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Globally prevalent PfMDR1 mutations modulate Plasmodium falciparum susceptibility to artemisinin-based combination therapies
Author / Creator:Veiga, M. Isabel ; Dhingra, Satish K. ; Henrich, Philipp P. ; Straimer, Judith ; Gnädig, Nina ; Uhlemann, Anne-Catrin ; Martin, Rowena E. ; Lehane, Adele M. ; Fidock, David A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2016-05, Vol.7 (1), p.11553-12, Article 11553
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Prevalence of pfk13 and pfmdr1 polymorphisms in Bounkiling, Southern Senegal
Author / Creator:Ahouidi, Ambroise ; Oliveira, Rafael ; Lobo, Lis ; Diedhiou, Cyrille ; Mboup, Souleymane ; Nogueira, Fatima
Publisher:United States: Public Library of Science
Journal title:PloS one, 2021-03, Vol.16 (3), p.e0249357
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Mechanistic basis for multidrug resistance and collateral drug sensitivity conferred to the malaria parasite by polymorphisms in PfMDR1 and PfCRT
Author / Creator:Shafik, Sarah Heckmatt ; Richards, Sashika Natasha ; Corry, Ben ; Martin, Rowena Elizabeth
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2022-05, Vol.20 (5), p.e3001616-e3001616
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PfMDR1 Transport Rates Assessed in Intact Isolated Plasmodium falciparum Digestive Vacuoles Reflect Functional Drug Resistance Relationship with pfmdr1 Mutations
Author / Creator:Simon, Nina ; Voigtländer, Cornelia ; Kappes, Barbara ; Rohrbach, Petra ; Friedrich, Oliver
Publisher:Switzerland: MDPI AG
Journal title:Pharmaceuticals (Basel, Switzerland), 2022-02, Vol.15 (2), p.202
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Directional Selection at the pfmdr1, pfcrt, pfubp1, and pfap2mu Loci of Plasmodium falciparum in Kenyan Children Treated With ACT
Author / Creator:Henriques, Gisela ; Hallett, Rachel L. ; Beshir, Khalid B. ; Gadalla, Nahla B. ; Johnson, Rachel E. ; Burrow, Rebekah ; van Schalkwyk, Donelly A. ; Sawa, Patrick ; Omar, Sabah A. ; Clark, Taane G. ; Bousema, Teun ; Sutherland, Colin J.
Publisher:Oxford: Oxford University Press
Journal title:The Journal of infectious diseases, 2014-12, Vol.210 (12), p.2001-2008
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Polymorphisms in the Pfcrt, Pfmdr1, and Pfk13 genes of Plasmodium falciparum isolates from southern Brazzaville, Republic of Congo
Author / Creator:Baina, Marcel Tapsou ; Djontu, Jean Claude ; Mbama Ntabi, Jacques Dollon ; Mfoutou Mapanguy, Claujens Chastel ; Lissom, Abel ; Vouvoungui, Christevy Jeannhey ; Boumpoutou, Reauchelvy Kamal ; Mouanga, Alain Maxime ; Nguimbi, Etienne ; Ntoumi, Francine
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-11, Vol.14 (1), p.27988-11, Article 27988
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In Vivo Selection of Plasmodium falciparum pfmdr1 86N Coding Alleles by Artemether-Lumefantrine (Coartem)
Author / Creator:Sisowath, Christin ; Strömberg, Johan ; Mårtensson, Andreas ; Msellem, Mwinyi ; Obondo, Christine ; Björkman, Anders ; Gil, José P.
Publisher:Chicago, IL: The University of Chicago Press
Journal title:The Journal of infectious diseases, 2005-03, Vol.191 (6), p.1014-1017
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Analysis of Plasmodium falciparum Pfcrt and Pfmdr1 genes in parasite isolates from asymptomatic individuals in Southeast Nigeria 11 years after withdrawal of chloroquine
Author / Creator:Ikegbunam, Moses N. ; Nkonganyi, Charles N. ; Thomas, Bolaji N. ; Esimone, Charles O. ; Velavan, Thirumalaisamy P. ; Ojurongbe, Olusola
Publisher:England: BioMed Central Ltd
Journal title:Malaria journal, 2019-10, Vol.18 (1), p.343-7, Article 343
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A novel 4-aminoquinoline chemotype with multistage antimalarial activity and lack of cross-resistance with PfCRT and PfMDR1 mutants
Author / Creator:Ferreira, Letícia Tiburcio ; Cassiano, Gustavo Capatti ; Alvarez, Luis Carlos Salazar ; Okombo, John ; Calit, Juliana ; Fontinha, Diana ; Gil-Iturbe, Eva ; Coyle, Rachael ; Andrade, Carolina Horta ; Sunnerhagen, Per ; Bargieri, Daniel Youssef ; Prudêncio, Miguel ; Quick, Matthias ; Cravo, Pedro V. ; Lee, Marcus C. S. ; Fidock, David A. ; Costa, Fabio Trindade Maranhão
Publisher:United States: PLoS
Journal title:PLoS pathogens, 2024-10, Vol.20 (10), p.e1012627
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The Role of Pfmdr1 and Pfcrt in Changing Chloroquine, Amodiaquine, Mefloquine and Lumefantrine Susceptibility in Western-Kenya P. falciparum Samples during 2008–2011
Author / Creator:Eyase, Fredrick L. ; Akala, Hoseah M. ; Ingasia, Luiser ; Cheruiyot, Agnes ; Omondi, Angela ; Okudo, Charles ; Juma, Dennis ; Yeda, Redemptah ; Andagalu, Ben ; Wanja, Elizabeth ; Kamau, Edwin ; Schnabel, David ; Bulimo, Wallace ; Waters, Norman C. ; Walsh, Douglas S. ; Johnson, Jacob D.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-05, Vol.8 (5), p.e64299
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Increased pfmdr1 gene copy number and the decline in pfcrt and pfmdr1 resistance alleles in Ghanaian Plasmodium falciparum isolates after the change of anti-malarial drug treatment policy
Author / Creator:Duah, Nancy O ; Matrevi, Sena A ; de Souza, Dziedzom K ; Binnah, Daniel D ; Tamakloe, Mary M ; Opoku, Vera S ; Onwona, Christiana O ; Narh, Charles A ; Quashie, Neils B ; Abuaku, Benjamin ; Duplessis, Christopher ; Kronmann, Karl C ; Koram, Kwadwo A
Publisher:England: BioMed Central Ltd
Journal title:Malaria journal, 2013-10, Vol.12 (1), p.377-377, Article 377
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Polymorphism analysis of pfmdr1 gene in Plasmodium falciparum isolates 11 years post-adoption of artemisinin-based combination therapy in Saudi Arabia
Author / Creator:Al-Mekhlafi, Hesham M. ; Madkhali, Aymen M. ; Abdulhaq, Ahmed A. ; Atroosh, Wahib M. ; Ghzwani, Ahmad Hassn ; Zain, Khalid Ammash ; Ghailan, Khalid Y. ; Hamali, Hassan A. ; Mobarki, Abdullah A. ; Alharazi, Talal H. ; Eisa, Zaki M. ; Lau, Yee-Ling
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2022-01, Vol.12 (1), p.517-13, Article 517
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Assessment of Plasmodium falciparum anti-malarial drug resistance markers in pfcrt and pfmdr1 genes in isolates from Honduras and Nicaragua, 2018–2021
Author / Creator:Fontecha, Gustavo ; Pinto, Alejandra ; Archaga, Osman ; Betancourth, Sergio ; Escober, Lenin ; Henríquez, Jessica ; Valdivia, Hugo O. ; Montoya, Alberto ; Mejía, Rosa Elena
Publisher:England: BioMed Central Ltd
Journal title:Malaria journal, 2021-12, Vol.20 (1), p.465-465, Article 465
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Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number
Author / Creator:Price, Ric N ; Uhlemann, Anne-Catrin ; Brockman, Alan ; McGready, Rose ; Ashley, Elizabeth ; Phaipun, Lucy ; Patel, Rina ; Laing, Kenneth ; Looareesuwan, Sornchai ; White, Nicholas J ; Nosten, François ; Krishna, Sanjeev
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2004-07, Vol.364 (9432), p.438-447
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Low prevalence of copy number variation in pfmdr1 and pfpm2 in Plasmodium falciparum isolates from southern Angola
Author / Creator:Duarte, Denise ; Manuel, Francisco ; Dias, Ana ; Sacato, Esmeralda ; Taleingue, Elsa ; Daniel, Elsa ; Simão, Francisco ; Varandas, Luis ; Antunes, Maria Lina ; Nogueira, Fatima
Publisher:England: BioMed Central Ltd
Journal title:Malaria journal, 2025-01, Vol.24 (1), p.5-8, Article 5
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Plasmodium falciparum Drug Resistance Phenotype as Assessed by Patient Antimalarial Drug Levels and Its Association With pfmdr1 Polymorphisms
Author / Creator:Malmberg, Maja ; Ferreira, Pedro E. ; Tarning, Joel ; Ursing, Johan ; Ngasala, Billy ; Björkman, Anders ; Mårtensson, Andreas ; Gil, José P.
Publisher:United States: Oxford University Press
Journal title:The Journal of infectious diseases, 2013-03, Vol.207 (5), p.842-847
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Asymptomatic malaria infections and Pfmdr1 mutations in an endemic area of Nigeria
Author / Creator:Dokunmu, Titilope M. ; Adjekukor, Cynthia U. ; Yakubu, Omolara F. ; Bello, Adetutu O. ; Adekoya, Jarat O. ; Akinola, Olugbenga ; Amoo, Emmanuel O. ; Adebayo, Abiodun H.
Publisher:England: BioMed Central Ltd
Journal title:Malaria journal, 2019-06, Vol.18 (1), p.218-218, Article 218
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Antimalarial drug resistance in the Central and Adamawa regions of Cameroon: Prevalence of mutations in P. falciparum crt, Pfmdr1, Pfdhfr and Pfdhps genes
Author / Creator:Tuedom, Aline Gaelle Bouopda ; Sarah-Matio, Elangwe Milo ; Moukoko, Carole Else Eboumbou ; Feufack-Donfack, Brice Lionel ; Maffo, Christelle Ngou ; Bayibeki, Albert Ngano ; Awono-Ambene, Hermann Parfait ; Ayong, Lawrence ; Berry, Antoine ; Abate, Luc ; Morlais, Isabelle ; Nsango, Sandrine Eveline
Publisher:United States: Public Library of Science
Journal title:PloS one, 2021-08, Vol.16 (8), p.e0256343
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Assessment of Plasmodium falciparum PfMDR1 transport rates using Fluo‐4
Author / Creator:Friedrich, O. ; Reiling, S.J. ; Wunderlich, J. ; Rohrbach, P.
Publisher:England: Blackwell Publishing Ltd
Journal title:Journal of cellular and molecular medicine, 2014-09, Vol.18 (9), p.1851-1862
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Assessment of Plasmodium falciparum anti-malarial drug resistance markers in pfk13-propeller, pfcrt and pfmdr1 genes in isolates from treatment failure patients in Democratic Republic of Congo, 2018–2...
Author / Creator:Yobi, Doudou M. ; Kayiba, Nadine K. ; Mvumbi, Dieudonné M. ; Boreux, Raphael ; Kabututu, Pius Z. ; Situakibanza, Hippolyte N. T. ; Umesumbu, Solange E. ; De Mol, Patrick ; Speybroeck, Niko ; Mvumbi, Georges L. ; Hayette, Marie-Pierre
Publisher:England: BioMed Central Ltd
Journal title:Malaria journal, 2021-03, Vol.20 (1), p.144-144, Article 144
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Globally prevalent PfMDR1 mutations modulate Plasmodium falciparum susceptibility to artemisinin-based combination therapies

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Prevalence of pfk13 and pfmdr1 polymorphisms in Bounkiling, Southern Senegal

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Mechanistic basis for multidrug resistance and collateral drug sensitivity conferred to the malaria parasite by polymorphisms in PfMDR1 and PfCRT

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PfMDR1 Transport Rates Assessed in Intact Isolated Plasmodium falciparum Digestive Vacuoles Reflect Functional Drug Resistance Relationship with pfmdr1 Mutations

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Directional Selection at the pfmdr1, pfcrt, pfubp1, and pfap2mu Loci of Plasmodium falciparum in Kenyan Children Treated With ACT

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Polymorphisms in the Pfcrt, Pfmdr1, and Pfk13 genes of Plasmodium falciparum isolates from southern Brazzaville, Republic of Congo

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In Vivo Selection of Plasmodium falciparum pfmdr1 86N Coding Alleles by Artemether-Lumefantrine (Coartem)

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Analysis of Plasmodium falciparum Pfcrt and Pfmdr1 genes in parasite isolates from asymptomatic individuals in Southeast Nigeria 11 years after withdrawal of chloroquine

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A novel 4-aminoquinoline chemotype with multistage antimalarial activity and lack of cross-resistance with PfCRT and PfMDR1 mutants

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The Role of Pfmdr1 and Pfcrt in Changing Chloroquine, Amodiaquine, Mefloquine and Lumefantrine Susceptibility in Western-Kenya P. falciparum Samples during 2008–2011

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Increased pfmdr1 gene copy number and the decline in pfcrt and pfmdr1 resistance alleles in Ghanaian Plasmodium falciparum isolates after the change of anti-malarial drug treatment policy

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Polymorphism analysis of pfmdr1 gene in Plasmodium falciparum isolates 11 years post-adoption of artemisinin-based combination therapy in Saudi Arabia

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Assessment of Plasmodium falciparum anti-malarial drug resistance markers in pfcrt and pfmdr1 genes in isolates from Honduras and Nicaragua, 2018–2021

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Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number

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Low prevalence of copy number variation in pfmdr1 and pfpm2 in Plasmodium falciparum isolates from southern Angola

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Plasmodium falciparum Drug Resistance Phenotype as Assessed by Patient Antimalarial Drug Levels and Its Association With pfmdr1 Polymorphisms

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Asymptomatic malaria infections and Pfmdr1 mutations in an endemic area of Nigeria

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Antimalarial drug resistance in the Central and Adamawa regions of Cameroon: Prevalence of mutations in P. falciparum crt, Pfmdr1, Pfdhfr and Pfdhps genes

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Assessment of Plasmodium falciparum PfMDR1 transport rates using Fluo‐4

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Assessment of Plasmodium falciparum anti-malarial drug resistance markers in pfk13-propeller, pfcrt and pfmdr1 genes in isolates from treatment failure patients in Democratic Republic of Congo, 2018–2...

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