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Functional significance of the two ACOX1 isoforms and their crosstalks with PPARα and RXRα

Functional significance of the two ACOX1 isoforms and their crosstalks with PPARα and RXRα

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1038_labinvest_2010_46

Functional significance of the two ACOX1 isoforms and their crosstalks with PPARα and RXRα

About this item

Full title

Functional significance of the two ACOX1 isoforms and their crosstalks with PPARα and RXRα

Publisher

New York: Elsevier Inc

Journal title

Laboratory investigation, 2010-05, Vol.90 (5), p.696-708

Language

English

Formats

Publication information

Publisher

New York: Elsevier Inc

More information

Scope and Contents

Contents

Disruption of the peroxisomal acyl-CoA oxidase 1 (Acox1) gene in the mouse results in the development of severe microvesicular hepatic steatosis and sustained activation of peroxisome proliferator-activated receptor-α (PPARα). These mice manifest spontaneous massive peroxisome proliferation in regenerating hepatocytes and eventually develop hepatoc...

Alternative Titles

Full title

Functional significance of the two ACOX1 isoforms and their crosstalks with PPARα and RXRα

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1038_labinvest_2010_46

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1038_labinvest_2010_46

Other Identifiers

ISSN

0023-6837

E-ISSN

1530-0307

DOI

10.1038/labinvest.2010.46

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