Treatment of SMB-S15 Cells with Resveratrol Efficiently Removes the PrPSc Accumulation In Vitro and...
Treatment of SMB-S15 Cells with Resveratrol Efficiently Removes the PrPSc Accumulation In Vitro and Prion Infectivity In Vivo
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Author / Creator
Wang, Jing , Zhang, Bao-Yun , Zhang, Jin , Xiao, Kang , Chen, Li-Na , Wang, Hui , Sun, Jing , Shi, Qi and Dong, Xiao-Ping
Publisher
New York: Springer US
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Language
English
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New York: Springer US
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Contents
Prion diseases are transmissible and invariably fatal neurodegenerative disorders, which still lack of efficacious prophylactic and therapeutic tools. Our previous study has proposed that the natural phytoalexin, resveratrol, can reduce the amounts of PrP
Sc
in a scrapie-infected cell line SMB-S15. To address its anti-prion efficacy, the inhi...
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Full title
Treatment of SMB-S15 Cells with Resveratrol Efficiently Removes the PrPSc Accumulation In Vitro and Prion Infectivity In Vivo
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Record Identifier
TN_cdi_crossref_primary_10_1007_s12035_015_9464_z
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1007_s12035_015_9464_z
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ISSN
0893-7648
E-ISSN
1559-1182
DOI
10.1007/s12035-015-9464-z