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ArticlesPeer ReviewedFull Text
Comparison of machine-learning methodologies for accurate diagnosis of sepsis using microarray gene expression data
Author / Creator:Schaack, Dominik ; Weigand, Markus A. ; Uhle, Florian
Publisher:United States: Public Library of Science
Journal title:PloS one, 2021-05, Vol.16 (5), p.e0251800-e0251800
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Interleukin-3 amplifies acute inflammation and is a potential therapeutic target in sepsis
Author / Creator:Weber, Georg F. ; Chousterman, Benjamin G. ; He, Shun ; Fenn, Ashley M. ; Nairz, Manfred ; Anzai, Atsushi ; Brenner, Thorsten ; Uhle, Florian ; Iwamoto, Yoshiko ; Robbins, Clinton S. ; Noiret, Lorette ; Maier, Sarah L. ; Zönnchen, Tina ; Rahbari, Nuh N. ; Schölch, Sebastian ; Klotzsche-von Ameln, Anne ; Chavakis, Triantafyllos ; Weitz, Jürgen ; Hofer, Stefan ; Weigand, Markus A. ; Nahrendorf, Matthias ; Weissleder, Ralph ; Swirski, Filip K.
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2015-03, Vol.347 (6227), p.1260-1265
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Acute fibrinolysis shutdown occurs early in septic shock and is associated with increased morbidity and mortality: results of an observational pilot study
Author / Creator:Schmitt, Felix Carl Fabian ; Manolov, Vasil ; Morgenstern, Jakob ; Fleming, Thomas ; Heitmeier, Stefan ; Uhle, Florian ; Al-Saeedi, Mohammed ; Hackert, Thilo ; Bruckner, Thomas ; Schöchl, Herbert ; Weigand, Markus Alexander ; Hofer, Stefan ; Brenner, Thorsten
Publisher:Cham: Springer International Publishing
Journal title:Annals of intensive care, 2019-01, Vol.9 (1), p.19-15, Article 19
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The immunosuppressive face of sepsis early on intensive care unit—A large-scale microarray meta-analysis
Author / Creator:Schaack, Dominik ; Siegler, Benedikt Hermann ; Tamulyte, Sandra ; Weigand, Markus Alexander ; Uhle, Florian
Publisher:United States: Public Library of Science
Journal title:PloS one, 2018-06, Vol.13 (6), p.e0198555-e0198555
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Preoperative neutrophil to lymphocyte ratio and platelet to lymphocyte ratio are associated with major adverse cardiovascular and cerebrovascular events in coronary heart disease patients undergoing n...
Author / Creator:Larmann, Jan ; Handke, Jessica ; Scholz, Anna S. ; Dehne, Sarah ; Arens, Christoph ; Gillmann, Hans-Jörg ; Uhle, Florian ; Motsch, Johann ; Weigand, Markus A. ; Janssen, Henrike
Publisher:England: BioMed Central Ltd
Journal title:BMC cardiovascular disorders, 2020-05, Vol.20 (1), p.230-230, Article 230
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Sevoflurane depletes macrophages from the melanoma microenvironment
Author / Creator:Sztwiertnia, Isabella ; Schenz, Judith ; Bomans, Katharina ; Schaack, Dominik ; Ohnesorge, Johanna ; Tamulyte, Sandra ; Weigand, Markus A. ; Uhle, Florian
Publisher:United States: Public Library of Science
Journal title:PloS one, 2020-05, Vol.15 (5), p.e0233789-e0233789
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Delta-like canonical Notch ligand 1 is predictive for sepsis and acute kidney injury in surgical intensive care patients
Author / Creator:Schneck, Emmanuel ; Edinger, Fabian ; Uhle, Florian ; Markmann, Melanie ; Hecker, Andreas ; Weigand, Markus A. ; Sander, Michael ; Koch, Christian
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2022-08, Vol.12 (1), p.13355-13355, Article 13355
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Gut microbiome patterns correlate with higher postoperative complication rates after pancreatic surgery
Author / Creator:Schmitt, Felix C. F. ; Brenner, Thorsten ; Uhle, Florian ; Loesch, Svenja ; Hackert, Thilo ; Ulrich, Alexis ; Hofer, Stefan ; Dalpke, Alexander H. ; Weigand, Markus A. ; Boutin, Sébastien
Publisher:England: BioMed Central Ltd
Journal title:BMC microbiology, 2019-02, Vol.19 (1), p.42-42, Article 42
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A blood-based miRNA signature with prognostic value for overall survival in advanced stage non-small cell lung cancer treated with immunotherapy
Author / Creator:Rajakumar, Timothy ; Horos, Rastislav ; Jehn, Julia ; Schenz, Judith ; Muley, Thomas ; Pelea, Oana ; Hofmann, Sarah ; Kittner, Paul ; Kahraman, Mustafa ; Heuvelman, Marco ; Sikosek, Tobias ; Feufel, Jennifer ; Skottke, Jasmin ; Nötzel, Dennis ; Hinkfoth, Franziska ; Tikk, Kaja ; Daniel-Moreno, Alberto ; Ceiler, Jessika ; Mercaldo, Nathaniel ; Uhle, Florian ; Uhle, Sandra ; Weigand, Markus A. ; Elshiaty, Mariam ; Lusky, Fabienne ; Schindler, Hannah ; Ferry, Quentin ; Sauka-Spengler, Tatjana ; Wu, Qianxin ; Rabe, Klaus F. ; Reck, Martin ; Thomas, Michael ; Christopoulos, Petros ; Steinkraus, Bruno R.
Publisher:London: Nature Publishing Group UK
Journal title:NPJ precision oncology, 2022-03, Vol.6 (1), p.19-19, Article 19
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Postoperative abdominal sepsis induces selective and persistent changes in CTCF binding within the MHC-II region of human monocytes
Author / Creator:Siegler, Benedikt Hermann ; Altvater, Marc ; Thon, Jan Niklas ; Neuhaus, Christopher ; Arens, Christoph ; Uhle, Florian ; Lichtenstern, Christoph ; Weigand, Markus Alexander ; Weiterer, Sebastian
Publisher:United States: Public Library of Science
Journal title:PloS one, 2021-05, Vol.16 (5), p.e0250818-e0250818
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Impact of human sepsis on CCCTC-binding factor associated monocyte transcriptional response of Major Histocompatibility Complex II components
Author / Creator:Siegler, Benedikt Hermann ; Uhle, Florian ; Lichtenstern, Christoph ; Arens, Christoph ; Bartkuhn, Marek ; Weigand, Markus Alexander ; Weiterer, Sebastian
Publisher:United States: Public Library of Science
Journal title:PloS one, 2018-09, Vol.13 (9), p.e0204168-e0204168
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Effect of moderate elevated intra-abdominal pressure on lung mechanics and histological lung injury at different positive end-expiratory pressures
Author / Creator:Fiedler, Mascha O. ; Deutsch, B. Luise ; Simeliunas, Emilis ; Diktanaite, Dovile ; Harms, Alexander ; Brune, Maik ; Uhle, Florian ; Weigand, Markus ; Brenner, Thorsten ; Kalenka, Armin
Publisher:United States: Public Library of Science
Journal title:PloS one, 2020-04, Vol.15 (4), p.e0230830
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Paternal sepsis induces alterations of the sperm methylome and dampens offspring immune responses—an animal study
Author / Creator:Bomans, Katharina ; Schenz, Judith ; Tamulyte, Sandra ; Schaack, Dominik ; Weigand, Markus Alexander ; Uhle, Florian
Publisher:Germany: BioMed Central Ltd
Journal title:Clinical epigenetics, 2018-06, Vol.10 (1), p.89-89, Article 89
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Sepsis Induces Specific Changes in Histone Modification Patterns in Human Monocytes
Author / Creator:Weiterer, Sebastian ; Uhle, Florian ; Lichtenstern, Christoph ; Siegler, Benedikt H. ; Bhuju, Sabin ; Jarek, Michael ; Bartkuhn, Marek ; Weigand, Markus A.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-03, Vol.10 (3), p.e0121748-e0121748
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The Glyoxalase System and Methylglyoxal-Derived Carbonyl Stress in Sepsis: Glycotoxic Aspects of Sepsis Pathophysiology
Author / Creator:Schmoch, Thomas ; Uhle, Florian ; Siegler, Benedikt H. ; Fleming, Thomas ; Morgenstern, Jakob ; Nawroth, Peter P. ; Weigand, Markus A. ; Brenner, Thorsten
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2017-03, Vol.18 (3), p.657-657
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Advanced glycation endproducts induce self- and cross-tolerance in monocytes
Author / Creator:Uhle, Florian ; Weiterer, Sebastian ; Siegler, Benedikt Hermann ; Brenner, Thorsten ; Lichtenstern, Christoph ; Weigand, Markus Alexander
Publisher:Cham: Springer International Publishing
Journal title:Inflammation research, 2017-11, Vol.66 (11), p.961-968
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Bedside hyperspectral imaging for the evaluation of microcirculatory alterations in perioperative intensive care medicine: a study protocol for an observational clinical pilot study (HySpI-ICU)
Author / Creator:Dietrich, Maximilian ; Marx, Sebastian ; Bruckner, Thomas ; Nickel, Felix ; Müller-Stich, Beat Peter ; Hackert, Thilo ; Weigand, Markus A ; Uhle, Florian ; Brenner, Thorsten ; Schmidt, Karsten
Publisher:England: British Medical Journal Publishing Group
Journal title:BMJ open, 2020-09, Vol.10 (9), p.e035742-e035742
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miR-Blood – a small RNA atlas of human blood components
Author / Creator:Jehn, Julia ; Trudzinski, Franziska ; Horos, Rastislav ; Schenz, Judith ; Uhle, Florian ; Weigand, Markus A. ; Frank, Maurice ; Kahraman, Mustafa ; Heuvelman, Marco ; Sikosek, Tobias ; Rajakumar, Timothy ; Gerwing, Jennifer ; Skottke, Jasmin ; Daniel-Moreno, Alberto ; Rudolf, Christina ; Hinkfoth, Franziska ; Tikk, Kaja ; Christopoulos, Petros ; Klotz, Laura V. ; Winter, Hauke ; Kreuter, Michael ; Steinkraus, Bruno R.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific data, 2024-02, Vol.11 (1), p.164-164, Article 164
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Soluble Intercellular Adhesion Molecule- (sICAM-) 1, Thrombospondin-1, and Vinculin for the Identification of Septic Shock Patients Suffering from an Invasive Fungal Infection
Author / Creator:Brenner, Thorsten ; Weigand, Markus Alexander ; Zimmermann, Stefan ; Heininger, Alexandra ; Bruckner, Thomas ; Uhle, Florian ; Sigl, Annette ; Incamps, Anne ; Decker, Sebastian O. ; Hirtz, Christophe
Publisher:Cairo, Egypt: Hindawi Publishing Corporation
Journal title:Mediators of inflammation, 2020, Vol.2020 (2020), p.1-13
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Concurrent Change in Serum Cholinesterase Activity and Midregional-Proadrennomedullin Level Could Predict Patient Outcome following Liver Transplantation
Author / Creator:Decker, Sebastian O. ; Krüger, Albert ; Wilk, Henryk ; Uhle, Florian ; Bruckner, Thomas ; Hofer, Stefan ; Weigand, Markus A. ; Brenner, Thorsten ; Zivkovic, Aleksandar R.
Publisher:Basel: MDPI AG
Journal title:Biomolecules (Basel, Switzerland), 2022-07, Vol.12 (7), p.989
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Comparison of machine-learning methodologies for accurate diagnosis of sepsis using microarray gene expression data

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Interleukin-3 amplifies acute inflammation and is a potential therapeutic target in sepsis

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Acute fibrinolysis shutdown occurs early in septic shock and is associated with increased morbidity and mortality: results of an observational pilot study

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The immunosuppressive face of sepsis early on intensive care unit—A large-scale microarray meta-analysis

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Preoperative neutrophil to lymphocyte ratio and platelet to lymphocyte ratio are associated with major adverse cardiovascular and cerebrovascular events in coronary heart disease patients undergoing n...

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Sevoflurane depletes macrophages from the melanoma microenvironment

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Delta-like canonical Notch ligand 1 is predictive for sepsis and acute kidney injury in surgical intensive care patients

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Gut microbiome patterns correlate with higher postoperative complication rates after pancreatic surgery

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A blood-based miRNA signature with prognostic value for overall survival in advanced stage non-small cell lung cancer treated with immunotherapy

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Postoperative abdominal sepsis induces selective and persistent changes in CTCF binding within the MHC-II region of human monocytes

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Impact of human sepsis on CCCTC-binding factor associated monocyte transcriptional response of Major Histocompatibility Complex II components

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Effect of moderate elevated intra-abdominal pressure on lung mechanics and histological lung injury at different positive end-expiratory pressures

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Paternal sepsis induces alterations of the sperm methylome and dampens offspring immune responses—an animal study

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Sepsis Induces Specific Changes in Histone Modification Patterns in Human Monocytes

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The Glyoxalase System and Methylglyoxal-Derived Carbonyl Stress in Sepsis: Glycotoxic Aspects of Sepsis Pathophysiology

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Advanced glycation endproducts induce self- and cross-tolerance in monocytes

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Bedside hyperspectral imaging for the evaluation of microcirculatory alterations in perioperative intensive care medicine: a study protocol for an observational clinical pilot study (HySpI-ICU)

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miR-Blood – a small RNA atlas of human blood components

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Soluble Intercellular Adhesion Molecule- (sICAM-) 1, Thrombospondin-1, and Vinculin for the Identification of Septic Shock Patients Suffering from an Invasive Fungal Infection

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Concurrent Change in Serum Cholinesterase Activity and Midregional-Proadrennomedullin Level Could Predict Patient Outcome following Liver Transplantation

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