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Drug Resistance and the Role of Combination Chemotherapy in Improving Patient Outcomes
Author / Creator:Yardley, Denise A.
Publisher:Cairo, Egypt: Hindawi Limiteds
Journal title:International Journal of Breast Cancer, 2013-01, Vol.2013 (2013), p.26-40
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Adjuvant paclitaxel and trastuzumab for node-negative, HER2-positive breast cancer: final 10-year analysis of the open-label, single-arm, phase 2 APT trial
Author / Creator:Tolaney, Sara M, MD ; Tarantino, Paolo, MD ; Graham, Noah, MB ; Tayob, Nabihah, PhD ; Parè, Laia, PhD ; Villacampa, Guillermo ; Dang, Chau T, Prof ; Yardley, Denise A, MD ; Moy, Beverly, MD ; Marcom, P Kelly, MD ; Albain, Kathy S, Prof ; Rugo, Hope S, Prof ; Ellis, Matthew J, PhD ; Shapira, Iuliana, MD ; Wolff, Antonio C, Prof ; Carey, Lisa A, Prof ; Barroso-Sousa, Romualdo, MD ; Villagrasa, Patricia, PhD ; DeMeo, Michelle, BS ; DiLullo, Molly, BS ; Zanudo, Jorge Gomez Tejeda, PhD ; Weiss, Jakob, BS ; Wagle, Nikhil, MD ; Partridge, Ann H, Prof ; Waks, Adrienne G, MD ; Hudis, Clifford A, MD ; Krop, Ian E, MD ; Burstein, Harold J, Prof ; Prat, Aleix, Prof ; Winer, Eric P, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2023-03, Vol.24 (3), p.273-285
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Pictilisib for oestrogen receptor-positive, aromatase inhibitor-resistant, advanced or metastatic breast cancer (FERGI): a randomised, double-blind, placebo-controlled, phase 2 trial
Author / Creator:Krop, Ian E, Dr ; Mayer, Ingrid A, MD ; Ganju, Vinod, FRACP ; Dickler, Maura, MD ; Johnston, Stephen, MD ; Morales, Serafin, MD ; Yardley, Denise A, MD ; Melichar, Bohuslav, Prof ; Forero-Torres, Andres, MD ; Lee, Soo Chin, MRCP ; de Boer, Richard, FRACP ; Petrakova, Katarina, PhD ; Vallentin, Susanne, MD ; Perez, Edith A, MD ; Piccart, Martine, Prof ; Ellis, Matthew, Prof ; Winer, Eric, Prof ; Gendreau, Steven, PhD ; Derynck, Mika, MD ; Lackner, Mark, PhD ; Levy, Gallia, MD ; Qiu, Jiaheng, PhD ; He, Jing, MD ; Schmid, Peter, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2016-06, Vol.17 (6), p.811-821
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Neoadjuvant palbociclib plus either giredestrant or anastrozole in oestrogen receptor-positive, HER2-negative, early breast cancer (coopERA Breast Cancer): an open-label, randomised, controlled, phase...
Author / Creator:Hurvitz, Sara A, Prof ; Bardia, Aditya, MD MPH ; Quiroga, Vanesa, MD PhD ; Park, Yeon Hee, Prof ; Blancas, Isabel, MD PhD ; Alonso-Romero, José Luis, MD PhD ; Vasiliev, Aleksandr, MD ; Adamchuk, Hryhoriy, MD ; Salgado, Marcelo, MD PhD ; Yardley, Denise A, MD ; Berzoy, Oleksandr, MD ; Zamora-Auñón, Pilar, MD ; Chan, David, MD ; Spera, Gonzalo, MD MSc ; Xue, Cloris, PhD ; Ferreira, Erika, MEng ; Badovinac Crnjevic, Tanja, MD MSc ; Pérez-Moreno, Pablo Diego, MD ; López-Valverde, Vanesa, PhD ; Steinseifer, Jutta, MD PhD ; Fernando, Tharu M, PhD ; Moore, Heather M, PhD ; Fasching, Peter A, Prof
Publisher:London: Elsevier Ltd
Journal title:The lancet oncology, 2023-09, Vol.24 (9), p.1029-1041
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Etirinotecan pegol (NKTR-102) versus treatment of physician's choice in women with advanced breast cancer previously treated with an anthracycline, a taxane, and capecitabine (BEACON): a randomised, o...
Author / Creator:Perez, Edith A, Dr ; Awada, Ahmad, MD ; O'Shaughnessy, Joyce, MD ; Rugo, Hope S, MD ; Twelves, Chris, MD ; Im, Seock-Ah, MD ; Gómez-Pardo, Patricia, MD ; Schwartzberg, Lee S, MD ; Diéras, Veronique, MD ; Yardley, Denise A, MD ; Potter, David A, MD ; Mailliez, Audrey, MD ; Moreno-Aspitia, Alvaro, MD ; Ahn, Jin-Seok, MD ; Zhao, Carol, MS ; Hoch, Ute, PhD ; Tagliaferri, Mary, MD ; Hannah, Alison L, MD ; Cortes, Javier, MD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2015-11, Vol.16 (15), p.1556-1568
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Glembatumumab vedotin for patients with metastatic, gpNMB overexpressing, triple-negative breast cancer (“METRIC”): a randomized multicenter study
Author / Creator:Vahdat, Linda T. ; Schmid, Peter ; Forero-Torres, Andres ; Blackwell, Kimberly ; Telli, Melinda L. ; Melisko, Michelle ; Möbus, Volker ; Cortes, Javier ; Montero, Alberto J. ; Ma, Cynthia ; Nanda, Rita ; Wright, Gail S. ; He, Yi ; Hawthorne, Thomas ; Bagley, Rebecca G. ; Halim, Abdel-Baset ; Turner, Christopher D. ; Yardley, Denise A.
Publisher:London: Nature Publishing Group UK
Journal title:NPJ breast cancer, 2021-05, Vol.7 (1), p.57-57, Article 57
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Ribociclib plus Endocrine Therapy in Early Breast Cancer. Reply
Author / Creator:Slamon, Dennis ; Yardley, Denise A ; Hortobagyi, Gabriel
Publisher:United States
Journal title:The New England journal of medicine, 2024-06, Vol.390 (23), p.2221
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MONALEESA clinical program: a review of ribociclib use in different clinical settings
Author / Creator:Yardley, Denise A
Publisher:England: Future Medicine Ltd
Journal title:Future oncology (London, England), 2019-08, Vol.15 (23), p.2673-2686
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Adjuvant Pertuzumab and Trastuzumab in Early HER2-Positive Breast Cancer
Author / Creator:von Minckwitz, Gunter ; Procter, Marion ; de Azambuja, Evandro ; Zardavas, Dimitrios ; Benyunes, Mark ; Viale, Giuseppe ; Suter, Thomas ; Arahmani, Amal ; Rouchet, Nathalie ; Clark, Emma ; Knott, Adam ; Lang, Istvan ; Levy, Christelle ; Yardley, Denise A ; Bines, Jose ; Gelber, Richard D ; Piccart, Martine ; Baselga, Jose
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2017-07, Vol.377 (2), p.122-131
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ArticlesPeer ReviewedFull Text
Ribociclib plus Endocrine Therapy in Early Breast Cancer
Author / Creator:Slamon, Dennis ; Lipatov, Oleg ; Nowecki, Zbigniew ; McAndrew, Nicholas ; Kukielka-Budny, Bozena ; Stroyakovskiy, Daniil ; Yardley, Denise A. ; Huang, Chiun-Sheng ; Fasching, Peter A. ; Crown, John ; Bardia, Aditya ; Chia, Stephen ; Im, Seock-Ah ; Ruiz-Borrego, Manuel ; Loi, Sherene ; Xu, Binghe ; Hurvitz, Sara ; Barrios, Carlos ; Untch, Michael ; Moroose, Rebecca ; Visco, Frances ; Afenjar, Karen ; Fresco, Rodrigo ; Severin, Irene ; Ji, Yan ; Ghaznawi, Farhat ; Li, Zheng ; Zarate, Juan P. ; Chakravartty, Arunava ; Taran, Tetiana ; Hortobagyi, Gabriel
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2024-03, Vol.390 (12), p.1080-1091
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ArticlesPeer ReviewedFull Text
Adjuvant Paclitaxel and Trastuzumab for Node-Negative, HER2-Positive Breast Cancer
Author / Creator:Tolaney, Sara M ; Barry, William T ; Dang, Chau T ; Yardley, Denise A ; Moy, Beverly ; Marcom, P. Kelly ; Albain, Kathy S ; Rugo, Hope S ; Ellis, Matthew ; Shapira, Iuliana ; Wolff, Antonio C ; Carey, Lisa A ; Overmoyer, Beth A ; Partridge, Ann H ; Guo, Hao ; Hudis, Clifford A ; Krop, Ian E ; Burstein, Harold J ; Winer, Eric P
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2015-01, Vol.372 (2), p.134-141
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Safety and impact of dose reductions on efficacy in the randomised MONALEESA-2, -3 and -7 trials in hormone receptor-positive, HER2-negative advanced breast cancer
Author / Creator:Burris, Howard A. ; Chan, Arlene ; Bardia, Aditya ; Thaddeus Beck, J. ; Sohn, Joohyuk ; Neven, Patrick ; Tripathy, Debu ; Im, Seock-Ah ; Chia, Stephen ; Esteva, Francisco J. ; Hart, Lowell ; Zarate, Juan Pablo ; Ridolfi, Antonia ; Lorenc, Karen Rodriguez ; Yardley, Denise A.
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2021-08, Vol.125 (5), p.679-686
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HERMIONE: a randomized Phase 2 trial of MM-302 plus trastuzumab versus chemotherapy of physician’s choice plus trastuzumab in patients with previously treated, anthracycline-naïve, HER2-positive, loca...
Author / Creator:Miller, Kathy ; Cortes, Javier ; Hurvitz, Sara A. ; Krop, Ian E. ; Tripathy, Debu ; Verma, Sunil ; Riahi, Kaveh ; Reynolds, Joseph G. ; Wickham, Thomas J. ; Molnar, Istvan ; Yardley, Denise A.
Publisher:England: BioMed Central
Journal title:BMC cancer, 2016-06, Vol.16 (1), p.352, Article 352
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Second-line bevacizumab-containing therapy in patients with triple-negative breast cancer: subgroup analysis of the RIBBON-2 trial
Author / Creator:Brufsky, Adam ; Valero, Vicente ; Tiangco, Beatrice ; Dakhil, Shaker ; Brize, Arija ; Rugo, Hope S. ; Rivera, Ragene ; Duenne, Anja ; Bousfoul, Naima ; Yardley, Denise A.
Publisher:Boston: Springer US
Journal title:Breast cancer research and treatment, 2012-06, Vol.133 (3), p.1067-1075
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Treatment patterns and clinical outcomes for patients with de novo versus recurrent HER2-positive metastatic breast cancer
Author / Creator:Yardley, Denise A. ; Kaufman, Peter A. ; Brufsky, Adam ; Yood, Marianne Ulcickas ; Rugo, Hope ; Mayer, Musa ; Quah, Cheng ; Yoo, Bongin ; Tripathy, Debu
Publisher:Boston: Springer US
Journal title:Breast cancer research and treatment, 2014-06, Vol.145 (3), p.725-734
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Healthcare Resource Use and Expenditures among Metastatic Breast Cancer Patients Treated with HER2-Targeted Agents
Author / Creator:Meyer, Nicole ; Hao, Yanni ; Song, Xue ; Shi, Nianwen ; Johnson, William ; Willemann Rogerio, Jaqueline ; Yardley, Denise A.
Publisher:Cairo, Egypt: Hindawi Limiteds
Journal title:International Journal of Breast Cancer, 2014-01, Vol.2014 (2014), p.84-95
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HER2 heterogeneity and treatment response–associated profiles in HER2-positive breast cancer in the NCT02326974 clinical trial
Author / Creator:Li, Zheqi ; Metzger Filho, Otto ; Viale, Giuseppe ; dell’Orto, Patrizia ; Russo, Leila ; Goyette, Marie-Anne ; Kamat, Avni ; Yardley, Denise A. ; Gupta Abramson, Vandana ; Arteaga, Carlos L. ; Spring, Laura M. ; Chiotti, Kami ; Halsey, Carol ; Waks, Adrienne G. ; King, Tari A. ; Lester, Susan C. ; Bellon, Jennifer R. ; Winer, Eric P. ; Spellman, Paul T. ; Krop, Ian E. ; Polyak, Kornelia
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2024-04, Vol.134 (7), p.1-17
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Rationale and trial design of NATALEE: a Phase III trial of adjuvant ribociclib + endocrine therapy versus endocrine therapy alone in patients with HR+/HER2− early breast cancer
Author / Creator:Slamon, Dennis J. ; Fasching, Peter A. ; Hurvitz, Sara ; Chia, Stephen ; Crown, John ; Martín, Miguel ; Barrios, Carlos H. ; Bardia, Aditya ; Im, Seock-Ah ; Yardley, Denise A. ; Untch, Michael ; Huang, Chiun-Sheng ; Stroyakovskiy, Daniil ; Xu, Binghe ; Moroose, Rebecca L. ; Loi, Sherene ; Visco, Frances ; Bee-Munteanu, Valerie ; Afenjar, Karen ; Fresco, Rodrigo ; Taran, Tetiana ; Chakravartty, Arunava ; Zarate, Juan Pablo ; Lteif, Agnes ; Hortobagyi, Gabriel N.
Publisher:London, England: SAGE Publications
Journal title:Therapeutic advances in medical oncology, 2023-01, Vol.15, p.17588359231178125-17588359231178125
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A randomized, double-blind, phase 2 study of ruxolitinib or placebo in combination with capecitabine in patients with advanced HER2-negative breast cancer and elevated C-reactive protein, a marker of...
Author / Creator:O’Shaughnessy, Joyce ; DeMichele, Angela ; Ma, Cynthia X. ; Richards, Paul ; Yardley, Denise A. ; Wright, Gail Shaw ; Kalinsky, Kevin ; Steis, Ronald ; Diab, Sami ; Kennealey, Gerard ; Geschwindt, Ryan ; Jiang, Wei ; Rugo, Hope S.
Publisher:New York: Springer US
Journal title:Breast cancer research and treatment, 2018-08, Vol.170 (3), p.547-557
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Prolonged survival in patients with breast cancer and a history of brain metastases: results of a preplanned subgroup analysis from the randomized phase III BEACON trial
Author / Creator:Cortés, Javier ; Rugo, Hope S. ; Awada, Ahmad ; Twelves, Chris ; Perez, Edith A. ; Im, Seock–Ah ; Gómez-Pardo, Patricia ; Schwartzberg, Lee S. ; Diéras, Veronique ; Yardley, Denise A. ; Potter, David A. ; Mailliez, Audrey ; Moreno-Aspitia, Alvaro ; Ahn, Jin-Seok ; Zhao, Carol ; Hoch, Ute ; Tagliaferri, Mary ; Hannah, Alison L. ; O’Shaughnessy, Joyce
Publisher:New York: Springer US
Journal title:Breast cancer research and treatment, 2017-09, Vol.165 (2), p.329-341
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Drug Resistance and the Role of Combination Chemotherapy in Improving Patient Outcomes

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Adjuvant paclitaxel and trastuzumab for node-negative, HER2-positive breast cancer: final 10-year analysis of the open-label, single-arm, phase 2 APT trial

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Pictilisib for oestrogen receptor-positive, aromatase inhibitor-resistant, advanced or metastatic breast cancer (FERGI): a randomised, double-blind, placebo-controlled, phase 2 trial

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Neoadjuvant palbociclib plus either giredestrant or anastrozole in oestrogen receptor-positive, HER2-negative, early breast cancer (coopERA Breast Cancer): an open-label, randomised, controlled, phase...

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Etirinotecan pegol (NKTR-102) versus treatment of physician's choice in women with advanced breast cancer previously treated with an anthracycline, a taxane, and capecitabine (BEACON): a randomised, o...

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Glembatumumab vedotin for patients with metastatic, gpNMB overexpressing, triple-negative breast cancer (“METRIC”): a randomized multicenter study

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Ribociclib plus Endocrine Therapy in Early Breast Cancer. Reply

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MONALEESA clinical program: a review of ribociclib use in different clinical settings

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Adjuvant Pertuzumab and Trastuzumab in Early HER2-Positive Breast Cancer

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Ribociclib plus Endocrine Therapy in Early Breast Cancer

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Adjuvant Paclitaxel and Trastuzumab for Node-Negative, HER2-Positive Breast Cancer

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Safety and impact of dose reductions on efficacy in the randomised MONALEESA-2, -3 and -7 trials in hormone receptor-positive, HER2-negative advanced breast cancer

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HERMIONE: a randomized Phase 2 trial of MM-302 plus trastuzumab versus chemotherapy of physician’s choice plus trastuzumab in patients with previously treated, anthracycline-naïve, HER2-positive, loca...

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Second-line bevacizumab-containing therapy in patients with triple-negative breast cancer: subgroup analysis of the RIBBON-2 trial

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Treatment patterns and clinical outcomes for patients with de novo versus recurrent HER2-positive metastatic breast cancer

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Healthcare Resource Use and Expenditures among Metastatic Breast Cancer Patients Treated with HER2-Targeted Agents

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HER2 heterogeneity and treatment response–associated profiles in HER2-positive breast cancer in the NCT02326974 clinical trial

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Rationale and trial design of NATALEE: a Phase III trial of adjuvant ribociclib + endocrine therapy versus endocrine therapy alone in patients with HR+/HER2− early breast cancer

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A randomized, double-blind, phase 2 study of ruxolitinib or placebo in combination with capecitabine in patients with advanced HER2-negative breast cancer and elevated C-reactive protein, a marker of...

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Prolonged survival in patients with breast cancer and a history of brain metastases: results of a preplanned subgroup analysis from the randomized phase III BEACON trial

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