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15 results for Verona,+Guglielmo

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ArticlesPeer ReviewedFull Text
Plasmin activity promotes amyloid deposition in a transgenic model of human transthyretin amyloidosis
Author / Creator:Slamova, Ivana ; Adib, Rozita ; Ellmerich, Stephan ; Golos, Michal R. ; Gilbertson, Janet A. ; Botcher, Nicola ; Canetti, Diana ; Taylor, Graham W. ; Rendell, Nigel ; Tennent, Glenys A. ; Verona, Guglielmo ; Porcari, Riccardo ; Mangione, P. Patrizia ; Gillmore, Julian D. ; Pepys, Mark B. ; Bellotti, Vittorio ; Hawkins, Philip N. ; Al-Shawi, Raya ; Simons, J. Paul
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-12, Vol.12 (1), p.7112-7112, Article 7112
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L444P Gba1 mutation increases formation and spread of α-synuclein deposits in mice injected with mouse α-synuclein pre-formed fibrils
Author / Creator:Migdalska‐Richards, Anna ; Wegrzynowicz, Michal ; Harrison, Ian F. ; Verona, Guglielmo ; Bellotti, Vittorio ; Spillantini, Maria Grazia ; Schapira, Anthony H. V.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2020-08, Vol.15 (8), p.e0238075-e0238075
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Targeted Extracellular Vesicle Gene Therapy for Modulating Alpha-Synuclein Expression in Gut and Spinal Cord
Author / Creator:Izco, Maria ; Schleef, Martin ; Schmeer, Marco ; Carlos, Estefania ; Verona, Guglielmo ; Alvarez-Erviti, Lydia
Publisher:Switzerland: MDPI AG
Journal title:Pharmaceutics, 2023-04, Vol.15 (4), p.1230
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A novel mechano‐enzymatic cleavage mechanism underlies transthyretin amyloidogenesis
Author / Creator:Marcoux, Julien ; Mangione, P Patrizia ; Porcari, Riccardo ; Degiacomi, Matteo T ; Verona, Guglielmo ; Taylor, Graham W ; Giorgetti, Sofia ; Raimondi, Sara ; Sanglier‐Cianférani, Sarah ; Benesch, Justin LP ; Cecconi, Ciro ; Naqvi, Mohsin M ; Gillmore, Julian D ; Hawkins, Philip N ; Stoppini, Monica ; Robinson, Carol V ; Pepys, Mark B ; Bellotti, Vittorio
Publisher:London: Nature Publishing Group UK
Journal title:EMBO molecular medicine, 2015-10, Vol.7 (10), p.1337-1349
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D25V apolipoprotein C-III variant causes dominant hereditary systemic amyloidosis and confers cardiovascular protective lipoprotein profile
Author / Creator:Valleix, Sophie ; Verona, Guglielmo ; Jourde-Chiche, Noémie ; Nédelec, Brigitte ; Mangione, P. Patrizia ; Bridoux, Frank ; Mangé, Alain ; Dogan, Ahmet ; Goujon, Jean-Michel ; Lhomme, Marie ; Dauteuille, Carolane ; Chabert, Michèle ; Porcari, Riccardo ; Waudby, Christopher A. ; Relini, Annalisa ; Talmud, Philippa J. ; Kovrov, Oleg ; Olivecrona, Gunilla ; Stoppini, Monica ; Christodoulou, John ; Hawkins, Philip N. ; Grateau, Gilles ; Delpech, Marc ; Kontush, Anatol ; Gillmore, Julian D. ; Kalopissis, Athina D. ; Bellotti, Vittorio
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2016-01, Vol.7 (1), p.10353-10353, Article 10353
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Inhibition of the mechano-enzymatic amyloidogenesis of transthyretin: role of ligand affinity, binding cooperativity and occupancy of the inner channel
Author / Creator:Verona, Guglielmo ; Mangione, P. Patrizia ; Raimondi, Sara ; Giorgetti, Sofia ; Faravelli, Giulia ; Porcari, Riccardo ; Corazza, Alessandra ; Gillmore, Julian D. ; Hawkins, Philip N. ; Pepys, Mark B. ; Taylor, Graham W. ; Bellotti, Vittorio
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-03, Vol.7 (1), p.182-7, Article 182
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Calcium Binds to Transthyretin with Low Affinity
Author / Creator:Cantarutti, Cristina ; Mimmi, Maria Chiara ; Verona, Guglielmo ; Mandaliti, Walter ; Taylor, Graham W. ; Mangione, P. Patrizia ; Giorgetti, Sofia ; Bellotti, Vittorio ; Corazza, Alessandra
Publisher:Basel: MDPI AG
Journal title:Biomolecules (Basel, Switzerland), 2022-08, Vol.12 (8), p.1066
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Human wild-type and D76N β2-microglobulin variants are significant proteotoxic and metabolic stressors for transgenic C. elegans
Author / Creator:Raimondi, Sara ; Faravelli, Giulia ; Nocerino, Paola ; Mondani, Valentina ; Baruffaldi, Alma ; Marchese, Loredana ; Mimmi, Maria Chiara ; Canetti, Diana ; Verona, Guglielmo ; Caterino, Marianna ; Ruoppolo, Margherita ; Mangione, P Patrizia ; Bellotti, Vittorio ; Lavatelli, Francesca ; Giorgetti, Sofia
Publisher:Bethesda: John Wiley & Sons, Inc
Journal title:FASEB bioAdvances, 2023-11, Vol.5 (11), p.484-505
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A specific nanobody prevents amyloidogenesis of D76N β2-microglobulin in vitro and modifies its tissue distribution in vivo
Author / Creator:Raimondi, Sara ; Porcari, Riccardo ; Mangione, P. Patrizia ; Verona, Guglielmo ; Marcoux, Julien ; Giorgetti, Sofia ; Taylor, Graham W. ; Ellmerich, Stephan ; Ballico, Maurizio ; Zanini, Stefano ; Pardon, Els ; Al-Shawi, Raya ; Simons, J. Paul ; Corazza, Alessandra ; Fogolari, Federico ; Leri, Manuela ; Stefani, Massimo ; Bucciantini, Monica ; Gillmore, Julian D. ; Hawkins, Philip N. ; Valli, Maurizia ; Stoppini, Monica ; Robinson, Carol V. ; Steyaert, Jan ; Esposito, Gennaro ; Bellotti, Vittorio
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-04, Vol.7 (1), Article 46711
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Antibody-Associated Reversal of ATTR Amyloidosis–Related Cardiomyopathy
Author / Creator:Fontana, Marianna ; Gilbertson, Janet ; Verona, Guglielmo ; Riefolo, Mattia ; Slamova, Ivana ; Leone, Ornella ; Rowczenio, Dorota ; Botcher, Nicola ; Ioannou, Adam ; Patel, Rishi K. ; Razvi, Yousuf ; Martinez-Naharro, Ana ; Whelan, Carol J. ; Venneri, Lucia ; Duhlin, Amanda ; Canetti, Diana ; Ellmerich, Stephan ; Moon, James C. ; Kellman, Peter ; Al-Shawi, Raya ; McCoy, Laura ; Simons, J. Paul ; Hawkins, Philip N. ; Gillmore, Julian D.
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2023-06, Vol.388 (23), p.2199-2201
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L444P Gba1 mutation increases formation and spread of [alpha]-synuclein deposits in mice injected with mouse [alpha]-synuclein pre-formed fibrils
Author / Creator:Migdalska-Richards, Anna ; Wegrzynowicz, Michal ; Harrison, Ian F ; Verona, Guglielmo ; Bellotti, Vittorio ; Spillantini, Maria Grazia ; Schapira, Anthony H.V
Publisher:Public Library of Science
Journal title:PloS one, 2020-08, Vol.15 (8), p.e0238075
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Human wild‐type and D76N β 2 ‐microglobulin variants are significant proteotoxic and metabolic stressors for transgenic C. elegans
Author / Creator:Raimondi, Sara ; Faravelli, Giulia ; Nocerino, Paola ; Mondani, Valentina ; Baruffaldi, Alma ; Marchese, Loredana ; Mimmi, Maria Chiara ; Canetti, Diana ; Verona, Guglielmo ; Caterino, Marianna ; Ruoppolo, Margherita ; Mangione, P. Patrizia ; Bellotti, Vittorio ; Lavatelli, Francesca ; Giorgetti, Sofia
Publisher:United States
Journal title:FASEB bioAdvances, 2023-11, Vol.5 (11), p.484-505
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A specific nanobody prevents amyloidogenesis of D76N β 2 -microglobulin in vitro and modifies its tissue distribution in vivo
Author / Creator:Raimondi, Sara ; Porcari, Riccardo ; Mangione, P Patrizia ; Verona, Guglielmo ; Marcoux, Julien ; Giorgetti, Sofia ; Taylor, Graham W ; Ellmerich, Stephan ; Ballico, Maurizio ; Zanini, Stefano ; Pardon, Els ; Al-Shawi, Raya ; Simons, J Paul ; Corazza, Alessandra ; Fogolari, Federico ; Leri, Manuela ; Stefani, Massimo ; Bucciantini, Monica ; Gillmore, Julian D ; Hawkins, Philip N ; Valli, Maurizia ; Stoppini, Monica ; Robinson, Carol V ; Steyaert, Jan ; Esposito, Gennaro ; Bellotti, Vittorio
Publisher:England
Journal title:Scientific reports, 2017-04, Vol.7, p.46711
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ArticlesPeer ReviewedFull Text
A specific nanobody prevents amyloidogenesis of D76N [beta]2-microglobulin in vitro and modifies its tissue distribution in vivo
Author / Creator:Raimondi, Sara ; Porcari, Riccardo ; Mangione, P Patrizia ; Verona, Guglielmo ; Marcoux, Julien ; Giorgetti, Sofia ; Taylor, Graham W ; Ellmerich, Stephan ; Ballico, Maurizio ; Zanini, Stefano ; Pardon, Els ; Al-shawi, Raya ; Simons, J Paul ; Corazza, Alessandra ; Fogolari, Federico ; Leri, Manuela ; Stefani, Massimo ; Bucciantini, Monica ; Gillmore, Julian D ; Hawkins, Philip N ; Valli, Maurizia ; Stoppini, Monica ; Robinson, Carol V ; Steyaert, Jan ; Esposito, Gennaro ; Bellotti, Vittorio
Publisher:London: Nature Publishing Group
Journal title:Scientific reports, 2017-04, Vol.7, p.46711
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Amyloid damage to islet β-cells in type 2 diabetes: hypoxia or pseudo-hypoxia?
Author / Creator:Bellotti, Vittorio ; Corazza, Alessandra ; Foglia, Beatrice ; Novo, Erica ; Simons, J Paul ; Mangione, P Patrizia ; Verona, Guglielmo ; Canetti, Diana ; Nocerino, Paola ; Obici, Laura ; Vanoli, Alessandro ; Paulli, Marco ; Giorgetti, Sofia ; Raimondi, Sara ; Al-Shawi, Raya ; Tennent, Glenys A ; Taylor, Graham W ; Gillmore, Julian D ; Pepys, Mark B ; Parola, Maurizio
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2019-10
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Plasmin activity promotes amyloid deposition in a transgenic model of human transthyretin amyloidosis

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L444P Gba1 mutation increases formation and spread of α-synuclein deposits in mice injected with mouse α-synuclein pre-formed fibrils

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Targeted Extracellular Vesicle Gene Therapy for Modulating Alpha-Synuclein Expression in Gut and Spinal Cord

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A novel mechano‐enzymatic cleavage mechanism underlies transthyretin amyloidogenesis

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D25V apolipoprotein C-III variant causes dominant hereditary systemic amyloidosis and confers cardiovascular protective lipoprotein profile

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Inhibition of the mechano-enzymatic amyloidogenesis of transthyretin: role of ligand affinity, binding cooperativity and occupancy of the inner channel

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Calcium Binds to Transthyretin with Low Affinity

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Human wild-type and D76N β2-microglobulin variants are significant proteotoxic and metabolic stressors for transgenic C. elegans

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A specific nanobody prevents amyloidogenesis of D76N β2-microglobulin in vitro and modifies its tissue distribution in vivo

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Antibody-Associated Reversal of ATTR Amyloidosis–Related Cardiomyopathy

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L444P Gba1 mutation increases formation and spread of [alpha]-synuclein deposits in mice injected with mouse [alpha]-synuclein pre-formed fibrils

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Human wild‐type and D76N β 2 ‐microglobulin variants are significant proteotoxic and metabolic stressors for transgenic C. elegans

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A specific nanobody prevents amyloidogenesis of D76N β 2 -microglobulin in vitro and modifies its tissue distribution in vivo

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A specific nanobody prevents amyloidogenesis of D76N [beta]2-microglobulin in vitro and modifies its tissue distribution in vivo

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Amyloid damage to islet β-cells in type 2 diabetes: hypoxia or pseudo-hypoxia?

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