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ArticlesPeer ReviewedFull Text
Interleukin-18 in Health and Disease
Author / Creator:Yasuda, Koubun ; Nakanishi, Kenji ; Tsutsui, Hiroko
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2019-02, Vol.20 (3), p.649
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Importance of Kupffer cells in the development of acute liver injuries in mice
Author / Creator:Tsutsui, Hiroko ; Nishiguchi, Shuhei
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2014-05, Vol.15 (5), p.7711-7730
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Anti-interleukin-6 receptor antibody treatment ameliorates postoperative adhesion formation
Author / Creator:Uyama, Naoki ; Tsutsui, Hiroko ; Wu, Songtao ; Yasuda, Koubun ; Hatano, Etsuro ; Qin, Xian-Yang ; Kojima, Soichi ; Fujimoto, Jiro
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-11, Vol.9 (1), p.17558-14, Article 17558
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Contribution of IL-33–activated type II innate lymphoid cells to pulmonary eosinophilia in intestinal nematode-infected mice
Author / Creator:Yasuda, Koubun ; Muto, Taichiro ; Kawagoe, Tatsukata ; Matsumoto, Makoto ; Sasaki, Yuki ; Matsushita, Kazufumi ; Taki, Yuko ; Futatsugi-Yumikura, Shizue ; Tsutsui, Hiroko ; Ishii, Ken J ; Yoshimoto, Tomohiro ; Akira, Shizuo ; Nakanishi, Kenji
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2012-02, Vol.109 (9), p.3451-3456
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Extracellular ATP mediates mast cell-dependent intestinal inflammation through P2X7 purinoceptors
Author / Creator:Kurashima, Yosuke ; Amiya, Takeaki ; Nochi, Tomonori ; Fujisawa, Kumiko ; Haraguchi, Takeshi ; Iba, Hideo ; Tsutsui, Hiroko ; Sato, Shintaro ; Nakajima, Sachiko ; Iijima, Hideki ; Kubo, Masato ; Kunisawa, Jun ; Kiyono, Hiroshi
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2012-09, Vol.3 (1), p.1034-1034, Article 1034
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Pu-erh tea extract ameliorates high-fat diet-induced nonalcoholic steatohepatitis and insulin resistance by modulating hepatic IL-6/STAT3 signaling in mice
Author / Creator:Cai, Xianbin ; Fang, Chongye ; Hayashi, Shuhei ; Hao, Shumei ; Zhao, Mingming ; Tsutsui, Hiroko ; Nishiguchi, Shuhei ; Sheng, Jun
Publisher:Tokyo: Springer Japan
Journal title:Journal of gastroenterology, 2016-08, Vol.51 (8), p.819-829
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ArticlesPeer ReviewedFull Text
Interleukin-1 Family Cytokines in Liver Diseases
Author / Creator:Tsutsui, Hiroko ; Cai, Xianbin ; Hayashi, Shuhei
Publisher:Cairo, Egypt: Hindawi Limiteds
Journal title:Mediators of Inflammation, 2015-01, Vol.2015 (2015), p.328-346-333
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Caffeine protects against stress-induced murine depression through activation of PPARγC1α-mediated restoration of the kynurenine pathway in the skeletal muscle
Author / Creator:Fang, Chongye ; Hayashi, Shuhei ; Du, Xiaocui ; Cai, Xianbin ; Deng, Bin ; Zheng, Hongmei ; Ishido, Satoshi ; Tsutsui, Hiroko ; Sheng, Jun
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-03, Vol.11 (1), p.7287-13, Article 7287
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Shigella IpaH7.8 E3 ubiquitin ligase targets glomulin and activates inflammasomes to demolish macrophages
Author / Creator:Suzuki, Shiho ; Mimuro, Hitomi ; Kim, Minsoo ; Ogawa, Michinaga ; Ashida, Hiroshi ; Toyotome, Takahito ; Franchi, Luigi ; Suzuki, Masato ; Sanada, Takahito ; Suzuki, Toshihiko ; Tsutsui, Hiroko ; Núñez, Gabriel ; Sasakawa, Chihiro
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2014-10, Vol.111 (40), p.E4254-E4263
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ArticlesPeer ReviewedFull Text
INTERLEUKIN-18 REGULATES BOTH TH1 AND TH2 RESPONSES
Author / Creator:Nakanishi, Kenji ; Yoshimoto, Tomohiro ; Tsutsui, Hiroko ; Okamura, Haruki
Publisher:Palo Alto, CA 94303-0139: Annual Reviews
Journal title:Annual review of immunology, 2001-01, Vol.19 (1), p.423-474
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Caspases as the Key Effectors of Inflammatory Responses Against Bacterial Infection
Author / Creator:Uchiyama, Ryosuke ; Tsutsui, Hiroko
Publisher:Basel: Springer Basel
Journal title:Archivum Immunologiae et Therapiae Experimentalis, 2015-02, Vol.63 (1), p.1-13
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ASC and NLRP3 maintain innate immune homeostasis in the airway through an inflammasome-independent mechanism
Author / Creator:Fang, Rendong ; Uchiyama, Ryosuke ; Sakai, Shunsuke ; Hara, Hideki ; Tsutsui, Hiroko ; Suda, Takashi ; Mitsuyama, Masao ; Kawamura, Ikuo ; Tsuchiya, Kohsuke
Publisher:New York: Nature Publishing Group US
Journal title:Mucosal immunology, 2019-09, Vol.12 (5), p.1092-1103
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ArticlesPeer ReviewedFull Text
Pu’erh tea extract-mediated protection against hepatosteatosis and insulin resistance in mice with diet-induced obesity is associated with the induction of de novo lipogenesis in visceral adipose tiss...
Author / Creator:Cai, Xianbin ; Hayashi, Shuhei ; Fang, Chongye ; Hao, Shumei ; Wang, Xuanjun ; Nishiguchi, Shuhei ; Tsutsui, Hiroko ; Sheng, Jun
Publisher:Tokyo: Springer Japan
Journal title:Journal of gastroenterology, 2017-12, Vol.52 (12), p.1240-1251
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ArticlesPeer ReviewedFull Text
Targeting solid tumors with non‐pathogenic obligate anaerobic bacteria
Author / Creator:Taniguchi, Shun’ichiro ; Fujimori, Minoru ; Sasaki, Takayuki ; Tsutsui, Hiroko ; Shimatani, Yuko ; Seki, Keiichi ; Amano, Jun
Publisher:Oxford, UK: Blackwell Publishing Ltd
Journal title:Cancer science, 2010-09, Vol.101 (9), p.1925-1932
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Effect of Helicobacter pylori infection on the link between GLP-1 expression and motility of the gastrointestinal tract
Author / Creator:Eda, Hirotsugu ; Fukui, Hirokazu ; Uchiyama, Ryosuke ; Kitayama, Yoshitaka ; Hara, Ken ; Yang, Mo ; Kodani, Mio ; Tomita, Toshihiko ; Oshima, Tadayuki ; Watari, Jiro ; Tsutsui, Hiroko ; Miwa, Hiroto
Publisher:United States: Public Library of Science
Journal title:PloS one, 2017-05, Vol.12 (5), p.e0177232-e0177232
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ArticlesPeer ReviewedFull Text
Contribution of IL-18 to Atopic-Dermatitis-Like Skin Inflammation Induced by Staphylococcus aureus Product in Mice
Author / Creator:Terada, Makoto ; Tsutsui, Hiroko ; Imai, Yasutomo ; Yasuda, Koubun ; Mizutani, Hitoshi ; Yamanishi, Kiyofumi ; Kubo, Masato ; Matsui, Kiyoshi ; Sano, Hajime ; Nakanishi, Kenji
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2006-06, Vol.103 (23), p.8816-8821
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ArticlesPeer ReviewedFull Text
The TLR4/TRIF-Mediated Activation of NLRP3 Inflammasome Underlies Endotoxin-Induced Liver Injury in Mice
Author / Creator:Tsutsui, Hiroko ; Imamura, Michiko ; Fujimoto, Jiro ; Nakanishi, Kenji
Publisher:Cairo, Egypt: Hindawi Puplishing Corporation
Journal title:Gastroenterology research and practice, 2010-01, Vol.2010 (2010), p.1-11
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IL-18, Although Antiallergic When Administered with IL-12, Stimulates IL-4 and Histamine Release by Basophils
Author / Creator:Yoshimoto, Tomohiro ; Tsutsui, Hiroko ; Tominaga, Kouji ; Hoshino, Katsuaki ; Okamura, Haruki ; Akira, Shizuo ; Paul, William E. ; Nakanishi, Kenji
Publisher:United States: National Academy of Sciences of the United States of America
Journal title:Proceedings of the National Academy of Sciences - PNAS, 1999-11, Vol.96 (24), p.13962-13966
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IL-18 Contributes to the Spontaneous Development of Atopic Dermatitis-like Inflammatory Skin Lesion Independently of IgE/Stat6 under Specific Pathogen-Free Conditions
Author / Creator:Konishi, Hiroshi ; Tsutsui, Hiroko ; Murakami, Takaaki ; Yumikura-Futatsugi, Shizue ; Yamanaka, Kei-ichi ; Tanaka, Minoru ; Iwakura, Yohichiro ; Suzuki, Noboru ; Takeda, Kiyoshi ; Akira, Shizuo ; Nakanishi, Kenji ; Mizutani, Hitoshi
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2002-08, Vol.99 (17), p.11340-11345
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Immunotherapeutic applications of IL-18
Author / Creator:Tsutsui, Hiroko ; Nakanishi, Kenji
Publisher:London: Future Medicine Ltd
Journal title:Immunotherapy, 2012-12, Vol.4 (12), p.1883-1894
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Interleukin-18 in Health and Disease

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Importance of Kupffer cells in the development of acute liver injuries in mice

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Anti-interleukin-6 receptor antibody treatment ameliorates postoperative adhesion formation

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Contribution of IL-33–activated type II innate lymphoid cells to pulmonary eosinophilia in intestinal nematode-infected mice

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Extracellular ATP mediates mast cell-dependent intestinal inflammation through P2X7 purinoceptors

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Pu-erh tea extract ameliorates high-fat diet-induced nonalcoholic steatohepatitis and insulin resistance by modulating hepatic IL-6/STAT3 signaling in mice

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Interleukin-1 Family Cytokines in Liver Diseases

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Caffeine protects against stress-induced murine depression through activation of PPARγC1α-mediated restoration of the kynurenine pathway in the skeletal muscle

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Shigella IpaH7.8 E3 ubiquitin ligase targets glomulin and activates inflammasomes to demolish macrophages

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INTERLEUKIN-18 REGULATES BOTH TH1 AND TH2 RESPONSES

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Caspases as the Key Effectors of Inflammatory Responses Against Bacterial Infection

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ASC and NLRP3 maintain innate immune homeostasis in the airway through an inflammasome-independent mechanism

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Pu’erh tea extract-mediated protection against hepatosteatosis and insulin resistance in mice with diet-induced obesity is associated with the induction of de novo lipogenesis in visceral adipose tiss...

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Targeting solid tumors with non‐pathogenic obligate anaerobic bacteria

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Effect of Helicobacter pylori infection on the link between GLP-1 expression and motility of the gastrointestinal tract

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Contribution of IL-18 to Atopic-Dermatitis-Like Skin Inflammation Induced by Staphylococcus aureus Product in Mice

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The TLR4/TRIF-Mediated Activation of NLRP3 Inflammasome Underlies Endotoxin-Induced Liver Injury in Mice

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IL-18, Although Antiallergic When Administered with IL-12, Stimulates IL-4 and Histamine Release by Basophils

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IL-18 Contributes to the Spontaneous Development of Atopic Dermatitis-like Inflammatory Skin Lesion Independently of IgE/Stat6 under Specific Pathogen-Free Conditions

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Immunotherapeutic applications of IL-18

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