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ArticlesPeer ReviewedFull Text
Targeting Metalloenzymes: The "Achilles' Heel" of Viruses and Parasites
Author / Creator:Moianos, Dimitrios ; Prifti, Georgia-Myrto ; Makri, Maria ; Zoidis, Grigoris
Publisher:Switzerland: MDPI AG
Journal title:Pharmaceuticals (Basel, Switzerland), 2023-06, Vol.16 (6), p.901
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Recent Advances in Hepatitis B Treatment
Author / Creator:Prifti, Georgia-Myrto ; Moianos, Dimitrios ; Giannakopoulou, Erofili ; Pardali, Vasiliki ; Tavis, John E ; Zoidis, Grigoris
Publisher:Switzerland: MDPI AG
Journal title:Pharmaceuticals (Basel, Switzerland), 2021-05, Vol.14 (5), p.417
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N -Hydroxypiridinedione: A Privileged Heterocycle for Targeting the HBV RNase H
Author / Creator:Moianos, Dimitrios ; Makri, Maria ; Prifti, Georgia-Myrto ; Chiotellis, Aristeidis ; Pappas, Alexandros ; Woodson, Molly E ; Tajwar, Razia ; Tavis, John E ; Zoidis, Grigoris
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2024-06, Vol.29 (12), p.2942
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Novel Pyrazino[1,2- a ]indole-1,3(2 H ,4 H )-dione Derivatives Targeting the Replication of Flaviviridae Viruses: Structural and Mechanistic Insights
Author / Creator:Giannakopoulou, Erofili ; Akrani, Ifigeneia ; Mpekoulis, George ; Frakolaki, Efseveia ; Dimitriou, Marios ; Myrianthopoulos, Vassilios ; Vassilaki, Niki ; Zoidis, Grigoris
Publisher:Switzerland: MDPI AG
Journal title:Viruses, 2024-08, Vol.16 (8), p.1238
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Metal coordinating inhibitors of Rift Valley fever virus replication
Author / Creator:Geerling, Elizabeth ; Murphy, Valerie ; Mai, Maria C ; Stone, E. Taylor ; Casals, Andreu Gazquez ; Hassert, Mariah ; O'Dea, Austin T ; Cao, Feng ; Donlin, Maureen J ; Elagawany, Mohamed ; Elgendy, Bahaa ; Pardali, Vasiliki ; Giannakopoulou, Erofili ; Zoidis, Grigoris ; Schiavone, Daniel V ; Berkowitz, Alex J ; Agyemang, Nana B ; Murelli, Ryan P ; Tavis, John E ; Pinto, Amelia K ; Brien, James D
Publisher:San Francisco: Public Library of Science
Journal title:PloS one, 2022-09, Vol.17 (9), p.e0274266-e0274266
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1-Methyl-8-phenyl-1,3-diazaspiro[4.5]decane-2,4-dione
Author / Creator:Pardali, Vasiliki ; Katsamakas, Sotirios ; Giannakopoulou, Erofili ; Zoidis, Grigoris
Publisher:Basel: MDPI AG
Journal title:MolBank, 2021-06, Vol.2021 (2), p.M1228
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Design, Synthesis and 5-HT1A Binding Affinity of N-(3-(4-(2-Methoxyphenyl)piperazin-1-yl)propyl)tricyclo[3.3.1.13,7]decan-1-amine and N-(3-(4-(2-Methoxyphenyl)piperazin-1-yl)propyl)-3,5-dimethyl-tricy...
Author / Creator:Zoidis, Grigoris ; Loza, María Isabel ; Catto, Marco
Publisher:Basel: MDPI AG
Journal title:MolBank, 2022-03, Vol.2022 (1), p.M1353
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Novel Lipophilic Hydroxamates Based on Spirocarbocyclic Hydantoin Scaffolds with Potent Antiviral and Trypanocidal Activity
Author / Creator:Pardali, Vasiliki ; Giannakopoulou, Erofili ; Mpekoulis, George ; Tsopela, Vassilina ; Panos, Georgios ; Taylor, Martin C ; Kelly, John M ; Vassilaki, Niki ; Zoidis, Grigoris
Publisher:Switzerland: MDPI AG
Journal title:Pharmaceuticals (Basel, Switzerland), 2023-07, Vol.16 (7), p.1046
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ArticlesPeer ReviewedFull Text
Novel 6-Aminoquinazolinone Derivatives as Potential Cross GT1-4 HCV NS5B Inhibitors
Author / Creator:Nasr, Tamer ; Aboshanab, Ahmed M ; Mpekoulis, George ; Drakopoulos, Antonios ; Vassilaki, Niki ; Zoidis, Grigoris ; Abouzid, Khaled A M ; Zaghary, Wafaa
Publisher:Switzerland: MDPI AG
Journal title:Viruses, 2022-12, Vol.14 (12), p.2767
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ArticlesPeer ReviewedFull Text
Design and Synthesis of Novel Bis-Imidazolyl Phenyl Butadiyne Derivatives as HCV NS5A Inhibitors
Author / Creator:Hamdy, Jehad ; Emadeldin, Nouran ; Hamed, Mostafa M ; Frakolaki, Efseveia ; Katsamakas, Sotirios ; Vassilaki, Niki ; Zoidis, Grigoris ; Hirsch, Anna K H ; Abdel-Halim, Mohammad ; Abadi, Ashraf H
Publisher:Switzerland: MDPI AG
Journal title:Pharmaceuticals (Basel, Switzerland), 2022-05, Vol.15 (5), p.632
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ArticlesPeer ReviewedFull Text
Design and Synthesis of Novel Symmetric Fluorene-2,7-Diamine Derivatives as Potent Hepatitis C Virus Inhibitors
Author / Creator:Mousa, Mai H A ; Ahmed, Nermin S ; Schwedtmann, Kai ; Frakolaki, Efseveia ; Vassilaki, Niki ; Zoidis, Grigoris ; Weigand, Jan J ; Abadi, Ashraf H
Publisher:Switzerland: MDPI AG
Journal title:Pharmaceuticals (Basel, Switzerland), 2021-03, Vol.14 (4), p.292
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ArticlesPeer ReviewedFull Text
Development of Stilbenoid and Chalconoid Analogues as Potent Tyrosinase Modulators and Antioxidant Agents
Author / Creator:Vontzalidou, Argyro ; Dimitrakoudi, Sapfo-Maria ; Tsoukalas, Konstantinos ; Zoidis, Grigoris ; Chaita, Eliza ; Dina, Evanthia ; Cheimonidi, Christina ; Trougakos, Ioannis P. ; Lambrinidis, George ; Skaltsounis, Alexios-Leandros ; Mikros, Emmanuel ; Aligiannis, Nektarios
Publisher:Basel: MDPI AG
Journal title:Antioxidants, 2022-08, Vol.11 (8), p.1593
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ArticlesPeer ReviewedFull Text
Novel Pyrazino1,2-aindole-1,3(2H,4H)-dione Derivatives Targeting the Replication of Flaviviridae Viruses: Structural and Mechanistic Insights
Author / Creator:Giannakopoulou, Erofili ; Akrani, Ifigeneia ; Mpekoulis, George ; Frakolaki, Efseveia ; Dimitriou, Marios ; Myrianthopoulos, Vassilios ; Vassilaki, Niki ; Zoidis, Grigoris
Journal title:Viruses, 2024-08, Vol.16 (8)
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Are the 2-Isomers of the Drug Rimantadine Active Anti-Influenza a Agents?
Author / Creator:Zoidis, Grigoris ; Kolocouris, Nicolas ; Foscolos, George B ; Kolocouris, Antonios ; Fytas, George ; Karayannis, P ; Padalko, Elizaveta ; Neyts, Johan ; De Clercq, Erik
Publisher:London, England: SAGE Publications
Journal title:Antiviral chemistry & chemotherapy, 2003-06, Vol.14 (3), p.153-164
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ArticlesPeer ReviewedFull Text
1,2-Annulated Adamantane Heterocyclic Derivatives as Anti-Influenza A Virus Agents
Author / Creator:Pardali, Vasiliki ; Giannakopoulou, Erofili ; Konstantinidi, Athina ; Kolocouris, Antonios ; Zoidis, Grigoris
Publisher:Croatica Chemica Acta
Journal title:Croatica chemica acta, 2019-11, Vol.92 (2), p.1
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ArticlesPeer ReviewedFull Text
Discovery of bimodal hepatitis B virus ribonuclease H and capsid assembly inhibitors
Author / Creator:Bradley, Daniel P ; Valkner, Caleb J ; Li, Qilan ; Gasonoo, Makafui ; Meyers, Marvin J ; Prifti, Georgia-Myrto ; Moianos, Dimitrios ; Zoidis, Grigoris ; Zlotnick, Adam ; Tavis, John E
Publisher:United States
Journal title:PLoS pathogens, 2025-02, Vol.21 (2), p.e1012920
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ArticlesPeer ReviewedFull Text
1,2-Αnnulated Adamantane Heterocyclic Derivatives as Anti-Influenza Α Virus Agents
Author / Creator:Pardali, Vasiliki ; Giannakopoulou, Erofili ; Konstantinidi, Athina ; Kolocouris, Antonios ; Zoidis, Grigoris
Publisher:Zagreb: Croatica Chemica Acta, Croatian Chemical Society
Journal title:Croatica Chemica Acta, 2019, Vol.92 (2), p.211-228
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Novel 2,6-diketopiperazine-derived acetohydroxamic acids as promising anti- Trypanosoma brucei agents
Author / Creator:Fytas, George ; Zoidis, Grigoris ; Taylor, Martin C ; Kelly, John M ; Tsatsaroni, Alexandra ; Tsotinis, Andrew
Publisher:England
Journal title:Future medicinal chemistry, 2019-06, Vol.11 (11), p.1259-1266
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Reduction of the Risk of Hepatocellular Carcinoma over Time Using Direct-Acting Antivirals: A Propensity Score Analysis of a Real-Life Cohort (PITER HCV)
Author / Creator:Quaranta, Maria Giovanna ; Cavalletto, Luisa ; Russo, Francesco Paolo ; Calvaruso, Vincenza ; Ferrigno, Luigina ; Zanetto, Alberto ; Mattioli, Benedetta ; D'Ambrosio, Roberta ; Panetta, Valentina ; Brancaccio, Giuseppina ; Raimondo, Giovanni ; Brunetto, Maurizia Rossana ; Zignego, Anna Linda ; Coppola, Carmine ; Iannone, Andrea ; Biliotti, Elisa ; Rosselli Del Turco, Elena ; Massari, Marco ; Licata, Anna ; Barbaro, Francesco ; Persico, Marcello ; Morisco, Filomena ; Pompili, Maurizio ; Cerini, Federica ; Puoti, Massimo ; Santantonio, Teresa ; Craxì, Antonio ; Kondili, Loreta A ; Chemello, Liliana ; On Behalf Of Piter Collaborating Investigators
Publisher:Switzerland: MDPI AG
Journal title:Viruses, 2024-05, Vol.16 (5), p.682
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ReportsFull Text
Targeting Metalloenzymes: The “Achilles’ Heel” of Viruses and Parasites
Author / Creator:Moianos, Dimitrios ; Prifti, Georgia-Myrto ; Makri, Maria ; Zoidis, Grigoris
Publisher:MDPI AG
Journal title:Pharmaceuticals, 2023, Vol.16 (6)
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Showing 1 to 20 of 29 results

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Targeting Metalloenzymes: The "Achilles' Heel" of Viruses and Parasites

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Recent Advances in Hepatitis B Treatment

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N -Hydroxypiridinedione: A Privileged Heterocycle for Targeting the HBV RNase H

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Novel Pyrazino[1,2- a ]indole-1,3(2 H ,4 H )-dione Derivatives Targeting the Replication of Flaviviridae Viruses: Structural and Mechanistic Insights

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Metal coordinating inhibitors of Rift Valley fever virus replication

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1-Methyl-8-phenyl-1,3-diazaspiro[4.5]decane-2,4-dione

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Design, Synthesis and 5-HT1A Binding Affinity of N-(3-(4-(2-Methoxyphenyl)piperazin-1-yl)propyl)tricyclo[3.3.1.13,7]decan-1-amine and N-(3-(4-(2-Methoxyphenyl)piperazin-1-yl)propyl)-3,5-dimethyl-tricy...

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Novel Lipophilic Hydroxamates Based on Spirocarbocyclic Hydantoin Scaffolds with Potent Antiviral and Trypanocidal Activity

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Novel 6-Aminoquinazolinone Derivatives as Potential Cross GT1-4 HCV NS5B Inhibitors

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Design and Synthesis of Novel Bis-Imidazolyl Phenyl Butadiyne Derivatives as HCV NS5A Inhibitors

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Design and Synthesis of Novel Symmetric Fluorene-2,7-Diamine Derivatives as Potent Hepatitis C Virus Inhibitors

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Development of Stilbenoid and Chalconoid Analogues as Potent Tyrosinase Modulators and Antioxidant Agents

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Novel Pyrazino1,2-aindole-1,3(2H,4H)-dione Derivatives Targeting the Replication of Flaviviridae Viruses: Structural and Mechanistic Insights

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Are the 2-Isomers of the Drug Rimantadine Active Anti-Influenza a Agents?

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1,2-Annulated Adamantane Heterocyclic Derivatives as Anti-Influenza A Virus Agents

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Discovery of bimodal hepatitis B virus ribonuclease H and capsid assembly inhibitors

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1,2-Αnnulated Adamantane Heterocyclic Derivatives as Anti-Influenza Α Virus Agents

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Novel 2,6-diketopiperazine-derived acetohydroxamic acids as promising anti- Trypanosoma brucei agents

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Reduction of the Risk of Hepatocellular Carcinoma over Time Using Direct-Acting Antivirals: A Propensity Score Analysis of a Real-Life Cohort (PITER HCV)

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Targeting Metalloenzymes: The “Achilles’ Heel” of Viruses and Parasites

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