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Glucocorticoids and Lithium Reciprocally Regulate the Proliferation of Adult Dentate Gyrus-Derived N...

Glucocorticoids and Lithium Reciprocally Regulate the Proliferation of Adult Dentate Gyrus-Derived N...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1038_npp_2008_198

Glucocorticoids and Lithium Reciprocally Regulate the Proliferation of Adult Dentate Gyrus-Derived Neural Precursor Cells Through GSK-3β and β-Catenin/TCF Pathway

About this item

Full title

Glucocorticoids and Lithium Reciprocally Regulate the Proliferation of Adult Dentate Gyrus-Derived Neural Precursor Cells Through GSK-3β and β-Catenin/TCF Pathway

Publisher

Cham: Springer International Publishing

Journal title

Neuropsychopharmacology (New York, N.Y.), 2009-02, Vol.34 (3), p.805-815

Language

English

Formats

Publication information

Publisher

Cham: Springer International Publishing

More information

Scope and Contents

Contents

Adult hippocampal neurogenesis is decreased in rodent models for stress-related disorders at least partly through an elevated level of glucocorticoids. On the other hand, the mood stabilizer lithium (Li) commonly used for their treatment increases it. This effect is thought to be one of the therapeutic actions of Li, but the molecular mechanism has...

Alternative Titles

Full title

Glucocorticoids and Lithium Reciprocally Regulate the Proliferation of Adult Dentate Gyrus-Derived Neural Precursor Cells Through GSK-3β and β-Catenin/TCF Pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1038_npp_2008_198

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1038_npp_2008_198

Other Identifiers

ISSN

0893-133X

E-ISSN

1740-634X

DOI

10.1038/npp.2008.198

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