, Luke T ; Doan, Mary T ; Gocal, Wiktoria A ; D’Agostino Luca ; Shi Wenyin ; Jackson, Joshua G ; Katsetos, Christos D ; Wellen, Kathryn E ; Snyder, Nathaniel W ; Reginato, Mauricio J
Publisher:New York: Nature Publishing Group
Journal title:Oncogene, 2022-04, Vol.41 (14), p.2122-2136
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CAR T-Cells Depend on the Coupling of NADH Oxidation with ATP Production
Author / Creator:Garcia-Canaveras, Juan ; Heo, David ; Trefely, Sophie ; Leferovich, John ; Xu, Chong ; Philipson, Benjamin ; Ghassemi, Saba ; Milone, Michael ; Moon, Edmund ; Snyder, Nathaniel ; June, Carl ; Rabinowitz, Joshua ; O’Connor, Roddy
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2021-09, Vol.10 (9), p.2334
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Dynamic protein deacetylation is a limited carbon source for acetyl-CoA-dependent metabolism
Author / Creator:Soaita, Ioana ; Megill, Emily ; Kantner, Daniel ; Chatoff, Adam ; Arany, Zoltan ; Snyder, Nathaniel W ; Wellen, Kathryn E ; Trefely, Sophie W
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2022-12
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The deacylase SIRT5 supports melanoma viability by influencing chromatin dynamics
Author / Creator:Giblin, William ; Bringman-Rodenbarger, Lauren ; Guo, Angela H. ; Kumar, Surinder ; Monovich, Alexander C. ; Mostafa, Ahmed M. ; Skinner, Mary E. ; Azar, Michelle ; Mady, Ahmed S.A. ; Chung, Carolina H. ; Kadambi, Namrata ; Melong, Keith-Allen ; Lee, Ho-Joon ; Zhang, Li ; Sajjakulnukit, Peter ; Trefely, Sophie ; Varner, Erika L. ; Iyer, Sowmya ; Wang, Min ; Wilmott, James S. ; Soyer, H. Peter ; Sturm, Richard A. ; Pritchard, Antonia L. ; Andea, Aleodor A. ; Scolyer, Richard A. ; Stark, Mitchell S. ; Scott, David A. ; Fullen, Douglas R. ; Bosenberg, Marcus W. ; Chandrasekaran, Sriram ; Nikolovska-Coleska, Zaneta ; Verhaegen, Monique E. ; Snyder, Nathaniel W. ; Rivera, Miguel N. ; Osterman, Andrei L. ; Lyssiotis, Costas A. ; Lombard, David B.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2021-06, Vol.131 (12), p.1-18
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LC-quadrupole/Orbitrap high-resolution mass spectrometry enables stable isotope-resolved simultaneous quantification and super(13)C-isotopic labeling of acyl-coenzyme A thioesters
Author / Creator:Frey, Alexander J ; Feldman, Daniel R ; Trefely, Sophie ; Worth, Andrew J ; Basu, Sankha S ; Snyder, Nathaniel W
Journal title:Analytical and bioanalytical chemistry, 2016-05, Vol.408 (13), p.3651-3658
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LC-quadrupole/Orbitrap high-resolution mass spectrometry enables stable isotope-resolved simultaneous quantification and ^sup 13^C-isotopic labeling of acyl-coenzyme A thioesters
Author / Creator:Frey, Alexander J ; Feldman, Daniel R ; Trefely, Sophie ; Worth, Andrew J ; Basu, Sankha S ; Snyder, Nathaniel W
Publisher:Heidelberg: Springer Nature B.V
Journal title:Analytical and bioanalytical chemistry, 2016-05, Vol.408 (13), p.3651
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LC-quadrupole/Orbitrap high-resolution mass spectrometry enables stable isotope-resolved simultaneous quantification and .sup.13C-isotopic labeling of acyl-coenzyme A thioesters
Author / Creator:Frey, Alexander J ; Feldman, Daniel R ; Trefely, Sophie ; Worth, Andrew J ; Basu, Sankha S ; Snyder, Nathaniel W
Publisher:Springer
Journal title:Analytical and bioanalytical chemistry, 2016-05, Vol.408 (13), p.3651
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P165 INFLUENCE OF THE GUT MICROBIOTA ON COLONIC HISTONE MODIFICATIONS THROUGH BUTYRATE METABOLISM UNDER HEALTHY AND INFLAMMATORY CONDITIONS
Author / Creator:Lund, Peder ; Smith, Sarah ; Simithy, Johayra ; Chau, Lillian ; Friedman, Elliot ; Saiman, Yedidya ; Gates, Leah ; Leboeuf, Marylene ; Trefely, Sophie ; Lopes, Mariana ; Yuan, Zuo-Fei ; Janssen, Kevin ; Kim, Min-Soo ; Petucci, Christopher ; Snyder, Nathaniel ; Bewtra, Meena ; Allis, C David ; Wu, Gary ; Garcia, Benjamin
Publisher:US: Oxford University Press
Journal title:Inflammatory bowel diseases, 2020-01, Vol.26 (Supplement_1), p.S40-S41
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Disrupted propionate metabolism evokes transcriptional changes in the heart by increasing histone acetylation and propionylation
Author / Creator:Park, Kyung Chan ; Crump, Nicholas T. ; Louwman, Niamh ; Krywawych, Steve ; Cheong, Yuen Jian ; Vendrell, Iolanda ; Gill, Eleanor K. ; Gunadasa-Rohling, Mala ; Ford, Kerrie L. ; Hauton, David ; Fournier, Marjorie ; Pires, Elisabete ; Watson, Lydia ; Roseman, Gerald ; Holder, James ; Koschinski, Andreas ; Carnicer, Ricardo ; Curtis, M. Kate ; Zaccolo, Manuela ; Hulikova, Alzbeta ; Fischer, Roman ; Kramer, Holger B. ; McCullagh, James S. O. ; Trefely, Sophie ; Milne, Thomas A. ; Swietach, Pawel
Publisher:England: Nature Publishing Group
Journal title:Nature Cardiovascular Research, 2023-12, Vol.2 (12), p.1221-1245
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LC-quadrupole/Orbitrap high-resolution mass spectrometry enables stable isotope-resolved simultaneous quantification and 13C-isotopic labeling of acyl-coenzyme A thioesters
Author / Creator:Frey, Alexander J. ; Feldman, Daniel R. ; Trefely, Sophie ; Worth, Andrew J. ; Basu, Sankha S. ; Snyder, Nathaniel W.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Analytical and bioanalytical chemistry, 2016-05, Vol.408 (13), p.3651-3658
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The carnitine shuttle links mitochondrial metabolism to histone acetylation and lipogenesis
Author / Creator:Izzo, Luke ; Trefely, Sophie ; Demetriadou, Christina ; Drummond, Jack ; Mizukami, Takuya ; Kuprasertkul, Nina ; Farria, Aimee ; Nguyen, Phuong ; Reich, Lauren ; Shaffer, Joshua ; Affronti, Hayley ; Carrer, Alessandro ; Andrews, Andrew ; Capell, Brian C. ; Snyder, Nathaniel W. ; Wellen, Kathryn E.
Publisher:Cold Spring Harbor Laboratory
Journal title:bioRxiv, 2022-09
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Quantification of lactoyl-CoA by liquid chromatography mass spectrometry in mammalian cells and tissues
Author / Creator:Varner, Erika L ; Trefely, Sophie ; Bartee, David ; von Krusenstiern, Eliana ; Izzo, Luke ; Bekeova, Carmen ; O’Connor, Roddy S ; Seifert, Erin L. ; Wellen, Kathryn ; Meier, Jordan L. ; Snyder, Nathaniel W.
Publisher:Cold Spring Harbor Laboratory
Journal title:bioRxiv, 2020-06
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Quantitative prospective and retrospective mass spectrometry of lactoyl-CoA in mammalian cells and tissues
Author / Creator:Varner, Erika L ; Trefely, Sophie ; Bartee, David ; Eliana Von Krusenstiern ; Izzo, Luke ; Bekeova, Carmen ; O'connor, Roddy S ; Seifert, Erin L ; Wellen, Kathryn ; Meier, Jordan L ; Snyder, Nathaniel W
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2020-03
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Showing 1 to 20 of 28 results

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Metabolic rewiring of macrophages by CpG potentiates clearance of cancer cells and overcomes tumor-expressed CD47−mediated ‘don’t-eat-me’ signal

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Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate

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FluxFix: automatic isotopologue normalization for metabolic tracer analysis

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Metabolite regulates differentiation

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Glutamine deprivation triggers NAGK-dependent hexosamine salvage

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Regulation of nuclear epigenome by mitochondrial DNA heteroplasmy

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The CPT1a inhibitor, etomoxir induces severe oxidative stress at commonly used concentrations

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O-GlcNAc transferase regulates glioblastoma acetate metabolism via regulation of CDK5-dependent ACSS2 phosphorylation

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CAR T-Cells Depend on the Coupling of NADH Oxidation with ATP Production

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Dynamic protein deacetylation is a limited carbon source for acetyl-CoA-dependent metabolism

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The deacylase SIRT5 supports melanoma viability by influencing chromatin dynamics

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LC-quadrupole/Orbitrap high-resolution mass spectrometry enables stable isotope-resolved simultaneous quantification and super(13)C-isotopic labeling of acyl-coenzyme A thioesters

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LC-quadrupole/Orbitrap high-resolution mass spectrometry enables stable isotope-resolved simultaneous quantification and ^sup 13^C-isotopic labeling of acyl-coenzyme A thioesters

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LC-quadrupole/Orbitrap high-resolution mass spectrometry enables stable isotope-resolved simultaneous quantification and .sup.13C-isotopic labeling of acyl-coenzyme A thioesters

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P165 INFLUENCE OF THE GUT MICROBIOTA ON COLONIC HISTONE MODIFICATIONS THROUGH BUTYRATE METABOLISM UNDER HEALTHY AND INFLAMMATORY CONDITIONS

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Disrupted propionate metabolism evokes transcriptional changes in the heart by increasing histone acetylation and propionylation

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LC-quadrupole/Orbitrap high-resolution mass spectrometry enables stable isotope-resolved simultaneous quantification and 13C-isotopic labeling of acyl-coenzyme A thioesters

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The carnitine shuttle links mitochondrial metabolism to histone acetylation and lipogenesis

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Quantification of lactoyl-CoA by liquid chromatography mass spectrometry in mammalian cells and tissues

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Quantitative prospective and retrospective mass spectrometry of lactoyl-CoA in mammalian cells and tissues

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