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A Functional Genetic Screen Identifies Regions at the C-Terminal Tail and Death-Domain of Death-Asso...

A Functional Genetic Screen Identifies Regions at the C-Terminal Tail and Death-Domain of Death-Asso...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_020519497

A Functional Genetic Screen Identifies Regions at the C-Terminal Tail and Death-Domain of Death-Associated Protein Kinase That Are Critical for Its Proapoptotic Activity

About this item

Full title

A Functional Genetic Screen Identifies Regions at the C-Terminal Tail and Death-Domain of Death-Associated Protein Kinase That Are Critical for Its Proapoptotic Activity

Publisher

United States: National Academy of Sciences of the United States of America

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2000-02, Vol.97 (4), p.1572-1577

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences of the United States of America

More information

Scope and Contents

Contents

Death-associated protein kinase (DAP-kinase) is a Ca+2-calmodulin-regulated serine/threonine kinase with a multidomain structure that participates in apoptosis induced by a variety of signals. To identify regions in this protein that are critical for its proapoptotic activity, we performed a genetic screen on the basis of functional selection of sh...

Alternative Titles

Full title

A Functional Genetic Screen Identifies Regions at the C-Terminal Tail and Death-Domain of Death-Associated Protein Kinase That Are Critical for Its Proapoptotic Activity

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1073_pnas_020519497

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_020519497

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.020519497

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