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Structure and mechanism of proton transport through the transmembrane tetrameric M2 protein bundle o...

Structure and mechanism of proton transport through the transmembrane tetrameric M2 protein bundle o...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1007071107

Structure and mechanism of proton transport through the transmembrane tetrameric M2 protein bundle of the influenza A virus

About this item

Full title

Structure and mechanism of proton transport through the transmembrane tetrameric M2 protein bundle of the influenza A virus

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2010-08, Vol.107 (34), p.15075-15080

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

The M2 proton channel from influenza A virus is an essential protein that mediates transport of protons across the viral envelope. This protein has a single transmembrane helix, which tetramerizes into the active channel. At the heart of the conduction mechanism is the exchange of protons between the His37 imidazole moieties of M2 and waters confin...

Alternative Titles

Full title

Structure and mechanism of proton transport through the transmembrane tetrameric M2 protein bundle of the influenza A virus

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1073_pnas_1007071107

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1007071107

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1007071107

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