Local disposition kinetics of floxuridine after intratumoral and subcutaneous injection as monitored...
Local disposition kinetics of floxuridine after intratumoral and subcutaneous injection as monitored by [19F]-nuclear magnetic resonance spectroscopy in vivo
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Author / Creator
PORT, R , HANISCH, F , BECKER, M , BACHERT, P and ZELLER, J
Publisher
Berlin: Springer
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Language
English
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Publisher
Berlin: Springer
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Scope and Contents
Contents
To test the utility of [19F]-nuclear magnetic resonance (NMR) spectroscopy for studying the kinetics of local drug disposition after interstitial application in vivo.
Floxuridine at 30 micromol (2.5% of the reported i.p. 50% lethal dose, LD50) was injected into rats either intratumorally (Morris hepatoma M3924A) or s.c. [19F]-NMR spectra were ob...
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Full title
Local disposition kinetics of floxuridine after intratumoral and subcutaneous injection as monitored by [19F]-nuclear magnetic resonance spectroscopy in vivo
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Record Identifier
TN_cdi_crossref_primary_10_1007_s002800050946
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1007_s002800050946
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ISSN
0344-5704
E-ISSN
1432-0843
DOI
10.1007/s002800050946