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Precipitation in and Supersaturation of Contents of the Upper Small Intestine After Administration of Two Weak Bases to Fasted Adults
Author / Creator:Psachoulias, Dimitrios ; Vertzoni, Maria ; Goumas, Konstantinos ; Kalioras, Vasilios ; Beato, Stefania ; Butler, James ; Reppas, Christos
Publisher:Boston: Springer US
Journal title:Pharmaceutical research, 2011-12, Vol.28 (12), p.3145-3158
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Measuring pH and Buffer Capacity in Fluids Aspirated from the Fasted Upper Gastrointestinal Tract of Healthy Adults
Author / Creator:Litou, Chara ; Psachoulias, Dimitrios ; Vertzoni, Maria ; Dressman, Jennifer ; Reppas, Christos
Publisher:New York: Springer US
Journal title:Pharmaceutical research, 2020-03, Vol.37 (3), p.42-42, Article 42
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Characteristics of the Human Upper Gastrointestinal Contents in the Fasted State Under Hypo- and A-chlorhydric Gastric Conditions Under Conditions of Typical Drug – Drug Interaction Studies
Author / Creator:Litou, Chara ; Vertzoni, Maria ; Goumas, Constantinos ; Vasdekis, Vassilis ; Xu, Wei ; Kesisoglou, Filippos ; Reppas, Christos
Publisher:New York: Springer US
Journal title:Pharmaceutical research, 2016-06, Vol.33 (6), p.1399-1412
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An In Vitro Methodology for Forecasting Luminal Concentrations and Precipitation of Highly Permeable Lipophilic Weak Bases in the Fasted Upper Small Intestine
Author / Creator:Psachoulias, Dimitrios ; Vertzoni, Maria ; Butler, James ; Busby, David ; Symillides, Moira ; Dressman, Jennifer ; Reppas, Christos
Publisher:Boston: Springer US
Journal title:Pharmaceutical research, 2012-12, Vol.29 (12), p.3486-3498
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The effect of propranolol on gastrointestinal motility and permeability in patients with cirrhosis and significant portal hypertension
Author / Creator:Xirouchakis, Elias ; Kranidioti, Hariklia ; Hadziyanni, Emilia ; Kourikou, Anastasia ; Reppas, Christos ; Vertzoni, Maria ; Papadopoulos, Nikolaos ; Deutsch, Melanie ; Papatheodoridis, George ; Manolakopoulos, Spilios
Publisher:England: BioMed Central Ltd
Journal title:BMC gastroenterology, 2024-11, Vol.24 (1), p.420-11, Article 420
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The Use of Population Pharmacokinetics to Extrapolate Food Effects from Human Adults and Beagle Dogs to the Pediatric Population Illustrated with Paracetamol as a Test Case
Author / Creator:Gasthuys, Elke ; Sandra, Louis ; Statelova, Marina ; Vertzoni, Maria ; Vermeulen, An
Publisher:Switzerland: MDPI AG
Journal title:Pharmaceuticals (Basel, Switzerland), 2023-12, Vol.17 (1), p.53
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On the Design of Food Effect Studies in Adults for Extrapolating Oral Drug Absorption Data to Infants: an Exploratory Study Highlighting the Importance of Infant Food
Author / Creator:Statelova, Marina ; Goumas, Konstantinos ; Fotaki, Nikoletta ; Holm, René ; Symillides, Mira ; Reppas, Christos ; Vertzoni, Maria
Publisher:Cham: Springer International Publishing
Journal title:The AAPS journal, 2019-12, Vol.22 (1), p.6-6, Article 6
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Characterization of the Contents of Ascending Colon to Which Drugs are Exposed After Oral Administration to Healthy Adults
Author / Creator:Diakidou, Amalia ; Vertzoni, Maria ; Goumas, Konstantinos ; Söderlind, Erik ; Abrahamsson, Bertil ; Dressman, Jennifer ; Reppas, Christos
Publisher:Boston: Boston : Springer US
Journal title:Pharmaceutical research, 2009-09, Vol.26 (9), p.2141-2151
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Understanding the Impact of Age-Related Changes in Pediatric GI Solubility by Multivariate Data Analysis
Author / Creator:Guimarães, Mariana ; Maharaj, Anil ; Edginton, Andrea ; Vertzoni, Maria ; Fotaki, Nikoletta
Publisher:Switzerland: MDPI AG
Journal title:Pharmaceutics, 2022-02, Vol.14 (2), p.356
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Challenges in Permeability Assessment for Oral Drug Product Development
Author / Creator:Koziolek, Mirko ; Augustijns, Patrick ; Berger, Constantin ; Cristofoletti, Rodrigo ; Dahlgren, David ; Keemink, Janneke ; Matsson, Pär ; McCartney, Fiona ; Metzger, Marco ; Mezler, Mario ; Niessen, Janis ; Polli, James E. ; Vertzoni, Maria ; Weitschies, Werner ; Dressman, Jennifer
Publisher:Basel: MDPI AG
Journal title:Pharmaceutics, 2023-09, Vol.15 (10), p.2397
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Simulation of Intraluminal Performance of Lipophilic Weak Bases in Fasted Healthy Adults Using DDDPlus.sup.TM
Author / Creator:Statelova, Marina ; Vertzoni, Maria ; Kourentas, Alexandros
Publisher:Springer
Journal title:The AAPS journal, 2022-09, Vol.24 (5)
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Simulation of Intraluminal Performance of Lipophilic Weak Bases in Fasted Healthy Adults Using DDDPlusTM
Author / Creator:Statelova, Marina ; Vertzoni, Maria ; Kourentas, Alexandros
Publisher:Cham: Springer International Publishing
Journal title:The AAPS journal, 2022-08, Vol.24 (5), Article 89
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Characterization of Contents of Distal Ileum and Cecum to Which Drugs/Drug Products are Exposed During Bioavailability/Bioequivalence Studies in Healthy Adults
Author / Creator:Reppas, Christos ; Karatza, Eleni ; Goumas, Constantinos ; Markopoulos, Constantinos ; Vertzoni, Maria
Publisher:New York: Springer US
Journal title:Pharmaceutical research, 2015-10, Vol.32 (10), p.3338-3349
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Performance Evaluation of Montelukast Pediatric Formulations: Part II — a PBPK Modelling Approach
Author / Creator:Guimarães, Mariana ; Vertzoni, Maria ; Fotaki, Nikoletta
Publisher:Cham: Springer International Publishing
Journal title:The AAPS journal, 2022-01, Vol.24 (1), p.27-27, Article 27
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Performance Evaluation of Montelukast Pediatric Formulations: Part I—Age-Related In Vitro Conditions
Author / Creator:Guimarães, Mariana ; Somville, Pascal ; Vertzoni, Maria ; Fotaki, Nikoletta
Publisher:Cham: Springer International Publishing
Journal title:The AAPS journal, 2022-01, Vol.24 (1), p.26-26, Article 26
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Evaluating pediatric and adult simulated fluids solubility: Abraham solvation parameters and multivariate analysis
Author / Creator:Guimarães, Mariana ; Kuentz, Martin ; Vertzoni, Maria ; Fotaki, Nikoletta
Publisher:New York: Springer US
Journal title:Pharmaceutical research, 2021-11, Vol.38 (11), p.1889-1896
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Successful Extrapolation of Paracetamol Exposure from Adults to Infants After Oral Administration of a Pediatric Aqueous Suspension Is Highly Dependent on the Study Dosing Conditions
Author / Creator:Statelova, Marina ; Holm, René ; Fotaki, Nikoletta ; Reppas, Christos ; Vertzoni, Maria
Publisher:Cham: Springer International Publishing
Journal title:The AAPS journal, 2020-09, Vol.22 (6), p.126-126, Article 126
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ArticlesPeer ReviewedFull Text
Simulation of Intraluminal Performance of Lipophilic Weak Bases in Fasted Healthy Adults Using DDDPlus TM
Author / Creator:Statelova, Marina ; Vertzoni, Maria ; Kourentas, Alexandros
Publisher:United States
Journal title:The AAPS journal, 2022-08, Vol.24 (5), p.89
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Factors Affecting Successful Extrapolation of Ibuprofen Exposure from Adults to Pediatric Populations After Oral Administration of a Pediatric Aqueous Suspension
Author / Creator:Statelova, Marina ; Holm, René ; Fotaki, Nikoletta ; Reppas, Christos ; Vertzoni, Maria
Publisher:Cham: Springer International Publishing
Journal title:The AAPS journal, 2020-11, Vol.22 (6), p.146-146, Article 146
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Supersaturated lipid-based drug delivery systems - exploring impact of lipid composition type and drug properties on supersaturability and physical stability
Author / Creator:Ilie, Alexandra-Roxana ; Griffin, Brendan T. ; Kolakovic, Ruzica ; Vertzoni, Maria ; Kuentz, Martin ; Holm, René
Publisher:England: Taylor & Francis
Journal title:Drug development and industrial pharmacy, 2020-03, Vol.46 (3), p.356-364
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Showing 1 to 20 of 27 results

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Precipitation in and Supersaturation of Contents of the Upper Small Intestine After Administration of Two Weak Bases to Fasted Adults

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Measuring pH and Buffer Capacity in Fluids Aspirated from the Fasted Upper Gastrointestinal Tract of Healthy Adults

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Characteristics of the Human Upper Gastrointestinal Contents in the Fasted State Under Hypo- and A-chlorhydric Gastric Conditions Under Conditions of Typical Drug – Drug Interaction Studies

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An In Vitro Methodology for Forecasting Luminal Concentrations and Precipitation of Highly Permeable Lipophilic Weak Bases in the Fasted Upper Small Intestine

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The effect of propranolol on gastrointestinal motility and permeability in patients with cirrhosis and significant portal hypertension

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The Use of Population Pharmacokinetics to Extrapolate Food Effects from Human Adults and Beagle Dogs to the Pediatric Population Illustrated with Paracetamol as a Test Case

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On the Design of Food Effect Studies in Adults for Extrapolating Oral Drug Absorption Data to Infants: an Exploratory Study Highlighting the Importance of Infant Food

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Characterization of the Contents of Ascending Colon to Which Drugs are Exposed After Oral Administration to Healthy Adults

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Understanding the Impact of Age-Related Changes in Pediatric GI Solubility by Multivariate Data Analysis

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Challenges in Permeability Assessment for Oral Drug Product Development

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Simulation of Intraluminal Performance of Lipophilic Weak Bases in Fasted Healthy Adults Using DDDPlus.sup.TM

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Simulation of Intraluminal Performance of Lipophilic Weak Bases in Fasted Healthy Adults Using DDDPlusTM

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Characterization of Contents of Distal Ileum and Cecum to Which Drugs/Drug Products are Exposed During Bioavailability/Bioequivalence Studies in Healthy Adults

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Performance Evaluation of Montelukast Pediatric Formulations: Part II — a PBPK Modelling Approach

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Performance Evaluation of Montelukast Pediatric Formulations: Part I—Age-Related In Vitro Conditions

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Evaluating pediatric and adult simulated fluids solubility: Abraham solvation parameters and multivariate analysis

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Successful Extrapolation of Paracetamol Exposure from Adults to Infants After Oral Administration of a Pediatric Aqueous Suspension Is Highly Dependent on the Study Dosing Conditions

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Simulation of Intraluminal Performance of Lipophilic Weak Bases in Fasted Healthy Adults Using DDDPlus TM

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Factors Affecting Successful Extrapolation of Ibuprofen Exposure from Adults to Pediatric Populations After Oral Administration of a Pediatric Aqueous Suspension

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Supersaturated lipid-based drug delivery systems - exploring impact of lipid composition type and drug properties on supersaturability and physical stability

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