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amyloid β-peptide is imported into mitochondria via the TOM import machinery and localized to mitoch...

amyloid β-peptide is imported into mitochondria via the TOM import machinery and localized to mitoch...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_0806192105

amyloid β-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae

About this item

Full title

amyloid β-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2008-09, Vol.105 (35), p.13145-13150

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

The amyloid β-peptide (Aβ) has been suggested to exert its toxicity intracellularly. Mitochondrial functions can be negatively affected by Aβ and accumulation of Aβ has been detected in mitochondria. Because Aβ is not likely to be produced locally in mitochondria, we decided to investigate the mechanisms for mitochondrial Aβ uptake. Our results fro...

Alternative Titles

Full title

amyloid β-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1073_pnas_0806192105

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_0806192105

Other Identifiers

ISSN

0027-8424,1091-6490

E-ISSN

1091-6490

DOI

10.1073/pnas.0806192105