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ArticlesPeer ReviewedFull Text
A Reference Standard for Evaluation of Methods for Drug Safety Signal Detection Using Electronic Healthcare Record Databases
Author / Creator:Coloma, Preciosa M. ; Avillach, Paul ; Salvo, Francesco ; Schuemie, Martijn J. ; Ferrajolo, Carmen ; Pariente, Antoine ; Fourrier-Réglat, Annie ; Molokhia, Mariam ; Patadia, Vaishali ; van der Lei, Johan ; Sturkenboom, Miriam ; Trifirò, Gianluca
Publisher:Cham: Springer International Publishing AG
Journal title:Drug safety, 2013-01, Vol.36 (1), p.13-23
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eTRANSAFE: Building a sustainable framework to share reproducible drug safety knowledge with the public domain [version 1; peer review: 2 approved]
Author / Creator:Sarntivijai, Sirarat ; Blomberg, Niklas ; Lauer, Katharina B. ; Briggs, Katharine ; Steger-Hartmann, Thomas ; van der Lei, Johan ; Sauer, John-Michael ; Liwski, Richard ; Mourby, Miranda ; Camprubi, Montse
Publisher:England: Faculty of 1000 Ltd
Journal title:F1000 research, 2022, Vol.11, p.287
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ArticlesPeer ReviewedFull Text
Risks and clinical predictors of cirrhosis and hepatocellular carcinoma diagnoses in adults with diagnosed NAFLD: real-world study of 18 million patients in four European cohorts
Author / Creator:Alexander, Myriam ; Loomis, A Katrina ; van der Lei, Johan ; Duarte-Salles, Talita ; Prieto-Alhambra, Daniel ; Ansell, David ; Pasqua, Alessandro ; Lapi, Francesco ; Rijnbeek, Peter ; Mosseveld, Mees ; Waterworth, Dawn M ; Kendrick, Stuart ; Sattar, Naveed ; Alazawi, William
Publisher:England: BioMed Central Ltd
Journal title:BMC medicine, 2019-05, Vol.17 (1), p.95-95, Article 95
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ArticlesPeer ReviewedFull Text
Non-alcoholic fatty liver disease and risk of incident acute myocardial infarction and stroke: findings from matched cohort study of 18 million European adults
Author / Creator:Alexander, Myriam ; Loomis, A Katrina ; van der Lei, Johan ; Duarte-Salles, Talita ; Prieto-Alhambra, Daniel ; Ansell, David ; Pasqua, Alessandro ; Lapi, Francesco ; Rijnbeek, Peter ; Mosseveld, Mees ; Avillach, Paul ; Egger, Peter ; Dhalwani, Nafeesa N ; Kendrick, Stuart ; Celis-Morales, Carlos ; Waterworth, Dawn M ; Alazawi, William ; Sattar, Naveed
Publisher:England: BMJ Publishing Group LTD
Journal title:BMJ (Online), 2019-10, Vol.367, p.l5367-l5367
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ArticlesPeer ReviewedFull Text
Real-world data reveal a diagnostic gap in non-alcoholic fatty liver disease
Author / Creator:Alexander, Myriam ; Loomis, A Katrina ; Fairburn-Beech, Jolyon ; van der Lei, Johan ; Duarte-Salles, Talita ; Prieto-Alhambra, Daniel ; Ansell, David ; Pasqua, Alessandro ; Lapi, Francesco ; Rijnbeek, Peter ; Mosseveld, Mees ; Avillach, Paul ; Egger, Peter ; Kendrick, Stuart ; Waterworth, Dawn M ; Sattar, Naveed ; Alazawi, William
Publisher:England: BioMed Central Ltd
Journal title:BMC medicine, 2018-08, Vol.16 (1), p.130-130, Article 130
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ArticlesPeer ReviewedFull Text
eTRANSAFE: data science to empower translational safety assessment
Author / Creator:Sanz, Ferran ; Pognan, François ; Steger-Hartmann, Thomas ; Díaz, Carlos ; Asakura, Shoji ; Amberg, Alexander ; Bécourt-Lhote, Nathalie ; Blomberg, Niklas ; Bosc, Nicolas ; Briggs, Katharine ; Bringezu, Frank ; Brulle-Wohlhueter, Claire ; Brunak, Søren ; Bueters, Ruud ; Callegaro, Giulia ; Capella-Gutierrez, Salvador ; Centeno, Emilio ; Corvi, Javier ; Cronin, Mark T. D. ; Drew, Philip ; Duchateau-Nguyen, Guillemette ; Ecker, Gerhard F. ; Escher, Sylvia ; Felix, Eloy ; Ferreiro, Miguel ; Frericks, Markus ; Furlong, Laura I. ; Geiger, Robert ; George, Catherine ; Grandits, Melanie ; Ivanov-Draganov, Dragomir ; Kilgour-Christie, Jean ; Kiziloren, Tevfik ; Kors, Jan A. ; Koyama, Naoki ; Kreuchwig, Annika ; Leach, Andrew R. ; Mayer, Miguel-Angel ; Monecke, Peter ; Muster, Wolfgang ; Nakazawa, Chihiro Miyamoto ; Nicholson, Gavin ; Parry, Rowan ; Pastor, Manuel ; Piñero, Janet ; Oberhauser, Nils ; Ramírez-Anguita, Juan Manuel ; Rodrigo, Adrián ; Smajic, Aljosa ; Schaefer, Markus ; Schieferdecker, Sebastian ; Soininen, Inari ; Terricabras, Emma ; Trairatphisan, Panuwat ; Turner, Sean C. ; Valencia, Alfonso ; van de Water, Bob ; van der Lei, Johan L. ; van Mulligen, Erik M. ; Vock, Esther ; Wilkinson, David
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Drug discovery, 2023-08, Vol.22 (8), p.605-606
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ArticlesPeer ReviewedFull Text
Evaluation of a clinical decision rule to guide antibiotic prescription in children with suspected lower respiratory tract infection in The Netherlands: A stepped-wedge cluster randomised trial
Author / Creator:van de Maat, Josephine S ; Peeters, Daphne ; Nieboer, Daan ; van Wermeskerken, Anne-Marie ; Smit, Frank J ; Noordzij, Jeroen G ; Tramper-Stranders, Gerdien ; Driessen, Gertjan J A ; Obihara, Charlie C ; Punt, Jeanine ; van der Lei, Johan ; Polinder, Suzanne ; Moll, Henriette A ; Oostenbrink, Rianne
Publisher:United States: Public Library of Science
Journal title:PLoS medicine, 2020-01, Vol.17 (1), p.e1003034-e1003034
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ArticlesPeer ReviewedFull Text
Development and validation of a clinical prediction rule for acute appendicitis in children in primary care
Author / Creator:Blok, Guus ; Burger, Huib ; van der Lei, Johan ; Berger, Marjolein ; Holtman, Gea
Publisher:England: Taylor & Francis Ltd
Journal title:The European journal of general practice, 2023-12, Vol.29 (1), p.2233053-2233053
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ArticlesPeer ReviewedFull Text
Comorbidity in incident osteoarthritis cases and matched controls using electronic health record data
Author / Creator:Kamps, Anne ; Runhaar, Jos ; de Ridder, Maria A J ; de Wilde, Marcel ; van der Lei, Johan ; Zhang, Weiya ; Prieto-Alhambra, Daniel ; Englund, Martin ; de Schepper, Evelien I T ; Bierma-Zeinstra, Sita M A
Publisher:England: BioMed Central Ltd
Journal title:Arthritis research & therapy, 2023-07, Vol.25 (1), p.114-114, Article 114
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ArticlesPeer ReviewedFull Text
A clinical prediction model to identify children at risk for revisits with serious illness to the emergency department: A prospective multicentre observational study
Author / Creator:Nijman, Ruud G ; Borensztajn, Dorine H ; Zachariasse, Joany M ; Hajema, Carine ; Freitas, Paulo ; Greber-Platzer, Susanne ; Smit, Frank J ; Alves, Claudio F ; van der Lei, Johan ; Steyerberg, Ewout W ; Maconochie, Ian K ; Moll, Henriette A
Publisher:United States: Public Library of Science
Journal title:PloS one, 2021-07, Vol.16 (7), p.e0254366
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ArticlesPeer ReviewedFull Text
Improving the prioritization of children at the emergency department: Updating the Manchester Triage System using vital signs
Author / Creator:Zachariasse, Joany M ; Maconochie, Ian K ; Nijman, Ruud G ; Greber-Platzer, Susanne ; Smit, Frank J ; Nieboer, Daan ; van der Lei, Johan ; Alves, Claudio F ; Moll, Henriëtte A
Publisher:United States: Public Library of Science
Journal title:PloS one, 2021-02, Vol.16 (2), p.e0246324-e0246324
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ArticlesPeer ReviewedFull Text
Added value of CRP to clinical features when assessing appendicitis in children
Author / Creator:Blok, Guus C. G. H. ; Nikkels, Eelke D. ; van der Lei, Johan ; Berger, Marjolein Y. ; Holtman, Gea A.
Publisher:England: Taylor & Francis
Journal title:The European journal of general practice, 2022-12, Vol.28 (1), p.95-101
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ArticlesPeer ReviewedFull Text
Shortness of breath in children at the emergency department: Variability in management in Europe
Author / Creator:Borensztajn, Dorine ; Zachariasse, Joany M ; Greber-Platzer, Susanne ; Alves, Claudio F ; Freitas, Paulo ; Smit, Frank J ; van der Lei, Johan ; Steyerberg, Ewout W ; Maconochie, Ian ; Moll, Henriëtte A
Publisher:United States: Public Library of Science
Journal title:PloS one, 2021-05, Vol.16 (5), p.e0251046-e0251046
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ArticlesPeer ReviewedFull Text
Treatment pathway analysis of newly diagnosed dementia patients in four electronic health record databases in Europe
Author / Creator:James, Glen ; Collin, Estelle ; Lawrance, Marcus ; Mueller, Achim ; Podhorna, Jana ; Zaremba-Pechmann, Liliana ; Rijnbeek, Peter ; van der Lei, Johan ; Avillach, Paul ; Pedersen, Lars ; Ansell, David ; Pasqua, Alessandro ; Mosseveld, Mees ; Grosdidier, Solène ; Gungabissoon, Usha ; Egger, Peter ; Stewart, Robert ; Celis-Morales, Carlos ; Alexander, Myriam ; Novak, Gerald ; Gordon, Mark Forrest
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Social Psychiatry and Psychiatric Epidemiology, 2021-03, Vol.56 (3), p.409-416
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ArticlesPeer ReviewedFull Text
Methotrexate and relative risk of dementia amongst patients with rheumatoid arthritis: a multi-national multi-database case-control study
Author / Creator:Newby, Danielle ; Prieto-Alhambra, Daniel ; Duarte-Salles, Talita ; Ansell, David ; Pedersen, Lars ; van der Lei, Johan ; Mosseveld, Mees ; Rijnbeek, Peter ; James, Glen ; Alexander, Myriam ; Egger, Peter ; Podhorna, Jana ; Stewart, Robert ; Perera, Gayan ; Avillach, Paul ; Grosdidier, Solène ; Lovestone, Simon ; Nevado-Holgado, Alejo J
Publisher:England: BioMed Central Ltd
Journal title:Alzheimer's research & therapy, 2020-04, Vol.12 (1), p.38-38, Article 38
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ArticlesPeer ReviewedFull Text
Manchester triage system in paediatric emergency care: prospective observational study
Author / Creator:Veen, M van ; Steyerberg, Ewout W ; Ruige, Madelon ; Meurs, Alfred H J van ; Roukema, Jolt ; Lei, Johan van der ; Moll, Henriette A
Publisher:England: British Medical Journal Publishing Group
Journal title:BMJ, 2008-10, Vol.337 (7673), p.792-795
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ArticlesPeer ReviewedFull Text
The eTRANSAFE Project on Translational Safety Assessment through Integrative Knowledge Management: Achievements and Perspectives
Author / Creator:Pognan, François ; Steger-Hartmann, Thomas ; Díaz, Carlos ; Blomberg, Niklas ; Bringezu, Frank ; Briggs, Katharine ; Callegaro, Giulia ; Capella-Gutierrez, Salvador ; Centeno, Emilio ; Corvi, Javier ; Drew, Philip ; Drewe, William C ; Fernández, José M ; Furlong, Laura I ; Guney, Emre ; Kors, Jan A ; Mayer, Miguel Angel ; Pastor, Manuel ; Piñero, Janet ; Ramírez-Anguita, Juan Manuel ; Ronzano, Francesco ; Rowell, Philip ; Saüch-Pitarch, Josep ; Valencia, Alfonso ; van de Water, Bob ; van der Lei, Johan ; van Mulligen, Erik ; Sanz, Ferran
Publisher:Switzerland: MDPI
Journal title:Pharmaceuticals (Basel, Switzerland), 2021-03, Vol.14 (3), p.237
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ArticlesPeer ReviewedFull Text
Impact of a clinical decision model for febrile children at risk for serious bacterial infections at the emergency department: a randomized controlled trial
Author / Creator:de Vos-Kerkhof, Evelien ; Nijman, Ruud G ; Vergouwe, Yvonne ; Polinder, Suzanne ; Steyerberg, Ewout W ; van der Lei, Johan ; Moll, Henriëtte A ; Oostenbrink, Rianne
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-05, Vol.10 (5), p.e0127620-e0127620
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ArticlesPeer ReviewedFull Text
The association of vascular disorders with incident dementia in different age groups
Author / Creator:Legdeur, Nienke ; van der Lee, Sven J ; de Wilde, Marcel ; van der Lei, Johan ; Muller, Majon ; Maier, Andrea B ; Visser, Pieter Jelle
Publisher:England: BioMed Central Ltd
Journal title:Alzheimer's research & therapy, 2019-05, Vol.11 (1), p.47-47, Article 47
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ArticlesPeer ReviewedFull Text
Vascular and metabolic risk factor differences prior to dementia diagnosis: a multidatabase case–control study using European electronic health records
Author / Creator:Perera, Gayan ; Rijnbeek, P R ; Alexander, Myriam ; Ansell, David ; Avillach, Paul ; Duarte-Salles, Talita ; Gordon, Mark Forrest ; Lapi, Francesco ; Mayer, Miguel Angel ; Pasqua, Alessandro ; Pedersen, Lars ; van Der Lei, Johan ; Visser, Pieter Jelle ; Stewart, Robert
Publisher:England: British Medical Journal Publishing Group
Journal title:BMJ open, 2020-11, Vol.10 (11), p.e038753-e038753
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A Reference Standard for Evaluation of Methods for Drug Safety Signal Detection Using Electronic Healthcare Record Databases

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eTRANSAFE: Building a sustainable framework to share reproducible drug safety knowledge with the public domain [version 1; peer review: 2 approved]

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Risks and clinical predictors of cirrhosis and hepatocellular carcinoma diagnoses in adults with diagnosed NAFLD: real-world study of 18 million patients in four European cohorts

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Non-alcoholic fatty liver disease and risk of incident acute myocardial infarction and stroke: findings from matched cohort study of 18 million European adults

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Real-world data reveal a diagnostic gap in non-alcoholic fatty liver disease

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eTRANSAFE: data science to empower translational safety assessment

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Evaluation of a clinical decision rule to guide antibiotic prescription in children with suspected lower respiratory tract infection in The Netherlands: A stepped-wedge cluster randomised trial

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Development and validation of a clinical prediction rule for acute appendicitis in children in primary care

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Comorbidity in incident osteoarthritis cases and matched controls using electronic health record data

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A clinical prediction model to identify children at risk for revisits with serious illness to the emergency department: A prospective multicentre observational study

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Improving the prioritization of children at the emergency department: Updating the Manchester Triage System using vital signs

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Added value of CRP to clinical features when assessing appendicitis in children

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Shortness of breath in children at the emergency department: Variability in management in Europe

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Treatment pathway analysis of newly diagnosed dementia patients in four electronic health record databases in Europe

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Methotrexate and relative risk of dementia amongst patients with rheumatoid arthritis: a multi-national multi-database case-control study

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Manchester triage system in paediatric emergency care: prospective observational study

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The eTRANSAFE Project on Translational Safety Assessment through Integrative Knowledge Management: Achievements and Perspectives

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Impact of a clinical decision model for febrile children at risk for serious bacterial infections at the emergency department: a randomized controlled trial

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The association of vascular disorders with incident dementia in different age groups

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Vascular and metabolic risk factor differences prior to dementia diagnosis: a multidatabase case–control study using European electronic health records

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