Speeding up drug discovery with high-quality and high-reliability crystallography-based library scre...
Speeding up drug discovery with high-quality and high-reliability crystallography-based library screening
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Language
English
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Contents
Fragment-based drug discovery (FBDD) can more efficiently scan chemical space to provide novel hits for developing new therapeutics. Protein X-ray crystallography (PX) is the gold standard for experimentally defining exact binding of a ligand to asses direct target engagement. Absence of crystal structures of target-ligand complexes is a significan...
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Full title
Speeding up drug discovery with high-quality and high-reliability crystallography-based library screening
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TN_cdi_crossref_primary_10_1063_4_0000310
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1063_4_0000310
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ISSN
2329-7778
E-ISSN
2329-7778
DOI
10.1063/4.0000310
