A Feedback Mechanism Regulates Monoallelic Odorant Receptor Expression
A Feedback Mechanism Regulates Monoallelic Odorant Receptor Expression
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
In olfactory neurons, expression of a single odorant receptor (OR) from a repertoire of > 1,000 genes is required for odor coding and axonal targeting. Here, we demonstrate a role for OR protein as an essential regulator in the establishment of monoallelic OR expression. An OR-promoter-driven reporter expresses in a receptor-like pattern but, unlik...
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Full title
A Feedback Mechanism Regulates Monoallelic Odorant Receptor Expression
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TN_cdi_crossref_primary_10_1073_pnas_0307986100
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_0307986100
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0307986100
