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Bicyclol protects HepG2 cells against D-galacto-samine-induced apoptosis through inducing heat shock...

Bicyclol protects HepG2 cells against D-galacto-samine-induced apoptosis through inducing heat shock...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_chongqing_backfile_33233422

Bicyclol protects HepG2 cells against D-galacto-samine-induced apoptosis through inducing heat shock protein 27 and mitochondria associated pathway

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Full title

Bicyclol protects HepG2 cells against D-galacto-samine-induced apoptosis through inducing heat shock protein 27 and mitochondria associated pathway

Author / Creator

Journal title

Acta pharmacologica Sinica, 2010 (2), p.219-226

Language

English

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Scope and Contents

Contents

Aim: To study the inducing effect of bicyclol on heat shock protein 27 (HSP27) and its role on anti-apoptosis in HepG2 cells intoxicated with D-galactosamine (D-GaIN). Methods: HepG2 cells were treated with various concentrations of bicyclol and then subjected to D-GaIN intoxication. Apoptosis was assayed by hoechst 33258 staining and flow cytometr...

Alternative Titles

Full title

Bicyclol protects HepG2 cells against D-galacto-samine-induced apoptosis through inducing heat shock protein 27 and mitochondria associated pathway

Authors, Artists and Contributors

Author / Creator

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Primary Identifiers

Record Identifier

TN_cdi_chongqing_backfile_33233422

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_chongqing_backfile_33233422

Other Identifiers

ISSN

1671-4083

E-ISSN

1745-7254

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