Molecular basis for amyloid-β polymorphism
Molecular basis for amyloid-β polymorphism
About this item
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Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publication information
Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Amyloid-beta (Aβ) aggregates are the main constituent of senile plaques, the histological hallmark of Alzheimer’s disease. Aβ molecules form β-sheet containing structures that assemble into a variety of polymorphic oligomers, protofibers, and fibers that exhibit a range of lifetimes and cellular toxicities. This polymorphic nature of Aβ has frustra...
Alternative Titles
Full title
Molecular basis for amyloid-β polymorphism
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_crossref_primary_10_1073_pnas_1112600108
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1112600108
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1112600108
