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ArticlesPeer ReviewedFull Text
Autophagy in Chronically Ischemic Myocardium
Author / Creator:Yan, Lin ; Vatner, Dorothy E. ; Kim, Song-Jung ; Ge, Hui ; Masurekar, Malthi ; Massover, William H. ; Yang, Guiping ; Matsui, Yutaka ; Sadoshima, Junichi ; Vatner, Stephen F. ; Braunwald, Eugene
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2005-09, Vol.102 (39), p.13807-13812
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Inhibition of Adenylyl Cyclase Type 5 Increases Longevity and Healthful Aging through Oxidative Stress Protection
Author / Creator:Vatner, Stephen F. ; Vatner, Dorothy E. ; Pachon, Ronald E.
Publisher:Cairo, Egypt: Hindawi Publishing Corporation
Journal title:Oxidative medicine and cellular longevity, 2015-01, Vol.2015 (2015), p.1-13
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Activation of Mst1 causes dilated cardiomyopathy by stimulating apoptosis without compensatory ventricular myocyte hypertrophy
Author / Creator:Yamamoto, Shimako ; Yang, Guiping ; Zablocki, Daniela ; Liu, Jing ; Hong, Chull ; Kim, Song-Jung ; Soler, Sandra ; Odashima, Mari ; Thaisz, Jill ; Yehia, Ghassan ; Molina, Carlos A. ; Yatani, Atsuko ; Vatner, Dorothy E. ; Vatner, Stephen F. ; Sadoshima, Junichi
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2003-05, Vol.111 (10), p.1463-1474
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Disruption of Type 5 Adenylyl Cyclase Gene Preserves Cardiac Function against Pressure Overload
Author / Creator:Okumura, Satoshi ; Takagi, Gen ; Kawabe, Jun-ichi ; Yang, Guiping ; Lee, Ming-Chih ; Hong, Chull ; Liu, Jing ; Vatner, Dorothy E. ; Sadoshima, Junichi ; Vatner, Stephen F. ; Ishikawa, Yoshihiro
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2003-08, Vol.100 (17), p.9986-9990
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The Regulator of G Protein Signaling 14 Knockout Mouse, a Model of Healthful Longevity Protects Against Obesity and Glucose Intolerance Through a Brown Adipose Tissue Mechanism
Author / Creator:Vatner, Stephen F. ; Zhang, Jie ; Oydanich, Marko ; Vatner, Dorothy E.
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2025-04, Vol.26 (9), p.4113
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Secreted frizzled-related protein 2, a novel mechanism to induce myocardial ischemic protection through angiogenesis
Author / Creator:Vatner, Dorothy E. ; Oydanich, Marko ; Zhang, Jie ; Babici, Denis ; Vatner, Stephen F.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Basic research in cardiology, 2020-07, Vol.115 (4), p.48-48, Article 48
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ArticlesPeer ReviewedFull Text
Smooth Muscle Myosin Inhibition: A Novel Therapeutic Approach for Pulmonary Hypertension
Author / Creator:Ho, David ; Chen, Li ; Zhao, Xin ; Durham, Nicquanna ; Pannirselvam, Malar ; Vatner, Dorothy E. ; Morgans, David J. ; Malik, Fady I. ; Vatner, Stephen F. ; Shen, You-Tang
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-05, Vol.7 (5), p.e36302
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Enhanced longevity and metabolism by brown adipose tissue with disruption of the regulator of G protein signaling 14
Author / Creator:Vatner, Dorothy E. ; Zhang, Jie ; Oydanich, Marko ; Guers, John ; Katsyuba, Elena ; Yan, Lin ; Sinclair, David ; Auwerx, Johan ; Vatner, Stephen F.
Publisher:England: John Wiley & Sons, Inc
Journal title:Aging cell, 2018-08, Vol.17 (4), p.e12751-n/a
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Disruption of adenylyl cyclase type 5 mimics exercise training
Author / Creator:Guers, John J. ; Zhang, Jie ; Campbell, Sara C. ; Oydanich, Marko ; Vatner, Dorothy E. ; Vatner, Stephen F.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Basic research in cardiology, 2017-11, Vol.112 (6), p.59-12, Article 59
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Mst1 inhibition rescues β1-adrenergic cardiomyopathy by reducing myocyte necrosis and non-myocyte apoptosis rather than myocyte apoptosis
Author / Creator:Lee, Grace J. ; Yan, Lin ; Vatner, Dorothy E. ; Vatner, Stephen F.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Basic research in cardiology, 2015-03, Vol.110 (2), p.7-7, Article 7
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Minority investigators lack NIH funding
Author / Creator:Guers, John J. ; Gwathmey, Judith ; Haddad, Georges ; Vatner, Dorothy E. ; Vatner, Stephen F.
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2017-06, Vol.356 (6342), p.1018-1019
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ArticlesPeer ReviewedFull Text
Myocardial ischemic protection in natural mammalian hibernation
Author / Creator:Yan, Lin ; Kudej, Raymond K. ; Vatner, Dorothy E. ; Vatner, Stephen F.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Basic research in cardiology, 2015-03, Vol.110 (2), p.9-9, Article 9
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Modulation of β-adrenergic receptor signaling in heart failure and longevity: targeting adenylyl cyclase type 5
Author / Creator:Ho, David ; Yan, Lin ; Iwatsubo, Kousaku ; Vatner, Dorothy E. ; Vatner, Stephen F.
Publisher:Boston: Springer US
Journal title:Heart failure reviews, 2010-09, Vol.15 (5), p.495-512
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Calorie restriction can reverse, as well as prevent, aging cardiomyopathy
Author / Creator:Yan, Lin ; Gao, Shumin ; Ho, David ; Park, Misun ; Ge, Hui ; Wang, Chunbo ; Tian, Yimin ; Lai, Lo ; De Lorenzo, Mariana S ; Vatner, Dorothy E ; Vatner, Stephen F
Publisher:Dordrecht: Springer Nature B.V
Journal title:GeroScience, 2013-12, Vol.35 (6), p.2177
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Type 5 adenylyl cyclase disruption leads to enhanced exercise performance
Author / Creator:Vatner, Dorothy E. ; Yan, Lin ; Lai, Lo ; Yuan, Chujun ; Mouchiroud, Laurent ; Pachon, Ronald E. ; Zhang, Jie ; Dillinger, Jean‐Guillaume ; Houtkooper, Riekelt H. ; Auwerx, Johan ; Vatner, Stephen F.
Publisher:England: John Wiley & Sons, Inc
Journal title:Aging cell, 2015-12, Vol.14 (6), p.1075-1084
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The MEKK1-JNK pathway plays a protective role in pressure overload but does not mediate cardiac hypertrophy
Author / Creator:Sadoshima, Junichi ; Montagne, Olivier ; Wang, Qian ; Yang, Guiping ; Warden, Jill ; Liu, Jing ; Takagi, Gen ; Karoor, Vijaya ; Hong, Chull ; Johnson, Gary L. ; Vatner, Dorothy E. ; Vatner, Stephen F.
Publisher:United States
Journal title:The Journal of clinical investigation, 2002-07, Vol.110 (2), p.271-279
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Reduced malignancy as a mechanism for longevity in mice with adenylyl cyclase type 5 disruption
Author / Creator:De Lorenzo, Mariana S. ; Chen, Wen ; Baljinnyam, Erdene ; Carlini, María J. ; La Perle, Krista ; Bishop, Sanford P. ; Wagner, Thomas E. ; Rabson, Arnold B. ; Vatner, Dorothy E. ; Puricelli, Lydia I. ; Vatner, Stephen F.
Publisher:England: John Wiley & Sons, Inc
Journal title:Aging cell, 2014-02, Vol.13 (1), p.102-110
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Novel mechanisms for caspase inhibition protecting cardiac function with chronic pressure overload
Author / Creator:Park, Misun ; Vatner, Stephen F. ; Yan, Lin ; Gao, Shumin ; Yoon, Seunghun ; Lee, Grace Jung Ah ; Xie, Lai-Hua ; Kitsis, Richard N. ; Vatner, Dorothy E.
Publisher:Berlin/Heidelberg: Springer-Verlag
Journal title:Basic research in cardiology, 2013-01, Vol.108 (1), p.324-324, Article 324
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Gene Program for Cardiac Cell Survival Induced by Transient Ischemia in Conscious Pigs
Author / Creator:Depre, Christophe ; Tomlinson, James E. ; Kudej, Raymond K. ; Gaussin, Vinciane ; Thompson, Erika ; Kim, Song-Jung ; Vatner, Dorothy E. ; Topper, James N. ; Vatner, Stephen F.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2001-07, Vol.98 (16), p.9336-9341
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ReviewsPeer ReviewedFull Text
Myocardial apoptosis in heart disease: does the emperor have clothes?
Author / Creator:Corbalan, J. Jose ; Vatner, Dorothy E. ; Vatner, Stephen F.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Basic research in cardiology, 2016, Vol.111 (3), p.31-31, Article 31
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Showing 1 to 20 of 32 results

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Autophagy in Chronically Ischemic Myocardium

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Inhibition of Adenylyl Cyclase Type 5 Increases Longevity and Healthful Aging through Oxidative Stress Protection

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Activation of Mst1 causes dilated cardiomyopathy by stimulating apoptosis without compensatory ventricular myocyte hypertrophy

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Disruption of Type 5 Adenylyl Cyclase Gene Preserves Cardiac Function against Pressure Overload

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The Regulator of G Protein Signaling 14 Knockout Mouse, a Model of Healthful Longevity Protects Against Obesity and Glucose Intolerance Through a Brown Adipose Tissue Mechanism

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Secreted frizzled-related protein 2, a novel mechanism to induce myocardial ischemic protection through angiogenesis

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Smooth Muscle Myosin Inhibition: A Novel Therapeutic Approach for Pulmonary Hypertension

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Enhanced longevity and metabolism by brown adipose tissue with disruption of the regulator of G protein signaling 14

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Disruption of adenylyl cyclase type 5 mimics exercise training

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Mst1 inhibition rescues β1-adrenergic cardiomyopathy by reducing myocyte necrosis and non-myocyte apoptosis rather than myocyte apoptosis

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Minority investigators lack NIH funding

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Myocardial ischemic protection in natural mammalian hibernation

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Modulation of β-adrenergic receptor signaling in heart failure and longevity: targeting adenylyl cyclase type 5

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Calorie restriction can reverse, as well as prevent, aging cardiomyopathy

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Type 5 adenylyl cyclase disruption leads to enhanced exercise performance

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The MEKK1-JNK pathway plays a protective role in pressure overload but does not mediate cardiac hypertrophy

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Reduced malignancy as a mechanism for longevity in mice with adenylyl cyclase type 5 disruption

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Novel mechanisms for caspase inhibition protecting cardiac function with chronic pressure overload

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Gene Program for Cardiac Cell Survival Induced by Transient Ischemia in Conscious Pigs

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Myocardial apoptosis in heart disease: does the emperor have clothes?

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