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Androgen receptor is a tumor suppressor and proliferator in prostate cancer

Androgen receptor is a tumor suppressor and proliferator in prostate cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_0804700105

Androgen receptor is a tumor suppressor and proliferator in prostate cancer

About this item

Full title

Androgen receptor is a tumor suppressor and proliferator in prostate cancer

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2008-08, Vol.105 (34), p.12182-12187

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Targeting androgens/androgen receptor (AR) functions via androgen deprivation therapy (ADT) remains the standard treatment for prostate cancer. However, most tumors eventually recur despite ADT. Here we demonstrate that the prostate AR may function as both a suppressor and a proliferator to suppress or promote prostate cancer metastasis. Results fr...

Alternative Titles

Full title

Androgen receptor is a tumor suppressor and proliferator in prostate cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1073_pnas_0804700105

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_0804700105

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0804700105

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