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Host-induced gene silencing of cytochrome P450 lanosterol C14α-demethylase–encoding genes confers strong resistance to Fusarium species
Author / Creator:Koch, Aline ; Kumar, Neelendra ; Weber, Lennart ; Keller, Harald ; Imani, Jafargholi ; Kogel, Karl-Heinz
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2013-11, Vol.110 (48), p.19324-19329
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Lanosterol reverses protein aggregation in cataracts
Author / Creator:Zhao, Ling ; Chen, Xiang-Jun ; Zhu, Jie ; Xi, Yi-Bo ; Yang, Xu ; Hu, Li-Dan ; Ouyang, Hong ; Patel, Sherrina H. ; Jin, Xin ; Lin, Danni ; Wu, Frances ; Flagg, Ken ; Cai, Huimin ; Li, Gen ; Cao, Guiqun ; Lin, Ying ; Chen, Daniel ; Wen, Cindy ; Chung, Christopher ; Wang, Yandong ; Qiu, Austin ; Yeh, Emily ; Wang, Wenqiu ; Hu, Xun ; Grob, Seanna ; Abagyan, Ruben ; Su, Zhiguang ; Tjondro, Harry Christianto ; Zhao, Xi-Juan ; Luo, Hongrong ; Hou, Rui ; Jefferson, J. ; Perry, P. ; Gao, Weiwei ; Kozak, Igor ; Granet, David ; Li, Yingrui ; Sun, Xiaodong ; Wang, Jun ; Zhang, Liangfang ; Liu, Yizhi ; Yan, Yong-Bin ; Zhang, Kang
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2015-07, Vol.523 (7562), p.607-611
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Target identification reveals lanosterol synthase as a vulnerability in glioma
Author / Creator:Phillips, Richard E. ; Yang, Yanhong ; Smith, Ryan C. ; Thompson, Bonne M. ; Yamasaki, Tomoko ; Soto-Feliciano, Yadira M. ; Funato, Kosuke ; Liang, Yupu ; Garcia-Bermudez, Javier ; Wang, Xiaoshi ; Garcia, Benjamin A. ; Yamasaki, Kazuhiko ; McDonald, Jeffrey G. ; Birsoy, Kivanç ; Tabar, Viviane ; Allis, C. David
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2019-04, Vol.116 (16), p.7957-7962
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Human Lanosterol 14-Alpha Demethylase (CYP51A1) Is a Putative Target for Natural Flavonoid Luteolin 7,3′-Disulfate
Author / Creator:Kaluzhskiy, Leonid ; Ershov, Pavel ; Yablokov, Evgeniy ; Shkel, Tatsiana ; Grabovec, Irina ; Mezentsev, Yuri ; Gnedenko, Oksana ; Usanov, Sergey ; Shabunya, Polina ; Fatykhava, Sviatlana ; Popov, Alexander ; Artyukov, Aleksandr ; Styshova, Olga ; Gilep, Andrei ; Strushkevich, Natallia ; Ivanov, Alexis
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2021-04, Vol.26 (8), p.2237
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Hydroxyzine Effects on Post-Lanosterol Biosynthesis in Smith–Lemli–Opitz Syndrome (SLOS) Models
Author / Creator:Korade, Zeljka ; Anderson, Allison C. ; Balog, Marta ; Tallman, Keri A. ; Porter, Ned A. ; Mirnics, Karoly
Publisher:Switzerland: MDPI AG
Journal title:Biomolecules (Basel, Switzerland), 2025-04, Vol.15 (4), p.562
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Structural and Functional Elucidation of Yeast Lanosterol 14α-Demethylase in Complex with Agrochemical Antifungals
Author / Creator:Tyndall, Joel D. A. ; Sabherwal, Manya ; Sagatova, Alia A. ; Keniya, Mikhail V. ; Negroni, Jacopo ; Wilson, Rajni K. ; Woods, Matthew A. ; Tietjen, Klaus ; Monk, Brian C.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-12, Vol.11 (12), p.e0167485-e0167485
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Biosynthesis of lanosterol in Escherichia coli Biosynthesis of lanosterol in Escherichia coli
Author / Creator:Wenjie Sun ; Yun Chen ; Syed Bilal Shah ; Yanfen Bai ; Zaigao Tan
Publisher:KeAi Communications Co., Ltd
Journal title:Synthetic and systems biotechnology, 2025-09, Vol.10 (3), p.993-1001
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Biosynthesis of lanosterol in Escherichia coli
Author / Creator:Sun, Wenjie ; Chen, Yun ; Shah, Syed Bilal ; Bai, Yanfen ; Tan, Zaigao
Journal title:Synthetic and systems biotechnology, 2025-09, Vol.10 (3), p.993-1001
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Development of Procathepsin L (pCTS-L)-Inhibiting Lanosterol-Carrying Liposome Nanoparticles to Treat Lethal Sepsis
Author / Creator:Chen, Weiqiang ; Zhu, Cassie Shu ; Qiang, Xiaoling ; Chen, Shujin ; Li, Jianhua ; Wang, Ping ; Tracey, Kevin J. ; Wang, Haichao
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2023-05, Vol.24 (10), p.8649
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Bone marrow stromal cells dictate lanosterol biosynthesis and ferroptosis of multiple myeloma
Author / Creator:Jiang, Hongmei ; Wang, Lijuan ; Zhang, Qiguo ; Wang, Sheng ; Jia, Linchuang ; Cheng, Hao ; Wang, Jingya ; Li, Xin ; Xie, Ying ; Wang, Yixuan ; Hu, Meilin ; Guo, Jing ; Li, Qian ; Peng, Ziyi ; Wang, Mengqi ; Xie, Yangyang ; Li, Tiantian ; Wang, Yafei ; Geng, Bill D. ; Swaminathan, Sundararaman ; Bergsagel, P. Leif ; Liu, Zhiqiang
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2024-05, Vol.43 (21), p.1644-1653
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Failure of Oxysterols Such as Lanosterol to Restore Lens Clarity from Cataracts
Author / Creator:Daszynski, Damian M. ; Santhoshkumar, Puttur ; Phadte, Ashutosh S. ; Sharma, K. Krishna ; Zhong, Haizhen A. ; Lou, Marjorie F. ; Kador, Peter F.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-06, Vol.9 (1), p.8459, Article 8459
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Effect of lanosterol on human cataract nucleus
Author / Creator:Shanmugam, P ; Barigali, Aditya ; Kadaskar, Jayant ; Borgohain, Sandip ; Mishra, Divaynsh ; Ramanjulu, Rajesh ; Minija, C
Publisher:India: Wolters Kluwer - Medknow Publications
Journal title:Indian journal of ophthalmology, 2015-12, Vol.63 (12), p.888-890
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Design, Synthesis and Antifungal Activity Evaluation of New Thiazolin-4-ones as Potential Lanosterol 14α-Demethylase Inhibitors
Author / Creator:Stana, Anca ; Vodnar, Dan ; Tamaian, Radu ; Pîrnău, Adrian ; Vlase, Laurian ; Ionuț, Ioana ; Oniga, Ovidiu ; Tiperciuc, Brînduşa
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2017-01, Vol.18 (1), p.177
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Biallelic pathogenic variants in the lanosterol synthase gene LSS involved in the cholesterol biosynthesis cause alopecia with intellectual disability, a rare recessive neuroectodermal syndrome
Author / Creator:Besnard, Thomas ; Sloboda, Natacha ; Goldenberg, Alice ; Küry, Sébastien ; Cogné, Benjamin ; Breheret, Flora ; Trochu, Eva ; Conrad, Solène ; Vincent, Marie ; Deb, Wallid ; Balguerie, Xavier ; Barbarot, Sébastien ; Baujat, Geneviève ; Ben-Omran, Tawfeg ; Bursztejn, Anne-Claire ; Carmignac, Virginie ; Datta, Alexandre N. ; Delignières, Aline ; Faivre, Laurence ; Gardie, Betty ; Guéant, Jean-Louis ; Kuentz, Paul ; Lenglet, Marion ; Nassogne, Marie-Cécile ; Ramaekers, Vincent ; Schnur, Rhonda E. ; Si, Yue ; Torti, Erin ; Thevenon, Julien ; Vabres, Pierre ; Van Maldergem, Lionel ; Wand, Dorothea ; Wiedemann, Arnaud ; Cariou, Bertrand ; Redon, Richard ; Lamazière, Antonin ; Bézieau, Stéphane ; Feillet, Francois ; Isidor, Bertrand
Publisher:New York: Elsevier Inc
Journal title:Genetics in medicine, 2019-09, Vol.21 (9), p.2025-2035
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Triazole resistance mediated by mutations of a conserved active site tyrosine in fungal lanosterol 14α-demethylase
Author / Creator:Sagatova, Alia A. ; Keniya, Mikhail V. ; Wilson, Rajni K. ; Sabherwal, Manya ; Tyndall, Joel D. A. ; Monk, Brian C.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-05, Vol.6 (1), p.26213-26213, Article 26213
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Lanosterol Suppresses the Aggregation and Cytotoxicity of Misfolded Proteins Linked with Neurodegenerative Diseases
Author / Creator:Upadhyay, Arun ; Amanullah, Ayeman ; Mishra, Ribhav ; Kumar, Amit ; Mishra, Amit
Publisher:New York: Springer US
Journal title:Molecular neurobiology, 2018-02, Vol.55 (2), p.1169-1182
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Dual biosynthetic pathways to phytosterol via cycloartenol and lanosterol in Arabidopsis
Author / Creator:Ohyama, Kiyoshi ; Suzuki, Masashi ; Kikuchi, Jun ; Saito, Kazuki ; Muranaka, Toshiya
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2009-01, Vol.106 (3), p.725-730
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Intrinsic short-tailed azole resistance in mucormycetes is due to an evolutionary conserved aminoacid substitution of the lanosterol 14α-demethylase
Author / Creator:Caramalho, Rita ; Tyndall, Joel D. A. ; Monk, Brian C. ; Larentis, Thomas ; Lass-Flörl, Cornelia ; Lackner, Michaela
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-11, Vol.7 (1), p.15898-10, Article 15898
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Increased lanosterol turnover: a metabolic burden for daunorubicin-resistant leukemia cells
Author / Creator:Stäubert, Claudia ; Krakowsky, Rosanna ; Bhuiyan, Hasanuzzaman ; Witek, Barbara ; Lindahl, Anna ; Broom, Oliver ; Nordström, Anders
Publisher:New York: Springer US
Journal title:Medical oncology (Northwood, London, England), 2016-01, Vol.33 (1), p.6-6, Article 6
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An Erg11 lanosterol 14-α-demethylase-Arv1 complex is required for Candida albicans virulence
Author / Creator:Villasmil, Michelle L. ; Barbosa, Antonio Daniel ; Cunningham, Jessie Lee ; Siniossoglou, Symeon ; Nickels, Joseph T.
Publisher:San Francisco: Public Library of Science
Journal title:PloS one, 2020-07, Vol.15 (7), p.e0235746-e0235746
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Showing 1 to 20 of 950 results

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Host-induced gene silencing of cytochrome P450 lanosterol C14α-demethylase–encoding genes confers strong resistance to Fusarium species

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Lanosterol reverses protein aggregation in cataracts

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Target identification reveals lanosterol synthase as a vulnerability in glioma

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Human Lanosterol 14-Alpha Demethylase (CYP51A1) Is a Putative Target for Natural Flavonoid Luteolin 7,3′-Disulfate

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Hydroxyzine Effects on Post-Lanosterol Biosynthesis in Smith–Lemli–Opitz Syndrome (SLOS) Models

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Structural and Functional Elucidation of Yeast Lanosterol 14α-Demethylase in Complex with Agrochemical Antifungals

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Biosynthesis of lanosterol in Escherichia coli Biosynthesis of lanosterol in Escherichia coli

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Biosynthesis of lanosterol in Escherichia coli

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Development of Procathepsin L (pCTS-L)-Inhibiting Lanosterol-Carrying Liposome Nanoparticles to Treat Lethal Sepsis

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Bone marrow stromal cells dictate lanosterol biosynthesis and ferroptosis of multiple myeloma

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Failure of Oxysterols Such as Lanosterol to Restore Lens Clarity from Cataracts

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Effect of lanosterol on human cataract nucleus

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Design, Synthesis and Antifungal Activity Evaluation of New Thiazolin-4-ones as Potential Lanosterol 14α-Demethylase Inhibitors

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Biallelic pathogenic variants in the lanosterol synthase gene LSS involved in the cholesterol biosynthesis cause alopecia with intellectual disability, a rare recessive neuroectodermal syndrome

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Triazole resistance mediated by mutations of a conserved active site tyrosine in fungal lanosterol 14α-demethylase

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Lanosterol Suppresses the Aggregation and Cytotoxicity of Misfolded Proteins Linked with Neurodegenerative Diseases

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Dual biosynthetic pathways to phytosterol via cycloartenol and lanosterol in Arabidopsis

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Intrinsic short-tailed azole resistance in mucormycetes is due to an evolutionary conserved aminoacid substitution of the lanosterol 14α-demethylase

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Increased lanosterol turnover: a metabolic burden for daunorubicin-resistant leukemia cells

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An Erg11 lanosterol 14-α-demethylase-Arv1 complex is required for Candida albicans virulence

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