Structural characterization of filaments formed by human Xrcc4-Cernunnos/XLF complex involved in non...
Structural characterization of filaments formed by human Xrcc4-Cernunnos/XLF complex involved in nonhomologous DNA end-joining
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United States: National Academy of Sciences
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English
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United States: National Academy of Sciences
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Cernunnos/XLF is a core protein of the nonhomologous DNA end-joining (NHEJ) pathway that processes the majority of DNA double-strand breaks in mammals. Cernunnos stimulates the final ligation step catalyzed by the complex between DNA ligase IV and Xrcc4 (X4). Here we present the crystal structure of the X4¹â»Â¹âµâ·-Cernunnos¹â»Â²Â²â´ complex...
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Structural characterization of filaments formed by human Xrcc4-Cernunnos/XLF complex involved in nonhomologous DNA end-joining
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TN_cdi_crossref_citationtrail_10_1073_pnas_1100758108
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_citationtrail_10_1073_pnas_1100758108
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1100758108
