Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies
Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies
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Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Broadly neutralizing HIV antibodies (bNAbs) can recognize carbohydrate-dependent epitopes on gp120. In contrast to previously characterized glycan-dependent bNAbs that recognize high-mannose N -glycans, PGT121 binds complex-type N -glycans in glycan microarrays. We isolated the B-cell clone encoding PGT121, which segregates into PGT121-like and 10-...
Alternative Titles
Full title
Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies
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Record Identifier
TN_cdi_crossref_primary_10_1073_pnas_1217207109
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1217207109
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1217207109
