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ArticlesPeer ReviewedFull Text
Immune checkpoint inhibitor–associated myocarditis: manifestations and mechanisms
Author / Creator:Moslehi, Javid ; Lichtman, Andrew H. ; Sharpe, Arlene H. ; Galluzzi, Lorenzo ; Kitsis, Richard N.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2021-03, Vol.131 (5), p.1-11
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MFN2 agonists reverse mitochondrial defects in preclinical models of Charcot-Marie-Tooth disease type 2A
Author / Creator:Rocha, Agostinho G. ; Franco, Antonietta ; Krezel, Andrzej M. ; Rumsey, Jeanne M. ; Alberti, Justin M. ; Knight, William C. ; Biris, Nikolaos ; Zacharioudakis, Emmanouil ; Janetka, James W. ; Baloh, Robert H. ; Kitsis, Richard N. ; Mochly-Rosen, Daria ; Townsend, R. Reid ; Gavathiotis, Evripidis ; Dorn, Gerald W.
Publisher:United States: The American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2018-04, Vol.360 (6386), p.336-341
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Correcting mitochondrial fusion by manipulating mitofusin conformations
Author / Creator:Franco, Antonietta ; Kitsis, Richard N. ; Fleischer, Julie A. ; Gavathiotis, Evripidis ; Kornfeld, Opher S. ; Gong, Guohua ; Biris, Nikolaos ; Benz, Ann ; Qvit, Nir ; Donnelly, Sara K. ; Chen, Yun ; Mennerick, Steven ; Hodgson, Louis ; Mochly-Rosen, Daria ; Dorn, Gerald W.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2016-12, Vol.540 (7631), p.74-79
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Modulating mitofusins to control mitochondrial function and signaling
Author / Creator:Zacharioudakis, Emmanouil ; Agianian, Bogos ; Kumar MV, Vasantha ; Biris, Nikolaos ; Garner, Thomas P. ; Rabinovich-Nikitin, Inna ; Ouchida, Amanda T. ; Margulets, Victoria ; Nordstrøm, Lars Ulrik ; Riley, Joel S. ; Dolgalev, Igor ; Chen, Yun ; Wittig, Andre J. H. ; Pekson, Ryan ; Mathew, Chris ; Wei, Peter ; Tsirigos, Aristotelis ; Tait, Stephen W. G. ; Kirshenbaum, Lorrie A. ; Kitsis, Richard N. ; Gavathiotis, Evripidis
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-07, Vol.13 (1), p.3775-3775, Article 3775
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A Rab5 endosomal pathway mediates Parkin-dependent mitochondrial clearance
Author / Creator:Hammerling, Babette C. ; Najor, Rita H. ; Cortez, Melissa Q. ; Shires, Sarah E. ; Leon, Leonardo J. ; Gonzalez, Eileen R. ; Boassa, Daniela ; Phan, Sébastien ; Thor, Andrea ; Jimenez, Rebecca E. ; Li, Hong ; Kitsis, Richard N. ; Dorn, Gerald W. ; Sadoshima, Junichi ; Ellisman, Mark H. ; Gustafsson, Åsa B.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-01, Vol.8 (1), p.14050-14050, Article 14050
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Bax regulates primary necrosis through mitochondrial dynamics
Author / Creator:Whelan, Russell S ; Konstantinidis, Klitos ; Wei, An-Chi ; Chen, Yun ; Reyna, Denis E ; Jha, Saurabh ; Yang, Ying ; Calvert, John W ; Lindsten, Tullia ; Thompson, Craig B ; Crow, Michael T ; Gavathiotis, Evripidis ; Dorn, Gerald W. II ; O'Rourke, Brian ; Kitsis, Richard N
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2012-04, Vol.109 (17), p.6566-6571
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High-Fat Diet–Induced Adipocyte Cell Death Occurs Through a Cyclophilin D Intrinsic Signaling Pathway Independent of Adipose Tissue Inflammation
Author / Creator:Feng, Daorong ; Tang, Yan ; Kwon, Hyokjoon ; Zong, Haihong ; Hawkins, Meredith ; Kitsis, Richard N. ; Pessin, Jeffrey E.
Publisher:Alexandria, VA: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2011-08, Vol.60 (8), p.2134-2143
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Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1
Author / Creator:Wang, Yidong ; Wu, Bingruo ; Lu, Pengfei ; Zhang, Donghong ; Wu, Brian ; Varshney, Shweta ; del Monte-Nieto, Gonzalo ; Zhuang, Zhenwu ; Charafeddine, Rabab ; Kramer, Adam H. ; Sibinga, Nicolas E. ; Frangogiannis, Nikolaos G. ; Kitsis, Richard N. ; Adams, Ralf H. ; Alitalo, Kari ; Sharp, David J. ; Harvey, Richard P. ; Stanley, Pamela ; Zhou, Bin
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-09, Vol.8 (1), p.578-15, Article 578
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A mechanistic role for cardiac myocyte apoptosis in heart failure
Author / Creator:Wencker, Detlef ; Chandra, Madhulika ; Nguyen, Khanh ; Miao, Wenfeng ; Garantziotis, Stavros ; Factor, Stephen M. ; Shirani, Jamshid ; Armstrong, Robert C. ; Kitsis, Richard N.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2003-05, Vol.111 (10), p.1497-1504
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Apoptotic cell death "Nixed" by an ER—mitochondrial necrotic pathway
Author / Creator:Kitsis, Richard N. ; Molkentin, Jeffery D.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2010-05, Vol.107 (20), p.9031-9032
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ARC is essential for maintaining pancreatic islet structure and β-cell viability during type 2 diabetes
Author / Creator:McKimpson, Wendy M. ; Zheng, Min ; Chua, Streamson C. ; Pessin, Jeffrey E. ; Kitsis, Richard N.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-08, Vol.7 (1), p.7019-7019, Article 7019
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OncomiR miR-182-5p Enhances Radiosensitivity by Inhibiting the Radiation-Induced Antioxidant Effect through SESN2 in Head and Neck Cancer
Author / Creator:Lin, Min-Ying ; Chang, Yu-Chan ; Wang, Shan-Ying ; Yang, Muh-Hwa ; Chang, Chih-Hsien ; Hsiao, Michael ; Kitsis, Richard N. ; Lee, Yi-Jang
Publisher:Basel: MDPI AG
Journal title:Antioxidants, 2021-11, Vol.10 (11), p.1808
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Apoptosis Repressor with a CARD Domain (ARC) Restrains Bax-Mediated Pathogenesis in Dystrophic Skeletal Muscle
Author / Creator:Davis, Jennifer ; Kwong, Jennifer Q. ; Kitsis, Richard N. ; Molkentin, Jeffery D.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-12, Vol.8 (12), p.e82053-e82053
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The Cell Death Inhibitor ARC Is Induced in a Tissue-Specific Manner by Deletion of the Tumor Suppressor Gene Men1, but Not Required for Tumor Development and Growth
Author / Creator:McKimpson, Wendy M. ; Yuan, Ziqiang ; Zheng, Min ; Crabtree, Judy S. ; Libutti, Steven K. ; Kitsis, Richard N.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-12, Vol.10 (12), p.e0145792-e0145792
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Regulation of p53 tetramerization and nuclear export by ARC
Author / Creator:Foo, Roger S.-Y ; Nam, Young-Jae ; Ostreicher, Marc Jason ; Metzl, Mark D ; Whelan, Russell S ; Peng, Chang-Fu ; Ashton, Anthony W ; Fu, Weimin ; Mani, Kartik ; Chin, Suet-Feung ; Provenzano, Elena ; Ellis, Ian ; Figg, Nichola ; Pinder, Sarah ; Bennett, Martin R ; Caldas, Carlos ; Kitsis, Richard N
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2007-12, Vol.104 (52), p.20826-20831
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A mouse model for the most common form of heart failure
Author / Creator:Amgalan, Dulguun ; Kitsis, Richard N.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2019-04, Vol.568 (7752), p.324-325
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A new mouse model for heart failure
Author / Creator:Amgalan, Dulguun ; Kitsis, Richard N
Publisher:London: Nature Publishing Group
Journal title:Nature (London), 2019-04, Vol.568 (7752), p.324-325
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Small-molecule allosteric inhibitors of BAX
Author / Creator:Garner, Thomas P. ; Amgalan, Dulguun ; Reyna, Denis E. ; Li, Sheng ; Kitsis, Richard N. ; Gavathiotis, Evripidis
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2019-04, Vol.15 (4), p.322-330
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Death begets failure in the heart
Author / Creator:Foo, Roger S.-Y. ; Mani, Kartik ; Kitsis, Richard N.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2005-03, Vol.115 (3), p.565-571
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SNAP23 regulates BAX-dependent adipocyte programmed cell death independently of canonical macroautophagy
Author / Creator:Feng, Daorong ; Amgalan, Dulguun ; Singh, Rajat ; Wei, Jianwen ; Wen, Jennifer ; Wei, Tszki Peter ; McGraw, Timothy E. ; Kitsis, Richard N. ; Pessin, Jeffrey E.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2018-09, Vol.128 (9), p.3941-3956
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Showing 1 to 20 of 43 results

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Immune checkpoint inhibitor–associated myocarditis: manifestations and mechanisms

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MFN2 agonists reverse mitochondrial defects in preclinical models of Charcot-Marie-Tooth disease type 2A

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Correcting mitochondrial fusion by manipulating mitofusin conformations

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Modulating mitofusins to control mitochondrial function and signaling

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A Rab5 endosomal pathway mediates Parkin-dependent mitochondrial clearance

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Bax regulates primary necrosis through mitochondrial dynamics

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High-Fat Diet–Induced Adipocyte Cell Death Occurs Through a Cyclophilin D Intrinsic Signaling Pathway Independent of Adipose Tissue Inflammation

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Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1

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A mechanistic role for cardiac myocyte apoptosis in heart failure

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Apoptotic cell death "Nixed" by an ER—mitochondrial necrotic pathway

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ARC is essential for maintaining pancreatic islet structure and β-cell viability during type 2 diabetes

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OncomiR miR-182-5p Enhances Radiosensitivity by Inhibiting the Radiation-Induced Antioxidant Effect through SESN2 in Head and Neck Cancer

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Apoptosis Repressor with a CARD Domain (ARC) Restrains Bax-Mediated Pathogenesis in Dystrophic Skeletal Muscle

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The Cell Death Inhibitor ARC Is Induced in a Tissue-Specific Manner by Deletion of the Tumor Suppressor Gene Men1, but Not Required for Tumor Development and Growth

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Regulation of p53 tetramerization and nuclear export by ARC

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A mouse model for the most common form of heart failure

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A new mouse model for heart failure

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Small-molecule allosteric inhibitors of BAX

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Death begets failure in the heart

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SNAP23 regulates BAX-dependent adipocyte programmed cell death independently of canonical macroautophagy

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