Bax regulates primary necrosis through mitochondrial dynamics
Bax regulates primary necrosis through mitochondrial dynamics
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
The defining event in apoptosis is mitochondrial outer membrane permeabilization (MOMP), allowing apoptogen release. In contrast, the triggering event in primary necrosis is early opening of the inner membrane mitochondrial permeability transition pore (mPTP), precipitating mitochondrial dysfunction and cessation of ATP synthesis. Bcl-2 proteins Ba...
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Full title
Bax regulates primary necrosis through mitochondrial dynamics
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Record Identifier
TN_cdi_crossref_citationtrail_10_1073_pnas_1201608109
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_citationtrail_10_1073_pnas_1201608109
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1201608109
