Reversal of Autoimmune Toxicity and Loss of Tumor Response by Interleukin-17 Blockade
Reversal of Autoimmune Toxicity and Loss of Tumor Response by Interleukin-17 Blockade
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Publisher
United States: Massachusetts Medical Society
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Language
English
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Publisher
United States: Massachusetts Medical Society
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Scope and Contents
Contents
In a patient with colon cancer and a history of autoimmunity, skin and gastrointestinal toxicity developed after the receipt of pembrolizumab. Interleukin-17 blockade reversed the autoimmunity but led to tumor progression.
To the Editor:
Patients with autoimmune diseases have typically been excluded from immunotherapy clinical trials, althoug...
Alternative Titles
Full title
Reversal of Autoimmune Toxicity and Loss of Tumor Response by Interleukin-17 Blockade
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Record Identifier
TN_cdi_crossref_primary_10_1056_NEJMc1703047
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1056_NEJMc1703047
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMc1703047