Hypoxia-inducible factor-1α contributes to the profibrotic action of angiotensin II in renal medulla...
Hypoxia-inducible factor-1α contributes to the profibrotic action of angiotensin II in renal medullary interstitial cells
About this item
Full title
Author / Creator
Wang, Zhengchao , Tang, Lin , Zhu, Qing , Yi, Fan , Zhang, Fan , Li, Pin-Lan and Li, Ningjun
Publisher
Basingstoke: Elsevier Inc
Journal title
Language
English
Formats
Publication information
Publisher
Basingstoke: Elsevier Inc
Subjects
More information
Scope and Contents
Contents
To examine whether hypoxia-inducible factor (HIF)-1α mediates the profibrotic effects of angiotensin II, we treated cultured renal medullary interstitial cells with angiotensin II and found that it increased HIF-1α levels. This was accompanied by a significant upregulation of collagen I/III, the tissue inhibitor of metalloproteinase-1, elevation of...
Alternative Titles
Full title
Hypoxia-inducible factor-1α contributes to the profibrotic action of angiotensin II in renal medullary interstitial cells
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_crossref_primary_10_1038_ki_2010_326
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1038_ki_2010_326
Other Identifiers
ISSN
0085-2538
E-ISSN
1523-1755
DOI
10.1038/ki.2010.326
