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ArticlesPeer ReviewedFull Text
The Antitumor Activity of Piplartine: A Review
Author / Creator:Duarte, Allana Brunna S. ; Gomes, Rebeca C. ; Nunes, Vitória Regina V. ; Gonçalves, Juan Carlos R. ; Correia, Camylla A. ; dos Santos, Ana Zulmira G. ; de Sousa, Damião P.
Publisher:Basel: MDPI AG
Journal title:Pharmaceuticals (Basel, Switzerland), 2023-09, Vol.16 (9), p.1246
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Piplartine Analogues and Cytotoxic Evaluation against Glioblastoma
Author / Creator:Da Nóbrega, Flávio Rogério ; Ozdemir, Ozlem ; Nascimento Sousa, Sheila Cristina S. ; Barboza, Joice Nascimento ; Turkez, Hasan ; De Sousa, Damião Pergentino
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2018-06, Vol.23 (6), p.1382
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Structure–Activity Relationship of Piplartine and Synthetic Analogues against Schistosoma mansoni and Cytotoxicity to Mammalian Cells
Author / Creator:Campelo, Yuri ; Ombredane, Alicia ; Vasconcelos, Andreanne ; Albuquerque, Lucas ; Moreira, Daniel ; Plácido, Alexandra ; Rocha, Jefferson ; Hilarion Fokoue, Harold ; Yamaguchi, Lydia ; Mafud, Ana ; Mascarenhas, Yvonne ; Delerue-Matos, Cristina ; Borges, Tatiana ; Joanitti, Graziella ; Arcanjo, Daniel ; Kato, Massuo ; Kuckelhaus, Selma ; Silva, Marcos ; De Moraes, Josué ; Leite, José
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2018-06, Vol.19 (6), p.1802
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Molecular Modeling and In Vitro Evaluation of Piplartine Analogs against Oral Squamous Cell Carcinoma
Author / Creator:Silva, Rayanne H. N. ; Machado, Thaíssa Q. ; da Fonseca, Anna Carolina C. ; Tejera, Eduardo ; Perez-Castillo, Yunierkis ; Robbs, Bruno K. ; de Sousa, Damião P.
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2023-02, Vol.28 (4), p.1675
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Piplartine-Inspired 3,4,5-Trimethoxycinnamates: Trypanocidal, Mechanism of Action, and In Silico Evaluation
Author / Creator:Filho, Carlos S. M. B. ; de Menezes, Ramon R. P. P. B. ; Magalhães, Emanuel P. ; Castillo, Yunierkis P. ; Martins, Alice M. C. ; de Sousa, Damião P.
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2023-06, Vol.28 (11), p.4512
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Piplartine eliminates CD34 + AML stem/progenitor cells by inducing oxidative stress and suppressing NF-κB signalling
Author / Creator:Rodrigues, Ana Carolina B. da C. ; Silva, Suellen L. R. ; Dias, Ingrid R. S. B. ; Costa, Rafaela G. A. ; Oliveira, Maiara de S. ; Soares, Milena B. P. ; Dias, Rosane B. ; Valverde, Ludmila F. ; Rocha, Clarissa A. G. ; Johnson, Emily M. ; Pina, Cristina ; Bezerra, Daniel P.
Publisher:London: Nature Publishing Group UK
Journal title:Cell death discovery, 2024-03, Vol.10 (1), p.147-147, Article 147
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Biological and physical approaches on the role of piplartine (piperlongumine) in cancer
Author / Creator:Henrique, Tiago ; Zanon, Caroline de F. ; Girol, Ana P. ; Stefanini, Ana Carolina Buzzo ; Contessoto, Nayara S. de A. ; da Silveira, Nelson J. F. ; Bezerra, Daniel P. ; Silveira, Edilberto R. ; Barbosa-Filho, José M. ; Cornélio, Marinonio L. ; Oliani, Sonia M. ; Tajara, Eloiza H.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-12, Vol.10 (1), p.22283-14, Article 22283
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(E)-Piplartine Isolated from Piper pseudoarboreum, a Lead Compound against Leishmaniasis
Author / Creator:Ticona, Juan C. ; Bilbao-Ramos, Pablo ; Flores, Ninoska ; Dea-Ayuela, M. Auxiliadora ; Bolás-Fernández, Francisco ; Jiménez, Ignacio A. ; Bazzocchi, Isabel L.
Publisher:Basel: MDPI AG
Journal title:Foods, 2020-09, Vol.9 (9), p.1250
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Protective Effect of Piplartine against LPS-Induced Sepsis through Attenuating the MAPKs/NF-κB Signaling Pathway and NLRP3 Inflammasome Activation
Author / Creator:Huang, Chi-Han ; Wang, Shu-Chi ; Chen, I-Chen ; Chen, Yi-Ting ; Liu, Po-Len ; Fang, Shih-Hua ; Huang, Shu-Pin ; Yeh, Hsin-Chih ; Liu, Ching-Chih ; Lee, Po-Yen ; Lin, Tzu-Chieh ; Cheng, Wei-Chung ; Su, Chia-Cheng ; Wu, Hsin-En ; Chen, Yuan-Ru ; Li, Chia-Yang
Publisher:Basel: MDPI AG
Journal title:Pharmaceuticals (Basel, Switzerland), 2021-06, Vol.14 (6), p.588
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Bioassay-Guided Isolation of Piplartine from Piper purusanum Yunck , and Non-Target Animals
Author / Creator:de Oliveira, André Correa ; da Silva, Felipe Moura Araujo ; de Sá, Ingrity Suelen ; Leocadio, Brenda Reis Coelho ; Lima, Suelen Costa ; Lima da Costa, Maria Luiza ; Roque, Rosemary Aparecida ; Nunomura, Rita de Cássia Saraiva
Publisher:MDPI AG
Journal title:Plants (Basel), 2025-03, Vol.14 (5)
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Trypanosoma cruzi: analysis of two different strains after piplartine treatment
Author / Creator:Vieira, Gabriela Alves Licursi ; Silva, Marco Túlio Alves da ; Regasini, Luis Octávio ; Cotinguiba, Fernando ; Laure, Helen Julie ; Rosa, José César ; Furlan, Maysa ; Cicarelli, Regina Maria Barretto
Publisher:Brazil: Elsevier Editora Ltda
Journal title:The Brazilian journal of infectious diseases, 2018-05, Vol.22 (3), p.208-218
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Unprecedented intermolecular transamidation reaction of piplartine
Author / Creator:Gowri, P. Mangala ; Radhakrishnan, S. V. S. ; Rao, V. Rama Subba ; Madnu, A. ; Hymavathi, A. ; Rao, J. Madhusudana
Publisher:Current Science Association
Journal title:Current science (Bangalore), 2015-11, Vol.109 (10), p.1775-1777
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Piplartine attenuates the proliferation of hepatocellular carcinoma cells via regulating hsa_circ_100338 expression
Author / Creator:Cheng, Xiaoli ; Tian, Pan ; Zheng, Wengzhong ; Yan, Xuetao
Publisher:United States: John Wiley & Sons, Inc
Journal title:Cancer medicine (Malden, MA), 2020-06, Vol.9 (12), p.4265-4273
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Effect of piplartine and cinnamides on Leishmania amazonensis, Plasmodium falciparum and on peritoneal cells of Swiss mice
Author / Creator:Keline Medeiros de Araújo-Vilges ; Stefan Vilges de Oliveira ; Shirley Claudino Pereira Couto ; Fokoue, Harold Hilarion ; Sierra Romero, Gustavo Adolfo ; Kato, Massuo Jorge ; Luiz Antonio Soares Romeiro ; José Roberto Souza Almeida Leite ; Selma Aparecida Souza Kuckelhaus
Publisher:Abingdon: Taylor & Francis Ltd
Journal title:Pharmaceutical biology, 2017-01, Vol.55 (1), p.1601-1607
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Piplartine Synthetic Analogs: In Silico Analysis and Antiparasitic Study against Trypanosoma cruzi
Author / Creator:Silva, Rayanne H. N. ; Magalhães, Emanuel P. ; Gomes, Rebeca C. ; Perez-Castillo, Yunierkis ; Martins, Alice M. C. ; de Sousa, Damião P.
Publisher:Basel: MDPI AG
Journal title:Applied sciences, 2023-10, Vol.13 (20), p.11585
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Piplartine Synthetic Analogs: In Silico Analysis and Antiparasitic Study against ITrypanosoma cruzi/I
Author / Creator:Silva, Rayanne H. N ; Magalhães, Emanuel P ; Gomes, Rebeca C ; Perez-Castillo, Yunierkis ; Ma ; de Sousa, Damião P
Publisher:MDPI AG
Journal title:Applied sciences, 2023-10, Vol.13 (20)
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Trypanosoma cruzi: analysis of two different strains after piplartine treatment Trypanosoma cruzi: analysis of two different strains after piplartine treatment
Author / Creator:Gabriela Alves Licursi Vieira ; Marco Túlio Alves da Silva ; Luis Octávio Regasini ; Fernando Cotinguiba ; Helen Julie Laure ; José César Rosa ; Maysa Furlan ; Regina Maria Barretto Cicarelli
Publisher:Elsevier
Journal title:The Brazilian journal of infectious diseases, 2018-05, Vol.22 (3), p.208-218
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Schistosomiasis Control Using Piplartine against Biomphalaria glabrata at Different Developmental Stages
Author / Creator:Rapado, Ludmila Nakamura ; Pinheiro, Alessandro de Sá ; Lopes, Priscila Orechio de Moraes Victor ; Fokoue, Harold Hilarion ; Scotti, Marcus Tullius ; Marques, Joaquim Vogt ; Ohlweiler, Fernanda Pires ; Borrely, Sueli Ivone ; Pereira, Carlos Alberto de Bragança ; Kato, Massuo Jorge ; Nakano, Eliana ; Yamaguchi, Lydia Fumiko
Publisher:United States: Public Library of Science
Journal title:PLoS neglected tropical diseases, 2013-06, Vol.7 (6), p.e2251
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Design, Antileishmanial Activity, and QSAR Studies of a Series of Piplartine Analogues
Author / Creator:de Sousa, Damião Pergentino ; Bezerra, Daniel Pereira ; Perez-Castillo, Yunierkis ; Lima, Tamires Cardoso ; Bezerra Filho, Carlos da Silva M. ; Silva, Larisse V. ; Nóbrega, Flávio R. ; Lima, Tatjana K. Souza
Publisher:Cairo, Egypt: Hindawi Publishing Corporation
Journal title:Journal of chemistry, 2019-01, Vol.2019 (2019), p.1-12
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Piplartine, an amide alkaloid from Piper tuberculatum, presents anxiolytic and antidepressant effects in mice
Author / Creator:Cícero Bezerra Felipe, F. ; Trajano Sousa Filho, Jucélio ; de Oliveira Souza, Louise Emanuele ; Alexandre Silveira, Jefferson ; Esdras de Andrade Uchoa, Daniel ; Rocha Silveira, Edilberto ; Deusdênia Loiola Pessoa, Otília ; de Barros Viana, Glauce S.
Publisher:Germany: Elsevier GmbH
Journal title:Phytomedicine (Stuttgart), 2007-09, Vol.14 (9), p.605-612
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Showing 1 to 20 of 94 results

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The Antitumor Activity of Piplartine: A Review

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Piplartine Analogues and Cytotoxic Evaluation against Glioblastoma

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Structure–Activity Relationship of Piplartine and Synthetic Analogues against Schistosoma mansoni and Cytotoxicity to Mammalian Cells

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Molecular Modeling and In Vitro Evaluation of Piplartine Analogs against Oral Squamous Cell Carcinoma

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Piplartine-Inspired 3,4,5-Trimethoxycinnamates: Trypanocidal, Mechanism of Action, and In Silico Evaluation

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Piplartine eliminates CD34 + AML stem/progenitor cells by inducing oxidative stress and suppressing NF-κB signalling

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Biological and physical approaches on the role of piplartine (piperlongumine) in cancer

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(E)-Piplartine Isolated from Piper pseudoarboreum, a Lead Compound against Leishmaniasis

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Protective Effect of Piplartine against LPS-Induced Sepsis through Attenuating the MAPKs/NF-κB Signaling Pathway and NLRP3 Inflammasome Activation

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Bioassay-Guided Isolation of Piplartine from Piper purusanum Yunck , and Non-Target Animals

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Trypanosoma cruzi: analysis of two different strains after piplartine treatment

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Unprecedented intermolecular transamidation reaction of piplartine

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Piplartine attenuates the proliferation of hepatocellular carcinoma cells via regulating hsa_circ_100338 expression

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Effect of piplartine and cinnamides on Leishmania amazonensis, Plasmodium falciparum and on peritoneal cells of Swiss mice

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Piplartine Synthetic Analogs: In Silico Analysis and Antiparasitic Study against Trypanosoma cruzi

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Piplartine Synthetic Analogs: In Silico Analysis and Antiparasitic Study against ITrypanosoma cruzi/I

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Trypanosoma cruzi: analysis of two different strains after piplartine treatment Trypanosoma cruzi: analysis of two different strains after piplartine treatment

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Schistosomiasis Control Using Piplartine against Biomphalaria glabrata at Different Developmental Stages

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Design, Antileishmanial Activity, and QSAR Studies of a Series of Piplartine Analogues

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Piplartine, an amide alkaloid from Piper tuberculatum, presents anxiolytic and antidepressant effects in mice

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