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A nanoluciferase SARS-CoV-2 for rapid neutralization testing and screening of anti-infective drugs f...

A nanoluciferase SARS-CoV-2 for rapid neutralization testing and screening of anti-infective drugs f...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_biorxiv_primary_2020_06_22_165712

A nanoluciferase SARS-CoV-2 for rapid neutralization testing and screening of anti-infective drugs for COVID-19

About this item

Full title

A nanoluciferase SARS-CoV-2 for rapid neutralization testing and screening of anti-infective drugs for COVID-19

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2020-06

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

A high-throughput platform would greatly facilitate COVID-19 serological testing and antiviral screening. Here we report a nanoluciferase SARS-CoV-2 (SARS-CoV-2-Nluc) that is genetically stable and replicates similarly to the wild-type virus in cell culture. We demonstrate that the optimized reporter virus assay in Vero E6 cells can be used to meas...

Alternative Titles

Full title

A nanoluciferase SARS-CoV-2 for rapid neutralization testing and screening of anti-infective drugs for COVID-19

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_biorxiv_primary_2020_06_22_165712

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_biorxiv_primary_2020_06_22_165712

Other Identifiers

ISSN

2692-8205

E-ISSN

2692-8205

DOI

10.1101/2020.06.22.165712

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