Increased amyloid-β42(43) in brains of mice expressing mutant presenilin 1
Increased amyloid-β42(43) in brains of mice expressing mutant presenilin 1
About this item
Full title
Increased amyloid-β42(43) in brains of mice expressing mutant presenilin 1
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Nature (London), 1996-10, Vol.383 (6602), p.710-713
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
MUTATIONS in the genes encoding amyloid-β precursor protein (
APP
)
1
presenilin 1 (
PS1
)
2
and presenilin 2 (
PS2
)
3,4
are known to cause early-onset, autosomal dominant Alzheimer's disease. Studies of plasma and fibroblasts from subjects with these mutations have established that they all alter amyloid β-prot...
Alternative Titles
Full title
Increased amyloid-β42(43) in brains of mice expressing mutant presenilin 1
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_crossref_primary_10_1038_383710a0
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1038_383710a0
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/383710a0
