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Pharmacological profile of NOP receptors coupled with calcium signaling via the chimeric protein Gαq...

Pharmacological profile of NOP receptors coupled with calcium signaling via the chimeric protein Gαq...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1007_s00210_009_0396_x

Pharmacological profile of NOP receptors coupled with calcium signaling via the chimeric protein Gαqi5

About this item

Full title

Pharmacological profile of NOP receptors coupled with calcium signaling via the chimeric protein Gαqi5

Publisher

Berlin/Heidelberg: Springer-Verlag

Journal title

Naunyn-Schmiedeberg's archives of pharmacology, 2009-06, Vol.379 (6), p.599-607

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer-Verlag

More information

Scope and Contents

Contents

In this study, the Gα
qi5
protein was used to force the human nociceptin/orphanin FQ (N/OFQ) peptide (NOP) receptor to signal through the Ca
2+
pathway in CHO cells. [Ca
2+
]
i
levels were monitored using the fluorometer FlexStation II and the Ca
2+
dye Fluo 4 AM. Concentration response curves were generated with a pan...

Alternative Titles

Full title

Pharmacological profile of NOP receptors coupled with calcium signaling via the chimeric protein Gαqi5

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1007_s00210_009_0396_x

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1007_s00210_009_0396_x

Other Identifiers

ISSN

0028-1298

E-ISSN

1432-1912

DOI

10.1007/s00210-009-0396-x

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