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A computational tool (H-MAGMA) for improved prediction of brain-disorder risk genes by incorporating brain chromatin interaction profiles
Author / Creator:Sey, Nancy Y. A. ; Hu, Benxia ; Mah, Won ; Fauni, Harper ; McAfee, Jessica Caitlin ; Rajarajan, Prashanth ; Brennand, Kristen J. ; Akbarian, Schahram ; Won, Hyejung
Publisher:New York: Nature Publishing Group US
Journal title:Nature neuroscience, 2020-04, Vol.23 (4), p.583-593
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Human evolved regulatory elements modulate genes involved in cortical expansion and neurodevelopmental disease susceptibility
Author / Creator:Won, Hyejung ; Huang, Jerry ; Opland, Carli K. ; Hartl, Chris L. ; Geschwind, Daniel H.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-06, Vol.10 (1), p.2396-2396, Article 2396
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Advancing the understanding of autism disease mechanisms through genetics
Author / Creator:de la Torre-Ubieta, Luis ; Won, Hyejung ; Stein, Jason L ; Geschwind, Daniel H
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2016-04, Vol.22 (4), p.345-361
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Chromatin architecture provides a roadmap to improve our understanding of psychiatric disorders
Author / Creator:Hu, Benxia ; Won, Hyejung
Publisher:England: Nature Publishing Group
Journal title:Neuropsychopharmacology (New York, N.Y.), 2021-01, Vol.46 (1), p.234-235
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Chromosome conformation elucidates regulatory relationships in developing human brain
Author / Creator:Won, Hyejung ; de la Torre-Ubieta, Luis ; Stein, Jason L. ; Parikshak, Neelroop N. ; Huang, Jerry ; Opland, Carli K. ; Gandal, Michael J. ; Sutton, Gavin J. ; Hormozdiari, Farhad ; Lu, Daning ; Lee, Changhoon ; Eskin, Eleazar ; Voineagu, Irina ; Ernst, Jason ; Geschwind, Daniel H.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2016-10, Vol.538 (7626), p.523-527
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Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights
Author / Creator:Gusev, Alexander ; Mancuso, Nicholas ; Won, Hyejung ; Kousi, Maria ; Finucane, Hilary K. ; Reshef, Yakir ; Song, Lingyun ; Safi, Alexias ; McCarroll, Steven ; Neale, Benjamin M. ; Ophoff, Roel A. ; O’Donovan, Michael C. ; Crawford, Gregory E. ; Geschwind, Daniel H. ; Katsanis, Nicholas ; Sullivan, Patrick F. ; Pasaniuc, Bogdan ; Price, Alkes L.
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2018-04, Vol.50 (4), p.538-548
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De novo mutations in regulatory elements in neurodevelopmental disorders
Author / Creator:Short, Patrick J. ; McRae, Jeremy F. ; Gallone, Giuseppe ; Sifrim, Alejandro ; Won, Hyejung ; Geschwind, Daniel H. ; Wright, Caroline F. ; Firth, Helen V. ; FitzPatrick, David R. ; Barrett, Jeffrey C. ; Hurles, Matthew E.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2018-03, Vol.555 (7698), p.611-616
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Integrative genomics identifies a convergent molecular subtype that links epigenomic with transcriptomic differences in autism
Author / Creator:Ramaswami, Gokul ; Won, Hyejung ; Gandal, Michael J. ; Haney, Jillian ; Wang, Jerry C. ; Wong, Chloe C. Y. ; Sun, Wenjie ; Prabhakar, Shyam ; Mill, Jonathan ; Geschwind, Daniel H.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-09, Vol.11 (1), p.4873-4873, Article 4873
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Neuron-specific signatures in the chromosomal connectome associated with schizophrenia risk
Author / Creator:Rajarajan, Prashanth ; Borrman, Tyler ; Liao, Will ; Schrode, Nadine ; Flaherty, Erin ; Casiño, Charlize ; Powell, Samuel ; Yashaswini, Chittampalli ; LaMarca, Elizabeth A. ; Kassim, Bibi ; Javidfar, Behnam ; Espeso-Gil, Sergio ; Li, Aiqun ; Won, Hyejung ; Geschwind, Daniel H. ; Ho, Seok-Man ; MacDonald, Matthew ; Hoffman, Gabriel E. ; Roussos, Panos ; Zhang, Bin ; Hahn, Chang-Gyu ; Weng, Zhiping ; Brennand, Kristen J. ; Akbarian, Schahram
Publisher:United States: The American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2018-12, Vol.362 (6420)
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A genome-wide association study of shared risk across psychiatric disorders implicates gene regulation during fetal neurodevelopment
Author / Creator:Schork, Andrew J. ; Won, Hyejung ; Appadurai, Vivek ; Nudel, Ron ; Gandal, Mike ; Delaneau, Olivier ; Revsbech Christiansen, Malene ; Hougaard, David M. ; Bækved-Hansen, Marie ; Bybjerg-Grauholm, Jonas ; Giørtz Pedersen, Marianne ; Agerbo, Esben ; Bøcker Pedersen, Carsten ; Neale, Benjamin M. ; Daly, Mark J. ; Wray, Naomi R. ; Nordentoft, Merete ; Mors, Ole ; Børglum, Anders D. ; Bo Mortensen, Preben ; Buil, Alfonso ; Thompson, Wesley K. ; Geschwind, Daniel H. ; Werge, Thomas
Publisher:New York: Nature Publishing Group US
Journal title:Nature neuroscience, 2019-03, Vol.22 (3), p.353-361
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Common genetic risk variants identified in the SPARK cohort support DDHD2 as a candidate risk gene for autism
Author / Creator:Matoba, Nana ; Liang, Dan ; Sun, Huaigu ; Aygün, Nil ; McAfee, Jessica C. ; Davis, Jessica E. ; Raffield, Laura M. ; Qian, Huijun ; Piven, Joseph ; Li, Yun ; Kosuri, Sriam ; Won, Hyejung ; Stein, Jason L.
Publisher:London: Nature Publishing Group UK
Journal title:Translational psychiatry, 2020-08, Vol.10 (1), p.265-265, Article 265
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The genetic relationships between brain structure and schizophrenia
Author / Creator:Stauffer, Eva-Maria ; Bethlehem, Richard A. I. ; Dorfschmidt, Lena ; Won, Hyejung ; Warrier, Varun ; Bullmore, Edward T.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-11, Vol.14 (1), p.7820-15, Article 7820
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Expanding the genetic architecture of nicotine dependence and its shared genetics with multiple traits
Author / Creator:Quach, Bryan C. ; Bray, Michael J. ; Gaddis, Nathan C. ; Liu, Mengzhen ; Palviainen, Teemu ; Minica, Camelia C. ; Zellers, Stephanie ; Sherva, Richard ; Aliev, Fazil ; Nothnagel, Michael ; Young, Kendra A. ; Marks, Jesse A. ; Young, Hannah ; Carnes, Megan U. ; Guo, Yuelong ; Waldrop, Alex ; Sey, Nancy Y. A. ; Landi, Maria T. ; McNeil, Daniel W. ; Drichel, Dmitriy ; Farrer, Lindsay A. ; Markunas, Christina A. ; Vink, Jacqueline M. ; Hottenga, Jouke-Jan ; Iacono, William G. ; Kranzler, Henry R. ; Saccone, Nancy L. ; Neale, Michael C. ; Madden, Pamela ; Rietschel, Marcella ; Marazita, Mary L. ; McGue, Matthew ; Won, Hyejung ; Winterer, Georg ; Grucza, Richard ; Dick, Danielle M. ; Gelernter, Joel ; Caporaso, Neil E. ; Baker, Timothy B. ; Boomsma, Dorret I. ; Kaprio, Jaakko ; Hokanson, John E. ; Vrieze, Scott ; Bierut, Laura J. ; Johnson, Eric O. ; Hancock, Dana B.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-11, Vol.11 (1), p.5562-13, Article 5562
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Illuminating links between cis-regulators and trans-acting variants in the human prefrontal cortex
Author / Creator:Liu, Shuang ; Won, Hyejung ; Clarke, Declan ; Matoba, Nana ; Khullar, Saniya ; Mu, Yudi ; Wang, Daifeng ; Gerstein, Mark
Publisher:England: BioMed Central Ltd
Journal title:Genome medicine, 2022-11, Vol.14 (1), p.133-133, Article 133
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Etiologic heterogeneity, pleiotropy, and polygenicity in behaviorally defined intellectual and developmental disabilities
Author / Creator:Girault, Jessica B. ; Veatch, Olivia J. ; Won, Hyejung
Publisher:England: BioMed Central Ltd
Journal title:Journal of neurodevelopmental disorders, 2024-03, Vol.16 (1), p.8-4, Article 8
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Focus on your locus with a massively parallel reporter assay
Author / Creator:McAfee, Jessica C. ; Bell, Jessica L. ; Krupa, Oleh ; Matoba, Nana ; Stein, Jason L. ; Won, Hyejung
Publisher:England: BioMed Central Ltd
Journal title:Journal of neurodevelopmental disorders, 2022-09, Vol.14 (1), p.50-14, Article 50
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Social and non-social autism symptoms and trait domains are genetically dissociable
Author / Creator:Warrier, Varun ; Toro, Roberto ; Won, Hyejung ; Leblond, Claire S. ; Cliquet, Freddy ; Delorme, Richard ; De Witte, Ward ; Bralten, Janita ; Chakrabarti, Bhismadev ; Børglum, Anders D. ; Grove, Jakob ; Poelmans, Geert ; Hinds, David A. ; Bourgeron, Thomas ; Baron-Cohen, Simon
Publisher:London: Nature Publishing Group UK
Journal title:Communications biology, 2019-09, Vol.2 (1), p.328, Article 328
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Joint genome-wide association study of progressive supranuclear palsy identifies novel susceptibility loci and genetic correlation to neurodegenerative diseases
Author / Creator:Chen, Jason A. ; Chen, Zhongbo ; Won, Hyejung ; Huang, Alden Y. ; Lowe, Jennifer K. ; Wojta, Kevin ; Yokoyama, Jennifer S. ; Bensimon, Gilbert ; Leigh, P. Nigel ; Payan, Christine ; Shatunov, Aleksey ; Jones, Ashley R. ; Lewis, Cathryn M. ; Deloukas, Panagiotis ; Amouyel, Philippe ; Tzourio, Christophe ; Dartigues, Jean-Francois ; Ludolph, Albert ; Boxer, Adam L. ; Bronstein, Jeff M. ; Al-Chalabi, Ammar ; Geschwind, Daniel H. ; Coppola, Giovanni
Publisher:England: BioMed Central Ltd
Journal title:Molecular neurodegeneration, 2018-08, Vol.13 (1), p.41-41, Article 41
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Correction: Chromatin architecture in addiction circuitry identifies risk genes and potential biological mechanisms underlying cigarette smoking and alcohol use traits
Author / Creator:Sey, Nancy Y. A. ; Hu, Benxia ; Iskhakova, Marina ; Lee, Sool ; Sun, Huaigu ; Shokrian, Neda ; Ben Hutta, Gabriella ; Marks, Jesse A. ; Quach, Bryan C. ; Johnson, Eric O. ; Hancock, Dana B. ; Akbarian, Schahram ; Won, Hyejung
Publisher:London: Nature Publishing Group UK
Journal title:Molecular psychiatry, 2022-10, Vol.27 (10), p.4368-4368
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Selection on the regulation of sympathetic nervous activity in humans and chimpanzees
Author / Creator:Lee, Kang Seon ; Chatterjee, Paramita ; Choi, Eun-Young ; Sung, Min Kyung ; Oh, Jaeho ; Won, Hyejung ; Park, Seong-Min ; Kim, Youn-Jae ; Yi, Soojin V. ; Choi, Jung Kyoon
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2018-04, Vol.14 (4), p.e1007311-e1007311
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A computational tool (H-MAGMA) for improved prediction of brain-disorder risk genes by incorporating brain chromatin interaction profiles

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Human evolved regulatory elements modulate genes involved in cortical expansion and neurodevelopmental disease susceptibility

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Advancing the understanding of autism disease mechanisms through genetics

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Chromatin architecture provides a roadmap to improve our understanding of psychiatric disorders

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Chromosome conformation elucidates regulatory relationships in developing human brain

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Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights

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De novo mutations in regulatory elements in neurodevelopmental disorders

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Integrative genomics identifies a convergent molecular subtype that links epigenomic with transcriptomic differences in autism

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Neuron-specific signatures in the chromosomal connectome associated with schizophrenia risk

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A genome-wide association study of shared risk across psychiatric disorders implicates gene regulation during fetal neurodevelopment

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Common genetic risk variants identified in the SPARK cohort support DDHD2 as a candidate risk gene for autism

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The genetic relationships between brain structure and schizophrenia

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Expanding the genetic architecture of nicotine dependence and its shared genetics with multiple traits

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Illuminating links between cis-regulators and trans-acting variants in the human prefrontal cortex

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Etiologic heterogeneity, pleiotropy, and polygenicity in behaviorally defined intellectual and developmental disabilities

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Focus on your locus with a massively parallel reporter assay

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Social and non-social autism symptoms and trait domains are genetically dissociable

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Joint genome-wide association study of progressive supranuclear palsy identifies novel susceptibility loci and genetic correlation to neurodegenerative diseases

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Correction: Chromatin architecture in addiction circuitry identifies risk genes and potential biological mechanisms underlying cigarette smoking and alcohol use traits

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Selection on the regulation of sympathetic nervous activity in humans and chimpanzees

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