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ArticlesPeer ReviewedFull Text
The atypical chemokine receptor ACKR3/CXCR7 is a broad-spectrum scavenger for opioid peptides
Author / Creator:Meyrath, Max ; Szpakowska, Martyna ; Zeiner, Julian ; Massotte, Laurent ; Merz, Myriam P. ; Benkel, Tobias ; Simon, Katharina ; Ohnmacht, Jochen ; Turner, Jonathan D. ; Krüger, Rejko ; Seutin, Vincent ; Ollert, Markus ; Kostenis, Evi ; Chevigné, Andy
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-06, Vol.11 (1), p.3033-3033, Article 3033
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Chemokine receptor trafficking coordinates neutrophil clustering and dispersal at wounds in zebrafish
Author / Creator:Coombs, Caroline ; Georgantzoglou, Antonios ; Walker, Hazel A. ; Patt, Julian ; Merten, Nicole ; Poplimont, Hugo ; Busch-Nentwich, Elisabeth M. ; Williams, Sarah ; Kotsi, Christina ; Kostenis, Evi ; Sarris, Milka
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-11, Vol.10 (1), p.5166-17, Article 5166
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Lack of beta-arrestin signaling in the absence of active G proteins
Author / Creator:Grundmann, Manuel ; Merten, Nicole ; Malfacini, Davide ; Inoue, Asuka ; Preis, Philip ; Simon, Katharina ; Rüttiger, Nelly ; Ziegler, Nicole ; Benkel, Tobias ; Schmitt, Nina Katharina ; Ishida, Satoru ; Müller, Ines ; Reher, Raphael ; Kawakami, Kouki ; Inoue, Ayumi ; Rick, Ulrike ; Kühl, Toni ; Imhof, Diana ; Aoki, Junken ; König, Gabriele M. ; Hoffmann, Carsten ; Gomeza, Jesus ; Wess, Jürgen ; Kostenis, Evi
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-01, Vol.9 (1), p.341-16, Article 341
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Label-free biosensor assay decodes the dynamics of Toll-like receptor signaling
Author / Creator:Holze, Janine ; Lauber, Felicitas ; Soler, Sofía ; Kostenis, Evi ; Weindl, Günther
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-11, Vol.15 (1), p.9554-18, Article 9554
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Adipocyte Gq signaling is a regulator of glucose and lipid homeostasis in mice
Author / Creator:Kimura, Takefumi ; Pydi, Sai P. ; Wang, Lei ; Haspula, Dhanush ; Cui, Yinghong ; Lu, Huiyan ; König, Gabriele M. ; Kostenis, Evi ; Steinberg, Gregory R. ; Gavrilova, Oksana ; Wess, Jürgen
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-03, Vol.13 (1), p.1-17, Article 1652
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Heterotrimeric G‐proteins: a short history
Author / Creator:Milligan, Graeme ; Kostenis, Evi
Publisher:Oxford, UK: Blackwell Publishing Ltd
Journal title:British journal of pharmacology, 2006-01, Vol.147 (S1), p.S46-S55
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Thioesterase-mediated side chain transesterification generates potent Gq signaling inhibitor FR900359
Author / Creator:Hermes, Cornelia ; Richarz, René ; Wirtz, Daniel A. ; Patt, Julian ; Hanke, Wiebke ; Kehraus, Stefan ; Voß, Jan Hendrik ; Küppers, Jim ; Ohbayashi, Tsubasa ; Namasivayam, Vigneshwaran ; Alenfelder, Judith ; Inoue, Asuka ; Mergaert, Peter ; Gütschow, Michael ; Müller, Christa E. ; Kostenis, Evi ; König, Gabriele M. ; Crüsemann, Max
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-01, Vol.12 (1), p.144-144, Article 144
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Disentangling bias between Gq, GRK2, and arrestin3 recruitment to the M3 muscarinic acetylcholine receptor
Author / Creator:Flöser, Anja ; Becker, Katharina ; Kostenis, Evi ; König, Gabriele ; Krasel, Cornelius ; Kolb, Peter ; Bünemann, Moritz
Publisher:Cambridge: eLife Sciences Publications Ltd
Journal title:eLife, 2021-12, Vol.10
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NOP receptor pharmacological profile – A dynamic mass redistribution study
Author / Creator:Malfacini, Davide ; Simon, Katharina ; Trapella, Claudio ; Guerrini, Remo ; Zaveri, Nurulain T. ; Kostenis, Evi ; Calo’, Girolamo
Publisher:United States: Public Library of Science
Journal title:PloS one, 2018-08, Vol.13 (8), p.e0203021-e0203021
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Gq/11-dependent regulation of endosomal cAMP generation by parathyroid hormone class B GPCR
Author / Creator:White, Alex D. ; Jean-Alphonse, Frederic G. ; Fang, Fei ; Peña, Karina A. ; Liu, Shi ; König, Gabriele M. ; Inoue, Asuka ; Aslanoglou, Despoina ; Gellman, Samuel H. ; Kostenis, Evi ; Xiao, Kunhong ; Vilardaga, Jean-Pierre
Publisher:National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2020-03, Vol.117 (13), p.7455-7460
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Selective optogenetic control of Gq signaling using human Neuropsin
Author / Creator:Wagdi, Ahmed ; Malan, Daniela ; Sathyanarayanan, Udhayabhaskar ; Beauchamp, Janosch S. ; Vogt, Markus ; Zipf, David ; Beiert, Thomas ; Mansuroglu, Berivan ; Dusend, Vanessa ; Meininghaus, Mark ; Schneider, Linn ; Kalthof, Bernd ; Wiegert, J. Simon ; König, Gabriele M. ; Kostenis, Evi ; Patejdl, Robert ; Sasse, Philipp ; Bruegmann, Tobias
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-04, Vol.13 (1), p.1765-1765, Article 1765
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How Carvedilol activates β2-adrenoceptors
Author / Creator:Benkel, Tobias ; Zimmermann, Mirjam ; Zeiner, Julian ; Bravo, Sergi ; Merten, Nicole ; Lim, Victor Jun Yu ; Matthees, Edda Sofie Fabienne ; Drube, Julia ; Miess-Tanneberg, Elke ; Malan, Daniela ; Szpakowska, Martyna ; Monteleone, Stefania ; Grimes, Jak ; Koszegi, Zsombor ; Lanoiselée, Yann ; O’Brien, Shannon ; Pavlaki, Nikoleta ; Dobberstein, Nadine ; Inoue, Asuka ; Nikolaev, Viacheslav ; Calebiro, Davide ; Chevigné, Andy ; Sasse, Philipp ; Schulz, Stefan ; Hoffmann, Carsten ; Kolb, Peter ; Waldhoer, Maria ; Simon, Katharina ; Gomeza, Jesus ; Kostenis, Evi
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-11, Vol.13 (1), p.7109-20, Article 7109
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G protein-mediated signal transduction: a molecular choreography of G protein activation after GTP binding
Author / Creator:Kostenis, Evi ; Jürgenliemke, Lars ; Alenfelder, Judith
Publisher:London: Nature Publishing Group UK
Journal title:Signal transduction and targeted therapy, 2024-07, Vol.9 (1), p.188-3, Article 188
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A molecular mechanism to diversify Ca2+ signaling downstream of Gs protein-coupled receptors
Author / Creator:Brands, Julian ; Bravo, Sergi ; Jürgenliemke, Lars ; Grätz, Lukas ; Schihada, Hannes ; Frechen, Fabian ; Alenfelder, Judith ; Pfeil, Cy ; Ohse, Paul Georg ; Hiratsuka, Suzune ; Kawakami, Kouki ; Schmacke, Luna C. ; Heycke, Nina ; Inoue, Asuka ; König, Gabriele ; Pfeifer, Alexander ; Wachten, Dagmar ; Schulte, Gunnar ; Steinmetzer, Torsten ; Watts, Val J. ; Gomeza, Jesús ; Simon, Katharina ; Kostenis, Evi
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-09, Vol.15 (1), p.7684-21, Article 7684
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Reply to: How carvedilol does not activate β2-adrenoceptors
Author / Creator:Kostenis, Evi ; Gomeza, Jesus ; Miess-Tanneberg, Elke ; Blum, Nina Kathleen ; Benkel, Tobias ; Chevigné, Andy ; Hoffmann, Carsten ; Kolb, Peter ; Nikolaev, Viacheslav ; Waldhoer, Maria ; Szpakowska, Martyna ; Inoue, Asuka ; Schulz, Stefan
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-11, Vol.14 (1), p.7867-7867, Article 7867
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The Gq signalling pathway inhibits brown and beige adipose tissue
Author / Creator:Klepac, Katarina ; Kilić, Ana ; Gnad, Thorsten ; Brown, Loren M. ; Herrmann, Beate ; Wilderman, Andrea ; Balkow, Aileen ; Glöde, Anja ; Simon, Katharina ; Lidell, Martin E. ; Betz, Matthias J. ; Enerbäck, Sven ; Wess, Jürgen ; Freichel, Marc ; Blüher, Matthias ; König, Gabi ; Kostenis, Evi ; Insel, Paul A. ; Pfeifer, Alexander
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2016-03, Vol.7 (1), p.10895-10, Article 10895
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GPR55 regulates cannabinoid 2 receptor-mediated responses in human neutrophils
Author / Creator:Balenga, Nariman A B ; Aflaki, Elma ; Kargl, Julia ; Platzer, Wolfgang ; Schröder, Ralf ; Blättermann, Stefanie ; Kostenis, Evi ; Brown, Andrew J ; Heinemann, Akos ; Waldhoer, Maria
Publisher:London: Nature Publishing Group UK
Journal title:Cell research, 2011-10, Vol.21 (10), p.1452-1469
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Applying label-free dynamic mass redistribution technology to frame signaling of G protein–coupled receptors noninvasively in living cells
Author / Creator:Schröder, Ralf ; Schmidt, Johannes ; Blättermann, Stefanie ; Peters, Lucas ; Janssen, Nicole ; Grundmann, Manuel ; Seemann, Wiebke ; Kaufel, Dorina ; Merten, Nicole ; Drewke, Christel ; Gomeza, Jesus ; Milligan, Graeme ; Mohr, Klaus ; Kostenis, Evi
Publisher:London: Nature Publishing Group UK
Journal title:Nature protocols, 2011-11, Vol.6 (11), p.1748-1760
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FFA2-, but not FFA3-agonists inhibit GSIS of human pseudoislets: a comparative study with mouse islets and rat INS-1E cells
Author / Creator:Lorza-Gil, Estela ; Kaiser, Gabriele ; Rexen Ulven, Elisabeth ; König, Gabriele M. ; Gerst, Felicia ; Oquendo, Morgana Barroso ; Birkenfeld, Andreas L. ; Häring, Hans-Ulrich ; Kostenis, Evi ; Ulven, Trond ; Ullrich, Susanne
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-10, Vol.10 (1), p.16497-16497, Article 16497
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Deconvolution of complex G protein–coupled receptor signaling in live cells using dynamic mass redistribution measurements
Author / Creator:Schröder, Ralf ; Janssen, Nicole ; Schmidt, Johannes ; Kebig, Anna ; Merten, Nicole ; Hennen, Stephanie ; Müller, Anke ; Blättermann, Stefanie ; Mohr-Andrä, Marion ; Zahn, Sabine ; Wenzel, Jörg ; Smith, Nicola J ; Gomeza, Jesús ; Drewke, Christel ; Milligan, Graeme ; Mohr, Klaus ; Kostenis, Evi
Publisher:New York: Nature Publishing Group US
Journal title:Nature biotechnology, 2010-09, Vol.28 (9), p.943-949
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The atypical chemokine receptor ACKR3/CXCR7 is a broad-spectrum scavenger for opioid peptides

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Chemokine receptor trafficking coordinates neutrophil clustering and dispersal at wounds in zebrafish

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Lack of beta-arrestin signaling in the absence of active G proteins

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Label-free biosensor assay decodes the dynamics of Toll-like receptor signaling

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Adipocyte Gq signaling is a regulator of glucose and lipid homeostasis in mice

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Heterotrimeric G‐proteins: a short history

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Thioesterase-mediated side chain transesterification generates potent Gq signaling inhibitor FR900359

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Disentangling bias between Gq, GRK2, and arrestin3 recruitment to the M3 muscarinic acetylcholine receptor

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NOP receptor pharmacological profile – A dynamic mass redistribution study

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Gq/11-dependent regulation of endosomal cAMP generation by parathyroid hormone class B GPCR

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Selective optogenetic control of Gq signaling using human Neuropsin

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How Carvedilol activates β2-adrenoceptors

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G protein-mediated signal transduction: a molecular choreography of G protein activation after GTP binding

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A molecular mechanism to diversify Ca2+ signaling downstream of Gs protein-coupled receptors

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Reply to: How carvedilol does not activate β2-adrenoceptors

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The Gq signalling pathway inhibits brown and beige adipose tissue

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GPR55 regulates cannabinoid 2 receptor-mediated responses in human neutrophils

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Applying label-free dynamic mass redistribution technology to frame signaling of G protein–coupled receptors noninvasively in living cells

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FFA2-, but not FFA3-agonists inhibit GSIS of human pseudoislets: a comparative study with mouse islets and rat INS-1E cells

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Deconvolution of complex G protein–coupled receptor signaling in live cells using dynamic mass redistribution measurements

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