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ArticlesPeer ReviewedFull Text
Human islets expressing HNF1A variant have defective β cell transcriptional regulatory networks
Author / Creator:Haliyur, Rachana ; Tong, Xin ; Sanyoura, May ; Shrestha, Shristi ; Lindner, Jill ; Saunders, Diane C. ; Aramandla, Radhika ; Poffenberger, Greg ; Redick, Sambra D. ; Bottino, Rita ; Prasad, Nripesh ; Levy, Shawn E. ; Blind, Raymond D. ; Harlan, David M. ; Philipson, Louis H. ; Stein, Roland W. ; Brissova, Marcela ; Powers, Alvin C.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2019-01, Vol.129 (1), p.246-251
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HNF1A Mutations and Beta Cell Dysfunction in Diabetes
Author / Creator:Miyachi, Yasutaka ; Miyazawa, Takashi ; Ogawa, Yoshihiro
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2022-03, Vol.23 (6), p.3222
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Exosomal lncRNA HNF1A-AS1 affects cisplatin resistance in cervical cancer cells through regulating microRNA-34b/TUFT1 axis
Author / Creator:Luo, Xiaoqiong ; Wei, Jingxi ; Yang, Feng-Lian ; Pang, Xiao-Xia ; Shi, Feng ; Wei, Yu-Xia ; Liao, Bi-Yun ; Wang, Jun-Li
Publisher:England: BioMed Central
Journal title:Cancer cell international, 2019-12, Vol.19, p.323-323
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Long non-coding RNA HNF1A-AS1 regulates proliferation and migration in oesophageal adenocarcinoma cells
Author / Creator:Yang, Xue ; Song, Jee Hoon ; Cheng, Yulan ; Wu, Wenjing ; Bhagat, Tushar ; Yu, Yiting ; Abraham, John M ; Ibrahim, Sariat ; Ravich, William ; Roland, Bani Chander ; Khashab, Mouen ; Singh, Vikesh K ; Shin, Eun Ji ; Yang, Xiao ; Verma, Amit K ; Meltzer, Stephen J ; Mori, Yuriko
Publisher:England: BMJ Publishing Group LTD
Journal title:Gut, 2014-06, Vol.63 (6), p.881-890
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The HNF1α-regulated lncRNA HNF1A-AS1 reverses the malignancy of hepatocellular carcinoma by enhancing the phosphatase activity of SHP-1
Author / Creator:Ding, Chen-Hong ; Yin, Chuan ; Chen, Shi-Jie ; Wen, Liang-Zhi ; Ding, Kai ; Lei, Shu-Juan ; Liu, Jin-Pei ; Wang, Jian ; Chen, Kai-xian ; Jiang, Hua-liang ; Zhang, Xin ; Luo, Cheng ; Xie, Wei-Fen
Publisher:England: BioMed Central Ltd
Journal title:Molecular cancer, 2018-02, Vol.17 (1), p.63-63, Article 63
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HNF1A regulates oxaliplatin resistance in pancreatic cancer by targeting 53BP1
Author / Creator:Xia, Renpeng ; Hu, Chonghui ; Ye, Yuancheng ; Zhang, Xiang ; Li, Tingting ; He, Rihua ; Zheng, Shangyou ; Wen, Xiaofeng ; Chen, Rufu
Publisher:Athens: Spandidos Publications
Journal title:International journal of oncology, 2023-04, Vol.62 (4), p.1, Article 45
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Where to for precision treatment of HNF1A-MODY?
Author / Creator:Bonner, Caroline ; Saponaro, Chiara
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Diabetologia, 2022-11, Vol.65 (11), p.1825-1829
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In Silico Analysis Identified Putative Pathogenic Missense Single Nucleotide Polymorphisms (SNPs) in the Human HNF1A Gene
Author / Creator:Aldharee, Hitham ; Hamdan, Hamdan Z.
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2025-04, Vol.26 (8), p.3768
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Decreased GLUT2 and glucose uptake contribute to insulin secretion defects in MODY3/HNF1A hiPSC-derived mutant β cells
Author / Creator:Low, Blaise Su Jun ; Lim, Chang Siang ; Ding, Shirley Suet Lee ; Tan, Yaw Sing ; Ng, Natasha Hui Jin ; Krishnan, Vidhya Gomathi ; Ang, Su Fen ; Neo, Claire Wen Ying ; Verma, Chandra S. ; Hoon, Shawn ; Lim, Su Chi ; Tai, E. Shyong ; Teo, Adrian Kee Keong
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-05, Vol.12 (1), p.3133-3133, Article 3133
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The HASTER lncRNA promoter is a cis-acting transcriptional stabilizer of HNF1A
Author / Creator:Beucher, Anthony ; Miguel-Escalada, Irene ; Balboa, Diego ; De Vas, Matías G. ; Maestro, Miguel Angel ; Garcia-Hurtado, Javier ; Bernal, Aina ; Gonzalez-Franco, Roser ; Vargiu, Pierfrancesco ; Heyn, Holger ; Ravassard, Philippe ; Ortega, Sagrario ; Ferrer, Jorge
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2022-10, Vol.24 (10), p.1528-1540
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[Corrigendum] Knockdown of lncRNA HNF1A-AS1 inhibits oncogenic phenotypes in colorectal carcinoma
Author / Creator:Zhu, Wenyi ; Zhuang, Peipei ; Song, Wen ; Duan, Shiyu ; Xu, Qiong ; Peng, Man ; Zhou, Jun
Publisher:Greece: Spandidos Publications UK Ltd
Journal title:Molecular medicine reports, 2019-08, Vol.20 (2), p.2039-2040
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Variants influencing age at diagnosis of HNF1A-MODY
Author / Creator:Ludwig-Słomczyńska, Agnieszka H. ; Seweryn, Michał T. ; Radkowski, Piotr ; Kapusta, Przemysław ; Machlowska, Julita ; Pruhova, Stepanka ; Gasperikova, Daniela ; Bellanne-Chantelot, Christine ; Hattersley, Andrew ; Kandasamy, Balamurugan ; Letourneau-Freiberg, Lisa ; Philipson, Louis ; Doria, Alessandro ; Wołkow, Paweł P. ; Małecki, Maciej T. ; Klupa, Tomasz
Publisher:England: BioMed Central
Journal title:Molecular medicine (Cambridge, Mass.), 2022-09, Vol.28 (1), p.113-113, Article 113
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HNF4A and HNF1A exhibit tissue specific target gene regulation in pancreatic beta cells and hepatocytes
Author / Creator:Ng, Natasha Hui Jin ; Ghosh, Soumita ; Bok, Chek Mei ; Ching, Carmen ; Low, Blaise Su Jun ; Chen, Juin Ting ; Lim, Euodia ; Miserendino, María Clara ; Tan, Yaw Sing ; Hoon, Shawn ; Teo, Adrian Kee Keong
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-06, Vol.15 (1), p.4288-21, Article 4288
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Single cell multiomic analysis reveals diabetes-associated β-cell heterogeneity driven by HNF1A
Author / Creator:Weng, Chen ; Gu, Anniya ; Zhang, Shanshan ; Lu, Leina ; Ke, Luxin ; Gao, Peidong ; Liu, Xiaoxiao ; Wang, Yuntong ; Hu, Peinan ; Plummer, Dylan ; MacDonald, Elise ; Zhang, Saixian ; Xi, Jiajia ; Lai, Sisi ; Leskov, Konstantin ; Yuan, Kyle ; Jin, Fulai ; Li, Yan
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-09, Vol.14 (1), p.5400-5400, Article 5400
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HNF1A-MODY Mutations in Nuclear Localization Signal Impair HNF1A-Import Receptor KPNA6 Interactions
Author / Creator:Fareed, Fareed M. A. ; Korulu, Sirin ; Özbil, Mehmet ; Çapan, Özlem Yalçın
Publisher:New York: Springer US
Journal title:The Protein Journal, 2021-08, Vol.40 (4), p.512-521
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Novel insights into genetics and clinics of the HNF1A-MODY
Author / Creator:Valkovicova, Terezia ; Skopkova, Martina ; Stanik, Juraj ; Gasperikova, Daniela
Publisher:Germany: Sciendo
Journal title:Endocrine regulations (Bratislava), 2019-04, Vol.53 (2), p.110-134
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A multigenerational study on phenotypic consequences of the most common causal variant of HNF1A-MODY
Author / Creator:Kettunen, Jarno L. T. ; Rantala, Elina ; Dwivedi, Om P. ; Isomaa, Bo ; Sarelin, Leena ; Kokko, Paula ; Hakaste, Liisa ; Miettinen, Päivi J. ; Groop, Leif C. ; Tuomi, Tiinamaija
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Diabetologia, 2022-04, Vol.65 (4), p.632-643
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LncRNA-HNF1A-AS1 functions as a competing endogenous RNA to activate PI3K/AKT signalling pathway by sponging miR-30b-3p in gastric cancer
Author / Creator:Liu, Hai-Ting ; Ma, Ran-Ran ; Lv, Bei-Bei ; Zhang, Hui ; Shi, Duan-Bo ; Guo, Xiang-Yu ; Zhang, Guo-Hao ; Gao, Peng
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2020-06, Vol.122 (12), p.1825-1836
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The lncRNA HNF1A‐AS1 is a negative prognostic factor and promotes tumorigenesis in osteosarcoma
Author / Creator:Cai, Lijun ; Lv, Jinhan ; Zhang, Yinquan ; Li, Junhong ; Wang, Yinong ; Yang, Huilin
Publisher:England: John Wiley and Sons Inc
Journal title:Journal of cellular and molecular medicine, 2017-11, Vol.21 (11), p.2654-2662
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Aberrant methylation‑mediated decrease of lncRNA HNF1A‑AS1 contributes to malignant progression of laryngeal squamous cell carcinoma via EMT
Author / Creator:Shi, Yewen ; Zhang, Qingqing ; Xie, Meng ; Feng, Yani ; Ma, Sijing ; Yi, Chunxi ; Wang, Zihan ; Li, Yanju ; Liu, Xiaohong ; Liu, Haiqin ; Yang, Hui ; Yan, Yan ; Zhang, Yitong ; Ren, Xiaoyong ; Luo, Huanan
Publisher:Greece: Spandidos Publications
Journal title:Oncology reports, 2020-12, Vol.44 (6), p.2503-2516
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Human islets expressing HNF1A variant have defective β cell transcriptional regulatory networks

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HNF1A Mutations and Beta Cell Dysfunction in Diabetes

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Exosomal lncRNA HNF1A-AS1 affects cisplatin resistance in cervical cancer cells through regulating microRNA-34b/TUFT1 axis

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Long non-coding RNA HNF1A-AS1 regulates proliferation and migration in oesophageal adenocarcinoma cells

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The HNF1α-regulated lncRNA HNF1A-AS1 reverses the malignancy of hepatocellular carcinoma by enhancing the phosphatase activity of SHP-1

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HNF1A regulates oxaliplatin resistance in pancreatic cancer by targeting 53BP1

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Where to for precision treatment of HNF1A-MODY?

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In Silico Analysis Identified Putative Pathogenic Missense Single Nucleotide Polymorphisms (SNPs) in the Human HNF1A Gene

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Decreased GLUT2 and glucose uptake contribute to insulin secretion defects in MODY3/HNF1A hiPSC-derived mutant β cells

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The HASTER lncRNA promoter is a cis-acting transcriptional stabilizer of HNF1A

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[Corrigendum] Knockdown of lncRNA HNF1A-AS1 inhibits oncogenic phenotypes in colorectal carcinoma

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Variants influencing age at diagnosis of HNF1A-MODY

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HNF4A and HNF1A exhibit tissue specific target gene regulation in pancreatic beta cells and hepatocytes

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Single cell multiomic analysis reveals diabetes-associated β-cell heterogeneity driven by HNF1A

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HNF1A-MODY Mutations in Nuclear Localization Signal Impair HNF1A-Import Receptor KPNA6 Interactions

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Novel insights into genetics and clinics of the HNF1A-MODY

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A multigenerational study on phenotypic consequences of the most common causal variant of HNF1A-MODY

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LncRNA-HNF1A-AS1 functions as a competing endogenous RNA to activate PI3K/AKT signalling pathway by sponging miR-30b-3p in gastric cancer

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The lncRNA HNF1A‐AS1 is a negative prognostic factor and promotes tumorigenesis in osteosarcoma

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Aberrant methylation‑mediated decrease of lncRNA HNF1A‑AS1 contributes to malignant progression of laryngeal squamous cell carcinoma via EMT

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