Persistent cell migration and adhesion rely on retrograde transport of β1 integrin
Persistent cell migration and adhesion rely on retrograde transport of β1 integrin
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Integrins have key functions in cell adhesion and migration. How integrins are dynamically relocalized to the leading edge in highly polarized migratory cells has remained unexplored. Here, we demonstrate that β
1
integrin (known as PAT-3 in
Caenorhabditis elegans
), but not β
3
, is transported from the plasma membrane to the
Alternative Titles
Full title
Persistent cell migration and adhesion rely on retrograde transport of β1 integrin
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TN_cdi_crossref_primary_10_1038_ncb3287
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1038_ncb3287
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ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/ncb3287
