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The KEYNOTE-811 trial of dual PD-1 and HER2 blockade in HER2-positive gastric cancer
Author / Creator:Janjigian, Yelena Y. ; Kawazoe, Akihito ; Yañez, Patricio ; Li, Ning ; Lonardi, Sara ; Kolesnik, Oleksii ; Barajas, Olga ; Bai, Yuxian ; Shen, Lin ; Tang, Yong ; Wyrwicz, Lucjan S. ; Xu, Jianming ; Shitara, Kohei ; Qin, Shukui ; Van Cutsem, Eric ; Tabernero, Josep ; Li, Lie ; Shah, Sukrut ; Bhagia, Pooja ; Chung, Hyun Cheol
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2021-12, Vol.600 (7890), p.727-730
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Pembrolizumab plus trastuzumab and chemotherapy for HER2-positive gastric or gastro-oesophageal junction adenocarcinoma: interim analyses from the phase 3 KEYNOTE-811 randomised placebo-controlled tri...
Author / Creator:Janjigian, Yelena Y ; Kawazoe, Akihito ; Bai, Yuxian ; Xu, Jianming ; Lonardi, Sara ; Metges, Jean Phillipe ; Yanez, Patricio ; Wyrwicz, Lucjan S ; Shen, Lin ; Ostapenko, Yuriy ; Bilici, Mehmet ; Chung, Hyun Cheol ; Shitara, Kohei ; Qin, Shu-Kui ; Van Cutsem, Eric ; Tabernero, Josep ; Li, Kan ; Shih, Chie-Schin ; Bhagia, Pooja ; Rha, Sun Young
Publisher:England: Elsevier Limited
Journal title:The Lancet (British edition), 2023-12, Vol.402 (10418), p.2197-2208
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Trifluridine–Tipiracil and Bevacizumab in Refractory Metastatic Colorectal Cancer
Author / Creator:Prager, Gerald W. ; Taieb, Julien ; Fakih, Marwan ; Ciardiello, Fortunato ; Van Cutsem, Eric ; Elez, Elena ; Cruz, Felipe M. ; Wyrwicz, Lucjan ; Stroyakovskiy, Daniil ; Pápai, Zsuzsanna ; Poureau, Pierre-Guillaume ; Liposits, Gabor ; Cremolini, Chiara ; Bondarenko, Igor ; Modest, Dominik P. ; Benhadji, Karim A. ; Amellal, Nadia ; Leger, Catherine ; Vidot, Loïck ; Tabernero, Josep
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2023-05, Vol.388 (18), p.1657-1667
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Nivolumab versus sorafenib in advanced hepatocellular carcinoma (CheckMate 459): a randomised, multicentre, open-label, phase 3 trial
Author / Creator:Yau, Thomas, MD ; Park, Joong-Won, MD ; Finn, Richard S, Prof ; Cheng, Ann-Lii, Prof ; Mathurin, Philippe, Prof ; Edeline, Julien, MD ; Kudo, Masatoshi, Prof ; Harding, James J, MD ; Merle, Philippe, Prof ; Rosmorduc, Olivier, Prof ; Wyrwicz, Lucjan, Prof ; Schott, Eckart, Prof ; Choo, Su Pin, MD ; Kelley, Robin Kate, Prof ; Sieghart, Wolfgang, MD ; Assenat, Eric, Prof ; Zaucha, Renata, Prof ; Furuse, Junji, Prof ; Abou-Alfa, Ghassan K, MD ; El-Khoueiry, Anthony B, MD ; Melero, Ignacio, Prof ; Begic, Damir, PharmD ; Chen, Gong, PhD ; Neely, Jaclyn, PhD ; Wisniewski, Tami, MPH ; Tschaika, Marina, MD ; Sangro, Bruno, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2022, Vol.23 (1), p.77-90
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Neoadjuvant and adjuvant pembrolizumab plus chemotherapy in locally advanced gastric or gastro-oesophageal cancer (KEYNOTE-585): an interim analysis of the multicentre, double-blind, randomised phase...
Author / Creator:Shitara, Kohei, MD ; Rha, Sun Young, Prof ; Wyrwicz, Lucjan S, Prof ; Oshima, Takashi, MD ; Karaseva, Nina, MD ; Osipov, Mikhail, MD ; Yasui, Hisateru, MD ; Yabusaki, Hiroshi, MD ; Afanasyev, Sergey, MD ; Park, Young-Kyu, MD ; Al-Batran, Salah-Eddin, MD ; Yoshikawa, Takaki, MD ; Yanez, Patricio, MD ; Di Bartolomeo, Maria, MD ; Lonardi, Sara, MD ; Tabernero, Josep, Prof ; Van Cutsem, Eric, Prof ; Janjigian, Yelena Y, MD ; Oh, Do-Youn, Prof ; Xu, Jianming, MD ; Fang, Xiao, PhD ; Shih, Chie-Schin, MD ; Bhagia, Pooja, MD ; Bang, Yung-Jue, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2024-02, Vol.25 (2), p.212-224
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Tislelizumab plus chemotherapy versus placebo plus chemotherapy as first-line treatment for advanced or metastatic oesophageal squamous cell carcinoma (RATIONALE-306): a global, randomised, placebo-co...
Author / Creator:Xu, Jianming, Prof ; Kato, Ken, MD ; Raymond, Eric, Prof ; Hubner, Richard A, BM BCh ; Shu, Yongqian, Prof ; Pan, Yueyin, Prof ; Park, Sook Ryun, Prof ; Ping, Lu, MD ; Jiang, Yi, MD ; Zhang, Jingdong, Prof ; Wu, Xiaohong, MD ; Yao, Yuanhu, MD ; Shen, Lin, Prof ; Kojima, Takashi, Prof ; Gotovkin, Evgeny, MD ; Ishihara, Ryu, MD ; Wyrwicz, Lucjan, Prof ; Van Cutsem, Eric, Prof ; Jimenez-Fonseca, Paula, MD ; Lin, Chen-Yuan, MD ; Wang, Lei, MD ; Shi, Jingwen, PhD ; Li, Liyun, MD ; Yoon, Harry H, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2023-05, Vol.24 (5), p.483-495
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Correlation between Lymphocyte-to-Monocyte Ratio (LMR), Neutrophil-to-Lymphocyte Ratio (NLR), Platelet-to-Lymphocyte Ratio (PLR) and Extramural Vascular Invasion (EMVI) in Locally Advanced Rectal Canc...
Author / Creator:Gawiński, Cieszymierz ; Hołdakowska, Anna ; Wyrwicz, Lucjan
Publisher:Switzerland: MDPI
Journal title:Current oncology (Toronto), 2022-12, Vol.30 (1), p.545-558
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Correlation between Lymphocyte-to-Monocyte Ratio (LMR), Neutrophil-to-Lymphocyte Ratio (NLR), Platelet-to-Lymphocyte Ratio (PLR) and Tumor-Infiltrating Lymphocytes (TILs) in Left-Sided Colorectal Canc...
Author / Creator:Gawiński, Cieszymierz ; Michalski, Wojciech ; Mróz, Andrzej ; Wyrwicz, Lucjan
Publisher:Switzerland: MDPI AG
Journal title:Biology (Basel, Switzerland), 2022-02, Vol.11 (3), p.385
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MABp1 as a novel antibody treatment for advanced colorectal cancer: a randomised, double-blind, placebo-controlled, phase 3 study
Author / Creator:Hickish, Tamas, Dr ; Andre, Thierry, MD ; Wyrwicz, Lucjan, MD ; Saunders, Mark, MBBS ; Sarosiek, Tomasz, MD ; Kocsis, Judit, MD ; Nemecek, Radim, MD ; Rogowski, Wojciech, MD ; Lesniewski-Kmak, Krzysztof, MD ; Petruzelka, Lubos, MD ; Apte, Ron N, PhD ; Mohanty, Prasant, MBBS ; Stecher, Michael, MD ; Simard, John, BS ; de Gramont, Aimery, MD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2017-02, Vol.18 (2), p.192-201
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Pembrolizumab in HER2-Positive Gastric Cancer
Author / Creator:Janjigian, Yelena Y. ; Kawazoe, Akihito ; Bai, Yuxian ; Xu, Jianming ; Lonardi, Sara ; Metges, Jean Phillipe ; Yañez, Patricio ; Wyrwicz, Lucjan S. ; Shen, Lin ; Ostapenko, Yuriy ; Bilici, Mehmet ; Chung, Hyun Cheol ; Shitara, Kohei ; Qin, Shukui ; Van Cutsem, Eric ; Tabernero, Josep ; Luo, Suxia ; Mahave, Mauricio ; Tang, Yong ; Lowery, Maeve ; Monteiro, Maria M.F. ; Xu, Linzhi ; Shih, Chie-Schin ; Sharan, Kanu P. ; Bhagia, Pooja ; Rha, Sun Young
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2024-10, Vol.391 (14), p.1360-1362
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Safety and efficacy of trifluridine/tipiracil in previously treated metastatic colorectal cancer: final results from the phase IIIb single-arm PRECONNECT study by duration of therapy
Author / Creator:Taieb, Julien ; Price, Timothy ; Vidot, Loïck ; Chevallier, Bénédicte ; Wyrwicz, Lucjan ; Bachet, Jean-Baptiste
Publisher:England: BioMed Central Ltd
Journal title:BMC cancer, 2023-01, Vol.23 (1), p.94-11, Article 94
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Safety and efficacy of lenvatinib by starting dose based on body weight in patients with unresectable hepatocellular carcinoma in REFLECT
Author / Creator:Okusaka, Takuji ; Ikeda, Kenji ; Kudo, Masatoshi ; Finn, Richard ; Qin, Shukui ; Han, Kwang-Hyub ; Cheng, Ann-Lii ; Piscaglia, Fabio ; Kobayashi, Masahiro ; Sung, Max ; Chen, Minshan ; Wyrwicz, Lucjan ; Yoon, Jung-Hwan ; Ren, Zhenggang ; Mody, Kalgi ; Dutcus, Corina ; Tamai, Toshiyuki ; Ren, Min ; Hayato, Seiichi ; Kumada, Hiromitsu
Publisher:Singapore: Springer Singapore
Journal title:Journal of gastroenterology, 2021-06, Vol.56 (6), p.570-580
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Highlights from ASCO-GI 2021 from EORTC Gastrointestinal tract cancer group
Author / Creator:Koessler Thibaud ; Alsina, Maria ; Arnold, Dirk ; Ben-Aharon, Irit ; Lutz, Manfred P ; Obermannova Radka ; Peeters, Mark ; Sclafani, Francesco ; Smyth, Elizabeth ; Valle, Juan W ; Wagner, Anna Dorothea ; Wyrwicz Lucjan ; Fontana, Elisa ; Moehler Markus
Publisher:London: Nature Publishing Group
Journal title:British journal of cancer, 2021-09, Vol.125 (7), p.911-919
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A Prospective Study on the Roles of the Lymphocyte-to-Monocyte Ratio (LMR), Neutrophil-to-Lymphocyte Ratio (NLR), and Platelet-to-Lymphocyte Ratio (PLR) in Patients with Locally Advanced Rectal Cancer
Author / Creator:Gawiński, Cieszymierz ; Mróz, Andrzej ; Roszkowska-Purska, Katarzyna ; Sosnowska, Iwona ; Derezińska-Wołek, Edyta ; Michalski, Wojciech ; Wyrwicz, Lucjan
Publisher:Basel: MDPI AG
Journal title:Biomedicines, 2023-11, Vol.11 (11), p.3048
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Avelumab in patients with previously treated metastatic melanoma: phase 1b results from the JAVELIN Solid Tumor trial
Author / Creator:Keilholz, Ulrich ; Mehnert, Janice M. ; Bauer, Sebastian ; Bourgeois, Hugues ; Patel, Manish R. ; Gravenor, Donald ; Nemunaitis, John J. ; Taylor, Matthew H. ; Wyrwicz, Lucjan ; Lee, Keun-Wook ; Kasturi, Vijay ; Chin, Kevin ; von Heydebreck, Anja ; Gulley, James L.
Publisher:England: BioMed Central Ltd
Journal title:Journal for immunotherapy of cancer, 2019-01, Vol.7 (1), p.12-13, Article 12
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Nivolumab plus chemotherapy or ipilimumab versus chemotherapy in patients with advanced esophageal squamous cell carcinoma (CheckMate 648): 29‐month follow‐up from a randomized, open‐label, phase III...
Author / Creator:Kato, Ken ; Doki, Yuichiro ; Chau, Ian ; Xu, Jianming ; Wyrwicz, Lucjan ; Motoyama, Satoru ; Ogata, Takashi ; Kawakami, Hisato ; Hsu, Chih‐Hung ; Adenis, Antoine ; El Hajbi, Farid ; Di Bartolomeo, Maria ; Braghiroli, Maria Ignez ; Holtved, Eva ; Makino, Tomoki ; Blum Murphy, Mariela ; Amaya‐Chanaga, Carlos ; Patel, Apurva ; Hu, Nan ; Matsumura, Yasuhiro ; Kitagawa, Yuko ; Ajani, Jaffer
Publisher:United States: John Wiley & Sons, Inc
Journal title:Cancer medicine (Malden, MA), 2024-05, Vol.13 (9), p.e7235-n/a
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Avelumab (anti–PD-L1) as first-line switch-maintenance or second-line therapy in patients with advanced gastric or gastroesophageal junction cancer: phase 1b results from the JAVELIN Solid Tumor trial
Author / Creator:Chung, Hyun Cheol ; Arkenau, Hendrik-Tobias ; Lee, Jeeyun ; Rha, Sun Young ; Oh, Do-Youn ; Wyrwicz, Lucjan ; Kang, Yoon-Koo ; Lee, Keun-Wook ; Infante, Jeffrey R. ; Lee, Sung Sook ; Kemeny, Margaret ; Keilholz, Ulrich ; Melichar, Bohuslav ; Mita, Alain ; Plummer, Ruth ; Smith, Denis ; Gelb, Arnold B. ; Xiong, Huiling ; Hong, Janet ; Chand, Vikram ; Safran, Howard
Publisher:England: BioMed Central Ltd
Journal title:Journal for immunotherapy of cancer, 2019-02, Vol.7 (1), p.30-10, Article 30
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Growth Rate of Paragangliomas Related to Germline Mutations of the SDHx Genes
Author / Creator:Michałowska, Ilona ; Ćwikła, Jarosław ; Michalski, Wojciech ; Wyrwicz, Lucjan S. ; Prejbisz, Aleksander ; Szperl, Małgorzata ; Nieć, Dawid ; Neumann, Hartmut P.H. ; Januszewicz, Andrzej ; Pęczkowska, Mariola
Publisher:United States: Elsevier Limited
Journal title:Endocrine practice, 2017-03, Vol.23 (3), p.342-352
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ShapeGTB: the role of local DNA shape in prioritization of functional variants in human promoters with machine learning
Author / Creator:Malkowska, Maja ; Zubek, Julian ; Plewczynski, Dariusz ; Wyrwicz, Lucjan S.
Publisher:United States: PeerJ. Ltd
Journal title:PeerJ (San Francisco, CA), 2018-11, Vol.6, p.e5742, Article e5742
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Integrating genomics, proteomics and bioinformatics in translational studies of molecular medicine
Author / Creator:Ostrowski, Jerzy ; Wyrwicz, Lucjan S
Publisher:England: Taylor & Francis
Journal title:Expert review of molecular diagnostics, 2009-09, Vol.9 (6), p.623-630
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The KEYNOTE-811 trial of dual PD-1 and HER2 blockade in HER2-positive gastric cancer

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Pembrolizumab plus trastuzumab and chemotherapy for HER2-positive gastric or gastro-oesophageal junction adenocarcinoma: interim analyses from the phase 3 KEYNOTE-811 randomised placebo-controlled tri...

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Trifluridine–Tipiracil and Bevacizumab in Refractory Metastatic Colorectal Cancer

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Nivolumab versus sorafenib in advanced hepatocellular carcinoma (CheckMate 459): a randomised, multicentre, open-label, phase 3 trial

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Neoadjuvant and adjuvant pembrolizumab plus chemotherapy in locally advanced gastric or gastro-oesophageal cancer (KEYNOTE-585): an interim analysis of the multicentre, double-blind, randomised phase...

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Tislelizumab plus chemotherapy versus placebo plus chemotherapy as first-line treatment for advanced or metastatic oesophageal squamous cell carcinoma (RATIONALE-306): a global, randomised, placebo-co...

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Correlation between Lymphocyte-to-Monocyte Ratio (LMR), Neutrophil-to-Lymphocyte Ratio (NLR), Platelet-to-Lymphocyte Ratio (PLR) and Extramural Vascular Invasion (EMVI) in Locally Advanced Rectal Canc...

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Correlation between Lymphocyte-to-Monocyte Ratio (LMR), Neutrophil-to-Lymphocyte Ratio (NLR), Platelet-to-Lymphocyte Ratio (PLR) and Tumor-Infiltrating Lymphocytes (TILs) in Left-Sided Colorectal Canc...

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MABp1 as a novel antibody treatment for advanced colorectal cancer: a randomised, double-blind, placebo-controlled, phase 3 study

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Pembrolizumab in HER2-Positive Gastric Cancer

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Safety and efficacy of trifluridine/tipiracil in previously treated metastatic colorectal cancer: final results from the phase IIIb single-arm PRECONNECT study by duration of therapy

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Safety and efficacy of lenvatinib by starting dose based on body weight in patients with unresectable hepatocellular carcinoma in REFLECT

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Highlights from ASCO-GI 2021 from EORTC Gastrointestinal tract cancer group

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A Prospective Study on the Roles of the Lymphocyte-to-Monocyte Ratio (LMR), Neutrophil-to-Lymphocyte Ratio (NLR), and Platelet-to-Lymphocyte Ratio (PLR) in Patients with Locally Advanced Rectal Cancer

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Avelumab in patients with previously treated metastatic melanoma: phase 1b results from the JAVELIN Solid Tumor trial

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Nivolumab plus chemotherapy or ipilimumab versus chemotherapy in patients with advanced esophageal squamous cell carcinoma (CheckMate 648): 29‐month follow‐up from a randomized, open‐label, phase III...

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Avelumab (anti–PD-L1) as first-line switch-maintenance or second-line therapy in patients with advanced gastric or gastroesophageal junction cancer: phase 1b results from the JAVELIN Solid Tumor trial

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Growth Rate of Paragangliomas Related to Germline Mutations of the SDHx Genes

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ShapeGTB: the role of local DNA shape in prioritization of functional variants in human promoters with machine learning

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Integrating genomics, proteomics and bioinformatics in translational studies of molecular medicine

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