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Wolchok, Jedd D
Journal title:American Men & Women of Science : A Biographical Directory of Today’s Leaders in Physical, Biological and Related Sciences: WIE-ZYW, 2022, p.12420-12420
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Wolchok, Jedd D
Journal title:American Men & Women of Science : A Biographical Directory of Today’s Leaders in Physical, Biological and Related Sciences: WIL-ZYW, 2021, p.12389-12389
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ArticlesPeer ReviewedFull Text
Cancer immunotherapy using checkpoint blockade
Author / Creator:Ribas, Antoni ; Wolchok, Jedd D
Publisher:United States
Journal title:Science (American Association for the Advancement of Science), 2018-03, Vol.359 (6382), p.1350-1355
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Enhancing immunotherapy in cancer by targeting emerging immunomodulatory pathways
Author / Creator:Kraehenbuehl, Lukas ; Weng, Chien-Huan ; Eghbali, Shabnam ; Wolchok, Jedd D. ; Merghoub, Taha
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Clinical oncology, 2022-01, Vol.19 (1), p.37-50
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The future of cancer immunotherapy: microenvironment-targeting combinations
Author / Creator:Murciano-Goroff, Yonina R. ; Warner, Allison Betof ; Wolchok, Jedd D.
Publisher:Singapore: Springer Singapore
Journal title:Cell research, 2020-06, Vol.30 (6), p.507-519
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ArticlesPeer ReviewedFull Text
The future of cancer treatment: immunomodulation, CARs and combination immunotherapy
Author / Creator:Khalil, Danny N. ; Smith, Eric L. ; Brentjens, Renier J. ; Wolchok, Jedd D.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Clinical oncology, 2016-05, Vol.13 (5), p.273-290
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ArticlesPeer ReviewedFull Text
TNF in the era of immune checkpoint inhibitors: friend or foe?
Author / Creator:Chen, Allen Y. ; Wolchok, Jedd D. ; Bass, Anne R.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Rheumatology, 2021-04, Vol.17 (4), p.213-223
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Intestinal microbiome analyses identify melanoma patients at risk for checkpoint-blockade-induced colitis
Author / Creator:Dubin, Krista ; Callahan, Margaret K. ; Ren, Boyu ; Khanin, Raya ; Viale, Agnes ; Ling, Lilan ; No, Daniel ; Gobourne, Asia ; Littmann, Eric ; Huttenhower, Curtis ; Pamer, Eric G. ; Wolchok, Jedd D.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2016-02, Vol.7 (1), p.10391-10391, Article 10391
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ArticlesPeer ReviewedFull Text
Blockade of the AHR restricts a Treg-macrophage suppressive axis induced by L-Kynurenine
Author / Creator:Campesato, Luis Felipe ; Budhu, Sadna ; Tchaicha, Jeremy ; Weng, Chien-Huan ; Gigoux, Mathieu ; Cohen, Ivan Jose ; Redmond, David ; Mangarin, Levi ; Pourpe, Stephane ; Liu, Cailian ; Zappasodi, Roberta ; Zamarin, Dmitriy ; Cavanaugh, Jill ; Castro, Alfredo C. ; Manfredi, Mark G. ; McGovern, Karen ; Merghoub, Taha ; Wolchok, Jedd D.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-08, Vol.11 (1), p.4011-4011, Article 4011
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Nivolumab plus ipilimumab or nivolumab alone versus ipilimumab alone in advanced melanoma (CheckMate 067): 4-year outcomes of a multicentre, randomised, phase 3 trial
Author / Creator:Hodi, Frank Stephen, MD ; Chiarion-Sileni, Vanna, MD ; Gonzalez, Rene, Prof ; Grob, Jean-Jacques, Prof ; Rutkowski, Piotr, Prof ; Cowey, Charles Lance, MD ; Lao, Christopher D, MD ; Schadendorf, Dirk, Prof ; Wagstaff, John, Prof ; Dummer, Reinhard, MD ; Ferrucci, Pier Francesco, MD ; Smylie, Michael, MD ; Hill, Andrew, MD ; Hogg, David, MD ; Marquez-Rodas, Ivan, Prof ; Jiang, Joel, PhD ; Rizzo, Jasmine, MD ; Larkin, James, FRCP ; Wolchok, Jedd D, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2018-11, Vol.19 (11), p.1480-1492
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ArticlesPeer ReviewedFull Text
ILC2s amplify PD-1 blockade by activating tissue-specific cancer immunity
Author / Creator:Moral, John Alec ; Leung, Joanne ; Rojas, Luis A. ; Ruan, Jennifer ; Zhao, Julia ; Sethna, Zachary ; Ramnarain, Anita ; Gasmi, Billel ; Gururajan, Murali ; Redmond, David ; Askan, Gokce ; Bhanot, Umesh ; Elyada, Ela ; Park, Youngkyu ; Tuveson, David A. ; Gönen, Mithat ; Leach, Steven D. ; Wolchok, Jedd D. ; DeMatteo, Ronald P. ; Merghoub, Taha ; Balachandran, Vinod P.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2020-03, Vol.579 (7797), p.130-135
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ArticlesPeer ReviewedFull Text
iRECIST: guidelines for response criteria for use in trials testing immunotherapeutics
Author / Creator:Seymour, Lesley, Prof ; Bogaerts, Jan, PhD ; Perrone, Andrea, MD ; Ford, Robert, MD ; Schwartz, Lawrence H, Prof ; Mandrekar, Sumithra, Prof ; Lin, Nancy U, MD ; Litière, Saskia, PhD ; Dancey, Janet, Prof ; Chen, Alice, MD ; Hodi, F Stephen, Prof ; Therasse, Patrick, MD ; Hoekstra, Otto S, Prof ; Shankar, Lalitha K, MD ; Wolchok, Jedd D, MD ; Ballinger, Marcus, PhD ; Caramella, Caroline, MD ; de Vries, Elisabeth G E, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2017-03, Vol.18 (3), p.e143-e152
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ArticlesPeer ReviewedFull Text
Mutational landscape determines sensitivity to PD-1 blockade in non–small cell lung cancer
Author / Creator:Rizvi, Naiyer A. ; Hellmann, Matthew D. ; Snyder, Alexandra ; Kvistborg, Pia ; Makarov, Vladimir ; Havel, Jonathan J. ; Lee, William ; Yuan, Jianda ; Wong, Phillip ; Ho, Teresa S. ; Miller, Martin L. ; Rekhtman, Natasha ; Moreira, Andre L. ; Ibrahim, Fawzia ; Bruggeman, Cameron ; Gasmi, Billel ; Zappasodi, Roberta ; Maeda, Yuka ; Sander, Chris ; Garon, Edward B. ; Merghoub, Taha ; Wolchok, Jedd D. ; Schumacher, Ton N. ; Chan, Timothy A.
Publisher:Washington: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2015-04, Vol.348 (6230), p.124-128
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ArticlesPeer ReviewedFull Text
Genetic Basis for Clinical Response to CTLA-4 Blockade in Melanoma
Author / Creator:Snyder, Alexandra ; Makarov, Vladimir ; Merghoub, Taha ; Yuan, Jianda ; Zaretsky, Jesse M ; Desrichard, Alexis ; Walsh, Logan A ; Postow, Michael A ; Wong, Phillip ; Ho, Teresa S ; Hollmann, Travis J ; Bruggeman, Cameron ; Kannan, Kasthuri ; Li, Yanyun ; Elipenahli, Ceyhan ; Liu, Cailian ; Harbison, Christopher T ; Wang, Lisu ; Ribas, Antoni ; Wolchok, Jedd D ; Chan, Timothy A
Publisher:Waltham, MA: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2014-12, Vol.371 (23), p.2189-2199
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ArticlesPeer ReviewedFull Text
Rational design of anti-GITR-based combination immunotherapy
Author / Creator:Zappasodi, Roberta ; Sirard, Cynthia ; Li, Yanyun ; Budhu, Sadna ; Abu-Akeel, Mohsen ; Liu, Cailian ; Yang, Xia ; Zhong, Hong ; Newman, Walter ; Qi, Jingjing ; Wong, Phillip ; Schaer, David ; Koon, Henry ; Velcheti, Vamsidhar ; Hellmann, Matthew D. ; Postow, Michael A. ; Callahan, Margaret K. ; Wolchok, Jedd D. ; Merghoub, Taha
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2019-05, Vol.25 (5), p.759-766
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ArticlesPeer ReviewedFull Text
Combined nivolumab and ipilimumab versus ipilimumab alone in patients with advanced melanoma: 2-year overall survival outcomes in a multicentre, randomised, controlled, phase 2 trial
Author / Creator:Hodi, F Stephen, Dr ; Chesney, Jason, Prof ; Pavlick, Anna C, MD ; Robert, Caroline, Prof ; Grossmann, Kenneth F, MD ; McDermott, David F, MD ; Linette, Gerald P, MD ; Meyer, Nicolas, Prof ; Giguere, Jeffrey K, MD ; Agarwala, Sanjiv S, Prof ; Shaheen, Montaser, MD ; Ernstoff, Marc S, Prof ; Minor, David R, MD ; Salama, April K, MD ; Taylor, Matthew H, MD ; Ott, Patrick A, MD ; Horak, Christine, PhD ; Gagnier, Paul, MD ; Jiang, Joel, PhD ; Wolchok, Jedd D, Prof ; Postow, Michael A, MD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2016-11, Vol.17 (11), p.1558-1568
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Adjuvant ipilimumab versus placebo after complete resection of high-risk stage III melanoma (EORTC 18071): a randomised, double-blind, phase 3 trial
Author / Creator:Eggermont, Alexander M M, Prof ; Chiarion-Sileni, Vanna, MD ; Grob, Jean-Jacques, Prof ; Dummer, Reinhard, Prof ; Wolchok, Jedd D, MD ; Schmidt, Henrik, MD ; Hamid, Omid, MD ; Robert, Caroline, Prof ; Ascierto, Paolo A, Prof ; Richards, Jon M, MD ; Lebbé, Céleste, Prof ; Ferraresi, Virginia, MD ; Smylie, Michael, MD ; Weber, Jeffrey S, MD ; Maio, Michele, MD ; Konto, Cyril, MD ; Hoos, Axel, MD ; de Pril, Veerle, MSc ; Gurunath, Ravichandra Karra, MD ; de Schaetzen, Gaetan, PhD ; Suciu, Stefan, PhD ; Testori, Alessandro, MD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2015-05, Vol.16 (5), p.522-530
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PD-L1 in tumor microenvironment mediates resistance to oncolytic immunotherapy
Author / Creator:Zamarin, Dmitriy ; Ricca, Jacob M. ; Sadekova, Svetlana ; Oseledchyk, Anton ; Yu, Ying ; Blumenschein, Wendy M. ; Wong, Jerelyn ; Gigoux, Mathieu ; Merghoub, Taha ; Wolchok, Jedd D.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2018-04, Vol.128 (4), p.1413-1428
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Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET
Author / Creator:Peinado, Héctor ; Alečković, Maša ; Lavotshkin, Simon ; Matei, Irina ; Costa-Silva, Bruno ; Moreno-Bueno, Gema ; Hergueta-Redondo, Marta ; Williams, Caitlin ; García-Santos, Guillermo ; Ghajar, Cyrus M ; Nitadori-Hoshino, Ayuko ; Hoffman, Caitlin ; Badal, Karen ; Garcia, Benjamin A ; Callahan, Margaret K ; Yuan, Jianda ; Martins, Vilma R ; Skog, Johan ; Kaplan, Rosandra N ; Brady, Mary S ; Wolchok, Jedd D ; Chapman, Paul B ; Kang, Yibin ; Bromberg, Jacqueline ; Lyden, David
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2012-06, Vol.18 (6), p.883-891
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ArticlesPeer ReviewedFull Text
Intratumoral modulation of the inducible co-stimulator ICOS by recombinant oncolytic virus promotes systemic anti-tumour immunity
Author / Creator:Zamarin, Dmitriy ; Holmgaard, Rikke B. ; Ricca, Jacob ; Plitt, Tamar ; Palese, Peter ; Sharma, Padmanee ; Merghoub, Taha ; Wolchok, Jedd D. ; Allison, James P.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-02, Vol.8 (1), p.14340-14340, Article 14340
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Wolchok, Jedd D

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Wolchok, Jedd D

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Cancer immunotherapy using checkpoint blockade

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Enhancing immunotherapy in cancer by targeting emerging immunomodulatory pathways

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The future of cancer immunotherapy: microenvironment-targeting combinations

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The future of cancer treatment: immunomodulation, CARs and combination immunotherapy

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TNF in the era of immune checkpoint inhibitors: friend or foe?

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Intestinal microbiome analyses identify melanoma patients at risk for checkpoint-blockade-induced colitis

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Blockade of the AHR restricts a Treg-macrophage suppressive axis induced by L-Kynurenine

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Nivolumab plus ipilimumab or nivolumab alone versus ipilimumab alone in advanced melanoma (CheckMate 067): 4-year outcomes of a multicentre, randomised, phase 3 trial

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ILC2s amplify PD-1 blockade by activating tissue-specific cancer immunity

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iRECIST: guidelines for response criteria for use in trials testing immunotherapeutics

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Mutational landscape determines sensitivity to PD-1 blockade in non–small cell lung cancer

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Genetic Basis for Clinical Response to CTLA-4 Blockade in Melanoma

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Rational design of anti-GITR-based combination immunotherapy

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Combined nivolumab and ipilimumab versus ipilimumab alone in patients with advanced melanoma: 2-year overall survival outcomes in a multicentre, randomised, controlled, phase 2 trial

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Adjuvant ipilimumab versus placebo after complete resection of high-risk stage III melanoma (EORTC 18071): a randomised, double-blind, phase 3 trial

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PD-L1 in tumor microenvironment mediates resistance to oncolytic immunotherapy

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Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

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Intratumoral modulation of the inducible co-stimulator ICOS by recombinant oncolytic virus promotes systemic anti-tumour immunity

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