Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decr...
Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense
About this item
Full title
Author / Creator
Lassen, Kara G. , Kuballa, Petric , Conway, Kara L. , Patel, Khushbu K. , Becker, Christine E. , Peloquin, Joanna M. , Villablanca, Eduardo J. , Norman, Jason M. , Liu, Ta-Chiang , Heath, Robert J. , Becker, Morgan L. , Fagbami, Lola , Horn, Heiko , Mercer, Johnathan , Yilmaz, Omer H. , Jaffe, Jacob D. , Shamji, Alykhan F. , Bhan, Atul K. , Carr, Steven A. , Daly, Mark J. , Virgin, Herbert W. , Schreiber, Stuart L. , Stappenbeck, Thaddeus S. and Xavier, Ramnik J.
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
A coding polymorphism (Thr300Ala) in the essential autophagy gene, autophagy related 16-like 1 (ATG16L1), confers increased risk for the development of Crohn disease, although the mechanisms by which single disease-associated polymorphisms contribute to pathogenesis have been difficult to dissect given that environmental factors likely influence di...
Alternative Titles
Full title
Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense
Authors, Artists and Contributors
Author / Creator
Kuballa, Petric
Conway, Kara L.
Patel, Khushbu K.
Becker, Christine E.
Peloquin, Joanna M.
Villablanca, Eduardo J.
Norman, Jason M.
Liu, Ta-Chiang
Heath, Robert J.
Becker, Morgan L.
Fagbami, Lola
Horn, Heiko
Mercer, Johnathan
Yilmaz, Omer H.
Jaffe, Jacob D.
Shamji, Alykhan F.
Bhan, Atul K.
Carr, Steven A.
Daly, Mark J.
Virgin, Herbert W.
Schreiber, Stuart L.
Stappenbeck, Thaddeus S.
Xavier, Ramnik J.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_crossref_citationtrail_10_1073_pnas_1407001111
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_citationtrail_10_1073_pnas_1407001111
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1407001111
