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ArticlesPeer ReviewedFull Text
Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer
Author / Creator:Salvati, Annamaria ; Melone, Viola ; Sellitto, Assunta ; Rizzo, Francesca ; Tarallo, Roberta ; Nyman, Tuula A. ; Giurato, Giorgio ; Nassa, Giovanni ; Weisz, Alessandro
Publisher:London: BioMed Central Ltd
Journal title:Breast cancer research : BCR, 2022-07, Vol.24 (1), p.1-52, Article 52
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TNF-alpha and metalloproteases as key players in melanoma cells aggressiveness
Author / Creator:Rossi, Stefania ; Cordella, Martina ; Tabolacci, Claudio ; Nassa, Giovanni ; D’Arcangelo, Daniela ; Senatore, Cinzia ; Pagnotto, Paolo ; Magliozzi, Roberta ; Salvati, Annamaria ; Weisz, Alessandro ; Facchiano, Antonio ; Facchiano, Francesco
Publisher:England: BioMed Central Ltd
Journal title:Journal of experimental & clinical cancer research, 2018-12, Vol.37 (1), p.326-326, Article 326
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Specific gene expression signatures induced by the multiple oncogenic alterations that occur within the PTEN/PI3K/AKT pathway in lung cancer
Author / Creator:De Marco, Carmela ; Laudanna, Carmelo ; Rinaldo, Nicola ; Oliveira, Duarte Mendes ; Ravo, Maria ; Weisz, Alessandro ; Ceccarelli, Michele ; Caira, Elvira ; Rizzuto, Antonia ; Zoppoli, Pietro ; Malanga, Donatella ; Viglietto, Giuseppe
Publisher:United States: Public Library of Science
Journal title:PloS one, 2017-06, Vol.12 (6), p.e0178865-e0178865
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BRPF1 inhibition reduces migration and invasion of metastatic ovarian cancer cells, representing a potential therapeutic target
Author / Creator:Alexandrova, Elena ; Smal, Marharyta ; Di Rosa, Domenico ; Brancaccio, Rosario Nicola ; Parisi, Roberto ; Russo, Fabio ; Tarallo, Roberta ; Nassa, Giovanni ; Giurato, Giorgio ; Weisz, Alessandro ; Rizzo, Francesca
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2025-03, Vol.15 (1), p.7602-15, Article 7602
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The nuclear receptor ERβ engages AGO2 in regulation of gene transcription, RNA splicing and RISC loading
Author / Creator:Tarallo, Roberta ; Giurato, Giorgio ; Bruno, Giuseppina ; Ravo, Maria ; Rizzo, Francesca ; Salvati, Annamaria ; Ricciardi, Luca ; Marchese, Giovanna ; Cordella, Angela ; Rocco, Teresa ; Gigantino, Valerio ; Pierri, Biancamaria ; Cimmino, Giovanni ; Milanesi, Luciano ; Ambrosino, Concetta ; Nyman, Tuula A. ; Nassa, Giovanni ; Weisz, Alessandro
Publisher:England: BioMed Central
Journal title:Genome Biology, 2017-10, Vol.18 (1), p.189-189, Article 189
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Enhanced ZNF521 expression induces an aggressive phenotype in human ovarian carcinoma cell lines
Author / Creator:Scicchitano, Stefania ; Montalcini, Ylenia ; Lucchino, Valeria ; Melocchi, Valentina ; Gigantino, Valerio ; Chiarella, Emanuela ; Bianchi, Fabrizio ; Weisz, Alessandro ; Mesuraca, Maria
Publisher:San Francisco: Public Library of Science
Journal title:PloS one, 2022-10, Vol.17 (10), p.e0274785-e0274785
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Does gut microbiota dysbiosis impact the metabolic alterations of hydrogen sulfide and lanthionine in patients with chronic kidney disease?
Author / Creator:Garcia-Martinez, Yuselys ; Alexandrova, Elena ; Iebba, Valerio ; Ferravante, Carlo ; Spinelli, Michelle ; Franci, Gianluigi ; Amoresano, Angela ; Weisz, Alessandro ; Trepiccione, Francesco ; Borriello, Margherita ; Ingrosso, Diego ; Perna, Alessandra F.
Publisher:England: BioMed Central Ltd
Journal title:BMC microbiology, 2024-10, Vol.24 (1), p.436-15, Article 436
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A ZFYVE19 gene mutation associated with neonatal cholestasis and cilia dysfunction: case report with a novel pathogenic variant
Author / Creator:Mandato, Claudia ; Siano, Maria Anna ; Nazzaro, Lucia ; Gelzo, Monica ; Francalanci, Paola ; Rizzo, Francesca ; D’Agostino, Ylenia ; Morleo, Manuela ; Brillante, Simona ; Weisz, Alessandro ; Franco, Brunella ; Vajro, Pietro
Publisher:England: BioMed Central Ltd
Journal title:Orphanet journal of rare diseases, 2021-04, Vol.16 (1), p.179-179, Article 179
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RIZ2 at the crossroad of the EGF/EGFR signaling in colorectal cancer
Author / Creator:Di Donato, Marzia ; Di Zazzo, Erika ; Salvati, Annamaria ; Sorrentino, Carmela ; Giurato, Giorgio ; Fiore, Donatella ; Proto, Maria Chiara ; Rienzo, Monica ; Casamassimi, Amelia ; Gazzerro, Patrizia ; Bifulco, Maurizio ; Castoria, Gabriella ; Weisz, Alessandro ; Nassa, Giovanni ; Abbondanza, Ciro
Publisher:London: BioMed Central Ltd
Journal title:Journal of translational medicine, 2023-10, Vol.21 (1), p.1-736, Article 736
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Essential gene screening identifies the bromodomain-containing protein BRPF1 as a new actionable target for endocrine therapy-resistant breast cancers
Author / Creator:Salvati, Annamaria ; Giurato, Giorgio ; Lamberti, Jessica ; Terenzi, Ilaria ; Crescenzo, Laura ; Melone, Viola ; Palo, Luigi ; Giordano, Alessandro ; Sabbatino, Francesco ; Roscigno, Giuseppina ; Quintavalle, Cristina ; Condorelli, Gerolama ; Rizzo, Francesca ; Tarallo, Roberta ; Nassa, Giovanni ; Weisz, Alessandro
Publisher:England: BioMed Central Ltd
Journal title:Molecular cancer, 2024-08, Vol.23 (1), p.160-11, Article 160
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LncRNA PVT1 links estrogen receptor alpha and the polycomb repressive complex 2 in suppression of pro-apoptotic genes in hormone-responsive breast cancer
Author / Creator:Melone, Viola ; Palumbo, Domenico ; Palo, Luigi ; Brusco, Noemi ; Salvati, Annamaria ; Tarallo, Antonietta ; Giurato, Giorgio ; Rizzo, Francesca ; Nassa, Giovanni ; Weisz, Alessandro ; Tarallo, Roberta
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2025-02, Vol.16 (1), p.80-13
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ArticlesPeer ReviewedFull Text
Signaling Networks Associated with AKT Activation in Non-Small Cell Lung Cancer (NSCLC): New Insights on the Role of Phosphatydil-Inositol-3 kinase
Author / Creator:Scrima, Marianna ; De Marco, Carmela ; Fabiani, Fernanda ; Franco, Renato ; Pirozzi, Giuseppe ; Rocco, Gaetano ; Ravo, Maria ; Weisz, Alessandro ; Zoppoli, Pietro ; Ceccarelli, Michele ; Botti, Gerardo ; Malanga, Donatella ; Viglietto, Giuseppe
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-02, Vol.7 (2), p.e30427
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HOME-BIO (sHOtgun MEtagenomic analysis of BIOlogical entities): a specific and comprehensive pipeline for metagenomic shotgun sequencing data analysis
Author / Creator:Ferravante, Carlo ; Memoli, Domenico ; Palumbo, Domenico ; Ciaramella, Paolo ; Di Loria, Antonio ; D’Agostino, Ylenia ; Nassa, Giovanni ; Rizzo, Francesca ; Tarallo, Roberta ; Weisz, Alessandro ; Giurato, Giorgio
Publisher:London: BioMed Central Ltd
Journal title:BMC bioinformatics, 2021-07, Vol.22 (S7), p.1-106, Article 106
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Circulating SARS-CoV-2 variants in Italy, October 2020–March 2021
Author / Creator:Lai, Alessia ; Bergna, Annalisa ; Menzo, Stefano ; Zehender, Gianguglielmo ; Caucci, Sara ; Ghisetti, Valeria ; Rizzo, Francesca ; Maggi, Fabrizio ; Cerutti, Francesco ; Giurato, Giorgio ; Weisz, Alessandro ; Turchi, Chiara ; Bruzzone, Bianca ; Ceccherini Silberstein, Francesca ; Clementi, Nicola ; Callegaro, Annapaola ; Sagradi, Fabio ; Francisci, Daniela ; Venanzi Rullo, Emmanuele ; Vicenti, Ilaria ; Clementi, Massimo ; Galli, Massimo ; Balotta, Claudia ; Gori, Maria ; Bagnarelli, Patrizia ; Baj, Andreina ; Novazzi, Federica ; Orsi, Andrea ; Caligiuri, Patrizia ; Boccotti, Simona ; Bellocchi, Maria Concetta ; Sarmati, Loredana ; Andreoni, Massimo ; Mancini, Nicasio ; Criscuolo, Elena ; Gallitelli, Rosa ; Testa, Sophie ; Dragoni, Filippo ; Zazzi, Maurizio
Publisher:London: BioMed Central Ltd
Journal title:Virology journal, 2021-08, Vol.18 (1), p.1-168, Article 168
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Combinatorial targeting of menin and the histone methyltransferase DOT1L as a novel therapeutic strategy for treatment of chemotherapy-resistant ovarian cancer
Author / Creator:Alexandrova, Elena ; Lamberti, Jessica ; Memoli, Domenico ; Quercia, Claudia ; Melone, Viola ; Rizzo, Francesca ; Tarallo, Roberta ; Giurato, Giorgio ; Nassa, Giovanni ; Weisz, Alessandro
Publisher:London: BioMed Central
Journal title:Cancer cell international, 2022-11, Vol.22 (1), p.1-336, Article 336
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Identification of functional pathways and molecular signatures in neuroendocrine neoplasms by multi-omics analysis
Author / Creator:Melone, Viola ; Salvati, Annamaria ; Palumbo, Domenico ; Giurato, Giorgio ; Nassa, Giovanni ; Rizzo, Francesca ; Palo, Luigi ; Giordano, Alessandro ; Incoronato, Mariarosaria ; Vitale, Mario ; Mian, Caterina ; Di Biase, Immacolata ; Cristiano, Stefano ; Narciso, Viviana ; Cantile, Monica ; Di Mauro, Annabella ; Tatangelo, Fabiana ; Tafuto, Salvatore ; Modica, Roberta ; Pivonello, Claudia ; Salvatore, Marco ; Colao, Annamaria ; Weisz, Alessandro ; Tarallo, Roberta
Publisher:London: BioMed Central Ltd
Journal title:Journal of translational medicine, 2022-07, Vol.20 (1), p.1-306, Article 306
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Global View of Candidate Therapeutic Target Genes in Hormone-Responsive Breast Cancer
Author / Creator:Salvati, Annamaria ; Gigantino, Valerio ; Nassa, Giovanni ; Mirici Cappa, Valeria ; Ventola, Giovanna Maria ; Cracas, Daniela Georgia Cristina ; Mastrocinque, Raffaella ; Rizzo, Francesca ; Tarallo, Roberta ; Weisz, Alessandro ; Giurato, Giorgio
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2020-06, Vol.21 (11), p.4068
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Metabolic Robustness to Growth Temperature of a Cold- Adapted Marine Bacterium
Author / Creator:Riccardi, Christopher ; Calvanese, Marzia ; Ghini, Veronica ; Alonso-Vásquez, Tania ; Perrin, Elena ; Turano, Paola ; Giurato, Giorgio ; Weisz, Alessandro ; Parrilli, Ermenegilda ; Tutino, Maria Luisa ; Fondi, Marco
Publisher:United States: American Society for Microbiology
Journal title:mSystems, 2023-04, Vol.8 (2), p.e0112422-e0112422
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Transcriptomic profiling of calcified aortic valves in clonal hematopoiesis of indeterminate potential carriers
Author / Creator:Vieceli Dalla Sega, Francesco ; Palumbo, Domenico ; Fortini, Francesca ; D’Agostino, Ylenia ; Cimaglia, Paolo ; Marracino, Luisa ; Severi, Paolo ; Strianese, Oriana ; Tarallo, Roberta ; Nassa, Giovanni ; Giurato, Giorgio ; Pecoraro, Giovanni ; Caglioni, Serena ; Mikus, Elisa ; Albertini, Alberto ; Campo, Gianluca ; Ferrari, Roberto ; Rizzo, Paola ; Weisz, Alessandro ; Rizzo, Francesca
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2022-11, Vol.12 (1), p.20400-20400, Article 20400
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Suppression of Spry1 reduces HIF1α-dependent glycolysis and impairs angiogenesis in BRAF-mutant cutaneous melanoma
Author / Creator:Montico, Barbara ; Giurato, Giorgio ; Guerrieri, Roberto ; Colizzi, Francesca ; Salvati, Annamaria ; Nassa, Giovanni ; Lamberti, Jessica ; Memoli, Domenico ; Sabatelli, Patrizia ; Comelli, Marina ; Bellazzo, Arianna ; Fejza, Albina ; Camicia, Lucrezia ; Baboci, Lorena ; Dal Bo, Michele ; Covre, Alessia ; Nyman, Tuula A ; Weisz, Alessandro ; Steffan, Agostino ; Maio, Michele ; Sigalotti, Luca ; Mongiat, Maurizio ; Andreuzzi, Eva ; Fratta, Elisabetta
Publisher:England: BioMed Central
Journal title:Journal of experimental & clinical cancer research, 2025-02, Vol.44 (1), p.53-20
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Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer

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TNF-alpha and metalloproteases as key players in melanoma cells aggressiveness

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Specific gene expression signatures induced by the multiple oncogenic alterations that occur within the PTEN/PI3K/AKT pathway in lung cancer

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BRPF1 inhibition reduces migration and invasion of metastatic ovarian cancer cells, representing a potential therapeutic target

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The nuclear receptor ERβ engages AGO2 in regulation of gene transcription, RNA splicing and RISC loading

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Enhanced ZNF521 expression induces an aggressive phenotype in human ovarian carcinoma cell lines

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Does gut microbiota dysbiosis impact the metabolic alterations of hydrogen sulfide and lanthionine in patients with chronic kidney disease?

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A ZFYVE19 gene mutation associated with neonatal cholestasis and cilia dysfunction: case report with a novel pathogenic variant

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RIZ2 at the crossroad of the EGF/EGFR signaling in colorectal cancer

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Essential gene screening identifies the bromodomain-containing protein BRPF1 as a new actionable target for endocrine therapy-resistant breast cancers

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LncRNA PVT1 links estrogen receptor alpha and the polycomb repressive complex 2 in suppression of pro-apoptotic genes in hormone-responsive breast cancer

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Signaling Networks Associated with AKT Activation in Non-Small Cell Lung Cancer (NSCLC): New Insights on the Role of Phosphatydil-Inositol-3 kinase

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HOME-BIO (sHOtgun MEtagenomic analysis of BIOlogical entities): a specific and comprehensive pipeline for metagenomic shotgun sequencing data analysis

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Circulating SARS-CoV-2 variants in Italy, October 2020–March 2021

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Combinatorial targeting of menin and the histone methyltransferase DOT1L as a novel therapeutic strategy for treatment of chemotherapy-resistant ovarian cancer

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Identification of functional pathways and molecular signatures in neuroendocrine neoplasms by multi-omics analysis

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Global View of Candidate Therapeutic Target Genes in Hormone-Responsive Breast Cancer

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Metabolic Robustness to Growth Temperature of a Cold- Adapted Marine Bacterium

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Transcriptomic profiling of calcified aortic valves in clonal hematopoiesis of indeterminate potential carriers

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Suppression of Spry1 reduces HIF1α-dependent glycolysis and impairs angiogenesis in BRAF-mutant cutaneous melanoma

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