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ArticlesPeer ReviewedFull Text
Adaptive antibody diversification through N-linked glycosylation of the immunoglobulin variable region
Author / Creator:van de Bovenkamp, Fleur S. ; Derksen, Ninotska I. L. ; Heer, Pleuni Ooijevaar-de ; van Schie, Karin A. ; Kruithof, Simone ; Berkowska, Magdalena A. ; van der Schoot, C. Ellen ; IJspeert, Hanna ; van der Burg, Mirjam ; Gils, Ann ; Hafkenscheid, Lise ; Toes, René E. M. ; Rombouts, Yoann ; Plomp, Rosina ; Wuhrer, Manfred ; van Ham, S. Marieke ; Vidarsson, Gestur ; Rispens, Theo
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2018-02, Vol.115 (8), p.1901-1906
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ArticlesPeer ReviewedFull Text
Antigen-specific Fab profiling achieves molecular-resolution analysis of human autoantibody repertoires in rheumatoid arthritis
Author / Creator:Stork, Eva Maria ; van Rijswijck, Danique M. H. ; van Schie, Karin A. ; Hoek, Max ; Kissel, Theresa ; Scherer, Hans Ulrich ; Huizinga, Tom W. J. ; Heck, Albert J. R. ; Toes, Rene E. M. ; Bondt, Albert
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-04, Vol.15 (1), p.3114-3114, Article 3114
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ArticlesPeer ReviewedFull Text
Distinct clinical outcomes based on multiple serum cytokine and chemokine profiles rather than autoantibody profiles and ultrasound findings in rheumatoid arthritis: a prospective ultrasound cohort st...
Author / Creator:Fukui, Shoichi ; Michitsuji, Tohru ; Endo, Yushiro ; Nishino, Ayako ; Furukawa, Kaori ; Morimoto, Shimpei ; Shimizu, Toshimasa ; Umeda, Masataka ; Sumiyoshi, Remi ; Koga, Tomohiro ; Iwamoto, Naoki ; Tamai, Mami ; Origuchi, Tomoki ; van Schie, Karin A J ; Ueki, Yukitaka ; Eiraku, Nobutaka ; Yoshitama, Tamami ; Matsuoka, Naoki ; Suzuki, Takahisa ; Okada, Akitomo ; Hamada, Hiroaki ; Ayano, Masahiro ; Hidaka, Toshihiko ; Tsuru, Tomomi ; Maeda, Takahiro ; Huizinga, Tom W J ; Toes, René E M ; Kawakami, Atsushi ; Kawashiri, Shin-Ya
Publisher:England: EULAR
Journal title:Rheumatic & musculoskeletal diseases open, 2025-01, Vol.11 (1), p.e005163
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ArticlesPeer ReviewedFull Text
Type 17-specific immune pathways are active in early spondyloarthritis
Author / Creator:Hughes, Catherine D ; Ryan, Sarah E ; Steel, Kathryn J A ; van den Beukel, Michelle D ; Trouw, L A ; van Schie, Karin A J ; Toes, René E M ; Menon, Bina ; Kirkham, Bruce W ; Taams, Leonie S
Publisher:England: EULAR
Journal title:Rheumatic & musculoskeletal diseases open, 2023-12, Vol.9 (4), p.e003328
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ArticlesPeer ReviewedFull Text
Acetylated bacterial proteins as potent antigens inducing an anti-modified protein antibody response
Author / Creator:Volkov, Mikhail ; Kampstra, Arieke S B ; van Schie, Karin A J ; van Mourik, Anouk G ; Kwekkeboom, Joanneke C ; de Ru, Arnoud ; van Veelen, Peter A ; Huizinga, Tom W J ; Toes, René E M ; van der Woude, Diane
Publisher:England: EULAR
Journal title:Rheumatic & musculoskeletal diseases open, 2024-07, Vol.10 (3), p.e004411
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ArticlesPeer ReviewedFull Text
Therapeutic TNF Inhibitors can Differentially Stabilize Trimeric TNF by Inhibiting Monomer Exchange
Author / Creator:van Schie, Karin A. ; Ooijevaar-de Heer, Pleuni ; Dijk, Lisanne ; Kruithof, Simone ; Wolbink, Gertjan ; Rispens, Theo
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-09, Vol.6 (1), p.32747-32747, Article 32747
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ArticlesPeer ReviewedFull Text
Neutrophil Depletion Changes the N-Glycosylation Pattern of IgG in Experimental Murine Sepsis
Author / Creator:Yaykasli, Kursat O. ; van Schie, Karin A. ; Toes, René E. M. ; Wuhrer, Manfred ; Koeleman, Carolien A. M. ; Bila, Galyna ; Negrych, Nazar ; Schett, Georg ; Knopf, Jasmin ; Herrmann, Martin ; Bilyy, Rostyslav
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2024-06, Vol.25 (12), p.6478
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ArticlesPeer ReviewedFull Text
Restricted immune activation and internalisation of anti-idiotype complexes between drug and antidrug antibodies
Author / Creator:van Schie, Karin A ; Kruithof, Simone ; Ooijevaar-de Heer, Pleuni ; Derksen, Ninotska I L ; van de Bovenkamp, Fleur S ; Saris, Anno ; Vidarsson, Gestur ; Bentlage, Arthur E H ; Jiskoot, Wim ; Romeijn, Stefan ; Koning, Roman I ; Bos, Erik ; Stork, Eva Maria ; Koeleman, Carolien A M ; Wuhrer, Manfred ; Wolbink, Gertjan ; Rispens, Theo
Publisher:England: Elsevier B.V
Journal title:Annals of the rheumatic diseases, 2018-10, Vol.77 (10), p.1471-1479
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ArticlesPeer ReviewedFull Text
On the presence of HLA-SE alleles and ACPA-IgG variable domain glycosylation in the phase preceding the development of rheumatoid arthritis
Author / Creator:Kissel, Theresa ; van Schie, Karin Anna ; Hafkenscheid, Lise ; Lundquist, Anders ; Kokkonen, Heidi ; Wuhrer, Manfred ; Huizinga, Tom WJ ; Scherer, Hans Ulrich ; Toes, René ; Rantapää-Dahlqvist, Solbritt
Publisher:England: Elsevier Limited
Journal title:Annals of the rheumatic diseases, 2019-12, Vol.78 (12), p.1616-1620
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ArticlesPeer ReviewedFull Text
Infusion reactions during infliximab treatment are not associated with IgE anti-infliximab antibodies
Author / Creator:van Schie, Karin A ; Ooijevaar-De Heer, Pleuni ; Kruithof, Simone ; Plasencia, Chamaida ; Jurado, Teresa ; Pascual Salcedo, Dora ; Brandse, Johannan F ; d'Haens, Geert RAM ; Wolbink, Gerrit Jan ; Rispens, Theo
Publisher:England: Elsevier Limited
Journal title:Annals of the rheumatic diseases, 2017-07, Vol.76 (7), p.1285-1288
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ArticlesPeer ReviewedFull Text
OP0333 RISING ACPA IGG VARIABLE DOMAIN GLYCOSYLATION PRE-DISEASE ASSOCIATES WITH AN INCREASE IN AUTOANTIBODY LEVELS AND THE DEVELOPMENT OF RHEUMATOID ARTHRITIS
Author / Creator:Kissel, Theresa ; Schie, Karin van ; Hafkenscheid, Lise ; Lundquist, Anders ; Scherer, Hans Ulrich ; Kokkonen, Heidi ; Toes, Rene ; Dahlqvist, Solbritt Rantapää
Journal title:Annals of the rheumatic diseases, 2019-06, Vol.78, p.249-250
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ArticlesPeer ReviewedFull Text
Rising ACPA igg variable domain glycosylation pre-disease associates with an increase in autoantibody levels and the development of rheumatoid arthritis
Author / Creator:Kissel, Theresa ; van Schie, Karin ; Hafkenscheid, Lise ; Lundquist, Anders ; Scherer, Hans Ulrich ; Kokkonen, Heidi ; Toes, Rene ; Rantapää-Dahlqvist, Solbritt
Journal title:Annals of the rheumatic diseases, 2019, Vol.78, p.249
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Adaptive antibody diversification through N-linked glycosylation of the immunoglobulin variable region

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Antigen-specific Fab profiling achieves molecular-resolution analysis of human autoantibody repertoires in rheumatoid arthritis

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Distinct clinical outcomes based on multiple serum cytokine and chemokine profiles rather than autoantibody profiles and ultrasound findings in rheumatoid arthritis: a prospective ultrasound cohort st...

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Type 17-specific immune pathways are active in early spondyloarthritis

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Acetylated bacterial proteins as potent antigens inducing an anti-modified protein antibody response

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Therapeutic TNF Inhibitors can Differentially Stabilize Trimeric TNF by Inhibiting Monomer Exchange

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Neutrophil Depletion Changes the N-Glycosylation Pattern of IgG in Experimental Murine Sepsis

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Restricted immune activation and internalisation of anti-idiotype complexes between drug and antidrug antibodies

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On the presence of HLA-SE alleles and ACPA-IgG variable domain glycosylation in the phase preceding the development of rheumatoid arthritis

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Infusion reactions during infliximab treatment are not associated with IgE anti-infliximab antibodies

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OP0333 RISING ACPA IGG VARIABLE DOMAIN GLYCOSYLATION PRE-DISEASE ASSOCIATES WITH AN INCREASE IN AUTOANTIBODY LEVELS AND THE DEVELOPMENT OF RHEUMATOID ARTHRITIS

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Rising ACPA igg variable domain glycosylation pre-disease associates with an increase in autoantibody levels and the development of rheumatoid arthritis

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