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Modeling SARS-CoV-2 spike/ACE2 protein–protein interactions for predicting the binding affinity of new spike variants for ACE2, and novel ACE2 structurally related human protein targets, for COVID-19...
Author / Creator:Tragni, Vincenzo ; Preziusi, Francesca ; Laera, Luna ; Onofrio, Angelo ; Mercurio, Ivan ; Todisco, Simona ; Volpicella, Mariateresa ; De Grassi, Anna ; Pierri, Ciro Leonardo
Publisher:Cham: Springer International Publishing
Journal title:The EPMA journal, 2022-03, Vol.13 (1), p.149-175
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Transplantation of ACE2- Mesenchymal Stem Cells Improves the Outcome of Patients with COVID-19 Pneumonia
Author / Creator:Leng, Zikuan ; Zhu, Rongjia ; Hou, Wei ; Feng, Yingmei ; Yang, Yanlei ; Han, Qin ; Shan, Guangliang ; Meng, Fanyan ; Du, Dongshu ; Wang, Shihua ; Fan, Junfen ; Wang, Wenjing ; Deng, Luchan ; Shi, Hongbo ; Li, Hongjun ; Hu, Zhongjie ; Zhang, Fengchun ; Gao, Jinming ; Liu, Hongjian ; Li, Xiaoxia ; Zhao, Yangyang ; Yin, Kan ; He, Xijing ; Gao, Zhengchao ; Wang, Yibin ; Yang, Bo ; Jin, Ronghua ; Stambler, Ilia ; Lim, Lee Wei ; Su, Huanxing ; Moskalev, Alexey ; Cano, Antonio ; Chakrabarti, Sasanka ; Min, Kyung-Jin ; Ellison-Hughes, Georgina ; Caruso, Calogero ; Jin, Kunlin ; Zhao, Robert Chunhua
Publisher:United States: JKL International LLC
Journal title:Aging and disease, 2020-04, Vol.11 (2), p.216-228
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SARS-CoV-2 spike engagement of ACE2 primes S2′ site cleavage and fusion initiation
Author / Creator:Yu, Shi ; Zheng, Xu ; Zhou, Bingjie ; Li, Juan ; Chen, Mengdan ; Deng, Rong ; Wong, Gary ; Lavillette, Dimitri ; Meng, Guangxun
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2022-01, Vol.119 (1), p.1-11
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Interactions of coronaviruses with ACE2, angiotensin II, and RAS inhibitors—lessons from available evidence and insights into COVID-19
Author / Creator:Kai Hisashi ; Mamiko, Kai
Publisher:Tokyo: Nature Publishing Group
Journal title:Hypertension research, 2020-07, Vol.43 (7), p.648-654
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The protein expression profile of ACE2 in human tissues
Author / Creator:Hikmet, Feria ; Méar, Loren ; Edvinsson, Åsa ; Micke, Patrick ; Uhlén, Mathias ; Lindskog, Cecilia
Publisher:London: Nature Publishing Group UK
Journal title:Molecular systems biology, 2020-07, Vol.16 (7), p.e9610-n/a
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Individual variation of the SARS‐CoV‐2 receptor ACE2 gene expression and regulation
Author / Creator:Chen, Jiawei ; Jiang, Quanlong ; Xia, Xian ; Liu, Kangping ; Yu, Zhengqing ; Tao, Wanyu ; Gong, Wenxuan ; Han, Jing‐Dong J.
Publisher:England: John Wiley & Sons, Inc
Journal title:Aging cell, 2020-07, Vol.19 (7), p.n/a
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SARS-CoV-2 binds platelet ACE2 to enhance thrombosis in COVID-19
Author / Creator:Zhang, Si ; Liu, Yangyang ; Wang, Xiaofang ; Yang, Li ; Li, Haishan ; Wang, Yuyan ; Liu, Mengduan ; Zhao, Xiaoyan ; Xie, Youhua ; Yang, Yan ; Zhang, Shenghui ; Fan, Zhichao ; Dong, Jianzeng ; Yuan, Zhenghong ; Ding, Zhongren ; Zhang, Yi ; Hu, Liang
Publisher:England: BioMed Central Ltd
Journal title:Journal of hematology and oncology, 2020-09, Vol.13 (1), p.120-22, Article 120
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Engineered ACE2 receptor traps potently neutralize SARS-CoV-2
Author / Creator:Glasgow, Anum ; Glasgow, Jeff ; Limonta, Daniel ; Solomon, Paige ; Lui, Irene ; Zhang, Yang ; Nix, Matthew A. ; Rettko, Nicholas J. ; Zha, Shoshana ; Yamin, Rachel ; Kao, Kevin ; Rosenberg, Oren S. ; Ravetch, Jeffrey V. ; Wiita, Arun P. ; Leung, Kevin K. ; Lim, Shion A. ; Zhou, Xin X. ; Hobman, Tom C. ; Kortemme, Tanja ; Wells, James A.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2020-11, Vol.117 (45), p.28046-28055
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ACE2: The Major Cell Entry Receptor for SARS-CoV-2
Author / Creator:Scialo, Filippo ; Daniele, Aurora ; Amato, Felice ; Pastore, Lucio ; Matera, Maria Gabriella ; Cazzola, Mario ; Castaldo, Giuseppe ; Bianco, Andrea
Publisher:New York: Springer US
Journal title:Lung, 2020-12, Vol.198 (6), p.867-877
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ACE2 binding is an ancestral and evolvable trait of sarbecoviruses
Author / Creator:Starr, Tyler N. ; Zepeda, Samantha K. ; Walls, Alexandra C. ; Greaney, Allison J. ; Alkhovsky, Sergey ; Veesler, David ; Bloom, Jesse D.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2022-03, Vol.603 (7903), p.913-918
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Development of ACE2 autoantibodies after SARS-CoV-2 infection
Author / Creator:Arthur, John M. ; Forrest, J. Craig ; Boehme, Karl W. ; Kennedy, Joshua L. ; Owens, Shana ; Herzog, Christian ; Liu, Juan ; Harville, Terry O.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2021-09, Vol.16 (9), p.e0257016
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Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor
Author / Creator:Lan, Jun ; Ge, Jiwan ; Yu, Jinfang ; Shan, Sisi ; Zhou, Huan ; Fan, Shilong ; Zhang, Qi ; Shi, Xuanling ; Wang, Qisheng ; Zhang, Linqi ; Wang, Xinquan
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2020-05, Vol.581 (7807), p.215-220
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Loss of ACE2 Exaggerates High-Calorie Diet–Induced Insulin Resistance by Reduction of GLUT4 in Mice
Author / Creator:Takeda, Masao ; Yamamoto, Koichi ; Takemura, Yukihiro ; Takeshita, Hikari ; Hongyo, Kazuhiro ; Kawai, Tatsuo ; Hanasaki-Yamamoto, Hiroko ; Oguro, Ryosuke ; Takami, Yoichi ; Tatara, Yuji ; Takeya, Yasushi ; Sugimoto, Ken ; Kamide, Kei ; Ohishi, Mitsuru ; Rakugi, Hiromi
Publisher:Alexandria, VA: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2013-01, Vol.62 (1), p.223-233
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ACE2 and COVID-19 and the resulting ARDS
Author / Creator:Zhang, Xiaoqing ; Li, Shuren ; Niu, Shaoqian
Publisher:England: Oxford University Press
Journal title:Postgraduate medical journal, 2020-07, Vol.96 (1137), p.403-407
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Angiotensin Converting Enzyme (ACE) and ACE2 Bind Integrins and ACE2 Regulates Integrin Signalling
Author / Creator:Clarke, Nicola E. ; Fisher, Martin J. ; Porter, Karen E. ; Lambert, Daniel W. ; Turner, Anthony J.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-04, Vol.7 (4), p.e34747
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Broad host range of SARS-CoV-2 predicted by comparative and structural analysis of ACE2 in vertebrates
Author / Creator:Damas, Joana ; Hughes, Graham M. ; Keough, Kathleen C. ; Painter, Corrie A. ; Persky, Nicole S. ; Corbo, Marco ; Hiller, Michael ; Koepfli, Klaus-Peter ; Pfenning, Andreas R. ; Zhao, Huabin ; Genereux, Diane P. ; Swofford, Ross ; Pollard, Katherine S. ; Ryder, Oliver A. ; Nweeia, Martin T. ; Lindblad-Toh, Kerstin ; Teeling, Emma C. ; Karlssonn, Elinor K. ; Lewin, Harris A.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2020-09, Vol.117 (36), p.22311-22322
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COVID-19: angiotensin-converting enzyme 2 (ACE2) expression and tissue susceptibility to SARS-CoV-2 infection
Author / Creator:Beyerstedt Stephany ; Barbosa, Casaro Expedito ; Rangel, Érika Bevilaqua
Publisher:Heidelberg: Springer Nature B.V
Journal title:European journal of clinical microbiology & infectious diseases, 2021-05, Vol.40 (5), p.905-919
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Antibody neutralization of SARS-CoV-2 through ACE2 receptor mimicry
Author / Creator:Ge, Jiwan ; Wang, Ruoke ; Ju, Bin ; Zhang, Qi ; Sun, Jing ; Chen, Peng ; Zhang, Senyan ; Tian, Yuling ; Shan, Sisi ; Cheng, Lin ; Zhou, Bing ; Song, Shuo ; Zhao, Juanjuan ; Wang, Haiyan ; Shi, Xuanling ; Ding, Qiang ; Liu, Lei ; Zhao, Jincun ; Zhang, Zheng ; Wang, Xinquan ; Zhang, Linqi
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-01, Vol.12 (1), p.250-9, Article 250
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FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2
Author / Creator:Brevini, Teresa ; Maes, Mailis ; Webb, Gwilym J. ; John, Binu V. ; Fuchs, Claudia D. ; Buescher, Gustav ; Wang, Lu ; Griffiths, Chelsea ; Brown, Marnie L. ; Scott, William E. ; Pereyra-Gerber, Pehuén ; Gelson, William T. H. ; Brown, Stephanie ; Dillon, Scott ; Muraro, Daniele ; Sharp, Jo ; Neary, Megan ; Box, Helen ; Tatham, Lee ; Stewart, James ; Curley, Paul ; Pertinez, Henry ; Forrest, Sally ; Mlcochova, Petra ; Varankar, Sagar S. ; Darvish-Damavandi, Mahnaz ; Mulcahy, Victoria L. ; Kuc, Rhoda E. ; Williams, Thomas L. ; Heslop, James A. ; Rossetti, Davide ; Tysoe, Olivia C. ; Galanakis, Vasileios ; Vila-Gonzalez, Marta ; Crozier, Thomas W. M. ; Bargehr, Johannes ; Sinha, Sanjay ; Upponi, Sara S. ; Fear, Corrina ; Swift, Lisa ; Saeb-Parsy, Kourosh ; Davies, Susan E. ; Wester, Axel ; Hagström, Hannes ; Melum, Espen ; Clements, Darran ; Humphreys, Peter ; Herriott, Jo ; Kijak, Edyta ; Cox, Helen ; Bramwell, Chloe ; Valentijn, Anthony ; Illingworth, Christopher J. R. ; Dahman, Bassam ; Bastaich, Dustin R. ; Ferreira, Raphaella D. ; Marjot, Thomas ; Barnes, Eleanor ; Moon, Andrew M. ; Barritt, Alfred S. ; Gupta, Ravindra K. ; Baker, Stephen ; Davenport, Anthony P. ; Corbett, Gareth ; Gorgoulis, Vassilis G. ; Buczacki, Simon J. A. ; Lee, Joo-Hyeon ; Matheson, Nicholas J. ; Trauner, Michael ; Fisher, Andrew J. ; Gibbs, Paul ; Butler, Andrew J. ; Watson, Christopher J. E. ; Mells, George F. ; Dougan, Gordon ; Owen, Andrew ; Lohse, Ansgar W. ; Vallier, Ludovic ; Sampaziotis, Fotios
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2023-03, Vol.615 (7950), p.134-142
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Molecular interaction and inhibition of SARS-CoV-2 binding to the ACE2 receptor
Author / Creator:Yang, Jinsung ; Petitjean, Simon J. L. ; Koehler, Melanie ; Zhang, Qingrong ; Dumitru, Andra C. ; Chen, Wenzhang ; Derclaye, Sylvie ; Vincent, Stéphane P. ; Soumillion, Patrice ; Alsteens, David
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-09, Vol.11 (1), p.4541-10, Article 4541
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Modeling SARS-CoV-2 spike/ACE2 protein–protein interactions for predicting the binding affinity of new spike variants for ACE2, and novel ACE2 structurally related human protein targets, for COVID-19...

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Transplantation of ACE2- Mesenchymal Stem Cells Improves the Outcome of Patients with COVID-19 Pneumonia

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SARS-CoV-2 spike engagement of ACE2 primes S2′ site cleavage and fusion initiation

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Interactions of coronaviruses with ACE2, angiotensin II, and RAS inhibitors—lessons from available evidence and insights into COVID-19

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The protein expression profile of ACE2 in human tissues

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Individual variation of the SARS‐CoV‐2 receptor ACE2 gene expression and regulation

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SARS-CoV-2 binds platelet ACE2 to enhance thrombosis in COVID-19

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Engineered ACE2 receptor traps potently neutralize SARS-CoV-2

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ACE2: The Major Cell Entry Receptor for SARS-CoV-2

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ACE2 binding is an ancestral and evolvable trait of sarbecoviruses

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Development of ACE2 autoantibodies after SARS-CoV-2 infection

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Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor

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Loss of ACE2 Exaggerates High-Calorie Diet–Induced Insulin Resistance by Reduction of GLUT4 in Mice

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ACE2 and COVID-19 and the resulting ARDS

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Angiotensin Converting Enzyme (ACE) and ACE2 Bind Integrins and ACE2 Regulates Integrin Signalling

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Broad host range of SARS-CoV-2 predicted by comparative and structural analysis of ACE2 in vertebrates

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COVID-19: angiotensin-converting enzyme 2 (ACE2) expression and tissue susceptibility to SARS-CoV-2 infection

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Antibody neutralization of SARS-CoV-2 through ACE2 receptor mimicry

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FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2

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Molecular interaction and inhibition of SARS-CoV-2 binding to the ACE2 receptor

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