Hippo-Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesi...
Hippo-Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Loss of Hippo signaling in Drosophila leads to tissue overgrowth as a result of increased cell proliferation and decreased cell death. YAP (a homolog of Drosophila Yorkie and target of the Hippo pathway) was recently implicated in control of organ size, epithelial tissue development, and tumorigenesis in mammals. However, the role of the mammalian...
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Full title
Hippo-Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis
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Record Identifier
TN_cdi_crossref_primary_10_1073_pnas_0912203107
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_0912203107
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0912203107
